Auditor
5.1K posts

Auditor
@auditor112017
Retired Internal Auditor (CISA), Accountant, and Info Sec Engineer. Followed biotech, pharma, banking and tech sectors for more than 25 years.
Katılım Ekim 2017
46 Takip Edilen264 Takipçiler

$SGMO Fabry trial just updated
2 year data should now be available with data cutoff april 10, 2026 (last friday)
tic toc ... PR
#version-content-panel" target="_blank" rel="nofollow noopener">clinicaltrials.gov/study/NCT04046…
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@BiotechAnalysst Are potential business partners for Fabry waiting for this dataset? $sgmo
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@JimFergusonUK The 1.4 billion people claim by the CCP seems not realistic due to the one child policy enforced for several decades. Some experts are saying it is more like 600 million!
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🚨 CHINA RESPONDS — “A WALL OF STEEL”
President Xi Jinping issues a clear warning:
China will not be intimidated.
China will not be pressured.
China will not back down.
“Anyone who attempts to bully us
will collide with a wall of steel
forged by 1.4 billion people.”
This isn’t diplomatic language—
It’s a message.
Strength.
Resolve.
Defiance.
As tensions rise in the Gulf—
The world’s second superpower
is now speaking directly.
Because when China steps in—
The stakes don’t just rise.
They change completely.
Watch this closely.
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@Orlando71156528 If Russia interferes, U.S. will send long range missiles and other advance weaponry to Ukraine! Likewise with China! Trump will do more with Taiwan and the Asian allies!
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@Franca_ole $sgmo Grok simplifies this tech doc on Nav 1.7 and 1.8
x.com/i/grok/share/8…
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$VRTX $SGMO
The paper shows that the excitability of pain neurons is not determined by individual sodium channels, but rather by their interaction. Different combinations of these channels give rise to different types of neurons, each with its own response to stimuli. In some cases, strong synergistic effects occur, such that the effects of individual channels can reinforce or modify one another. These findings explain why therapies that target only a single channel are often ineffective. Instead, the results suggest that future treatment approaches must take multiple channel types into account simultaneously in order to influence pain more effectively.
biorxiv.org/content/10.648…
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@realgerhardtvdm Wishful thinking; not after what they have done to Hong Kong!
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🚨🇨🇳 MASSIVE BREAKING NEWS, WESTERN MAINSTREAM MEDIA KEEPS HUSH HUSH:
President Xi Jingping meets with Cheng Li-wun Chairwoman of Taiwan's next ruling party (KMT), in Beijing.
It's happening, reunification between Taiwan province and China mainland, The U.S. and Japan are crying like we've never seen before!
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@ArtsStocks @investuniversal Salanersen for SMA uses $ions new NMA tech for splicing. Don't think Elsunersen uses splicing. $prax
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@auditor112017 @investuniversal Don’t need siRNA, $ions currently dosing every six months and every year in SMA trial. $prax #neurology
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@ArtsStocks @investuniversal Believe monthly dosing for elsunersen.
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Perhaps, it is time for $tak to return the Huntington program back to $sgmo. Why is Takeda still holding onto $sgmo asset while they have been terminating CNS related agreements left and right.
biopharmadive.com/news/fda-exped…
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@investuniversal Look for EMBRAVE3 data read out for elsunersen in 2026.
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@investuniversal Looks like $ions is going to get another potential large revenue stream similar to $biib spinraza royalties for SMA. $Ions gets tiered royalties in the low-20s percent range on worldwide net sales of elsunersen! $prax
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@investuniversal Not sure if any of the analysts have priced this into $ions sp projection.
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@FormalyTwilter $ions $rhhby The partnership with Roche on Alzheimer could be this APOE4 target. Likely, will be using $ions more advance CNS tech.
x.com/i/grok/share/1…
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$BIIB $IONS
#Alzheimersgene 研究者たちが Nell2 の産生を減少させたところ、 #APOE4遺伝子 を持つ成体マウスにおいても、ニューロンが正常なサイズと発火パターンに回復した。
これは、#Alzheimers を阻害する薬の開発の可能性を示唆している。 ⬇️
Art🇺🇸🇮🇱🇺🇦@ArtsStocks
#Alzheimersgene When the researchers reduced the production of Nell2 neurons recovered their normal size and firing patterns even in adult mice with the #APOE4 gene. This points toward the possibility of developing drugs that block #alzheimers $biib $ions medicalxpress.com/news/2026-04-a…
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William Blair #Gene #Editing report highlighting $SGMO
modular integrase (#MINT) platform
$SGMO preprint:
biorxiv.org/content/10.110…


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