Ayan

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Ayan

@ayanobacter

PhD in Synbio, Entrepreneur, Open Science, Researching and Writing About Futures and Frontiers

Katılım Şubat 2022
283 Takip Edilen677 Takipçiler
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Ayan
Ayan@ayanobacter·
I have a new piece on DNA synthesis ceilings, an exciting new assembly architecture (Sidewinder), and the emerging digital-physical biology stack that is finally converging in a way that promises to make rapid biological iteration a reality curiosity is the next frontier of building with biology (link below 🧬)
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Cyrus
Cyrus@cyrusclarke·
After two years in the US I'm sorry to say i've finally fallen in love with A/C. Also I'm running a Physical AI event next week at Media Lab next week for #BosTechWeek with demos from all the viral AI projects you've seen on your feed. Get on the list before it gets full: partiful.com/e/4wahZxSOBB3I…
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Ayan
Ayan@ayanobacter·
Thanks for reading and sharing! I think finding this balance between adapting to existing measurement frameworks/tools vs. the more messy, less tangible dimensions of life itself will actually be a big test for modern bio. I hope you’ll also enjoy the next piece, which will explore some of the less obvious edges of this question.
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Yang Fan 范阳
Yang Fan 范阳@Yang_Supertramp·
Do you believe in scientific intuition — and if so, how would you define it? A great read today: “Scientific Intuition in the Agentic Age On taste, tacit knowledge, and the critical parts of scientific cognition that you can't just scale past. ” By Ayan Abukar.
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Fyodor Urnov@UrnovFyodor

I prompted the “deep literature” mode of Edison Scientific to write a comprehensive review on the biology of a gene that I know well. Twenty five min later it sent a 17 page PDF. It was, as best as I can tell, flawless. Folks, we are not in Kansas anymore. Don’t at me - try it.

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Ayan@ayanobacter·
@mkoeris Glad this reached you, would love to know your thoughts on this especially from your position. I wrote it thinking a lot about the post Sputnik mobilization in the US around education reform where it was being treated as a national security problem- intuition being a core pillar.
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Ayan
Ayan@ayanobacter·
Post Sputnik, the US responded by treating education as a national security problem. In 1959 they gathered the leading scientific minds, backed by major national bodies, and held a conference in Woods Hole, MA to identify where science education was going wrong and how to reform it at scale. 4 core themes emerged, one being: “the nature of intuition” They understood the significance of intuition. (though they ultimately struggled to define and operationalize it) Today we spend enormous resources advancing tools and more easily measurable methods. Yet we see comparatively negligible investment in trying to understand scientific intuition itself and the important role it appears to play in Nobel worthy breakthrough ideas/generally extraordinary scientific outcomes.
Ayan@ayanobacter

In my new piece I'm confronting the critical parts of scientific cognition that you can't just scale past. I’ve been thinking a lot about which human intelligences we’re actually aiming to replicate and optimize artificially, and which ones we seemingly reveal in the process.

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Ayan
Ayan@ayanobacter·
in light of recent outbreaks, I must ask who's working on xenonite PPE
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Ayan@ayanobacter·
@dwddao This is v true, lots of academic research is still trapped in the reputation and reward systems of trad publishing
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Ayan
Ayan@ayanobacter·
I'm seeing a lot of criticism of these guys, which on one side I get, but on the other, the whole point of being young is that you do wake up and think you can build a company that's first goal is to cure all cancers there's something really cool about that, even if bio folks are initially left with lots of technical question marks
Y Combinator@ycombinator

FinalDose is building the first programmable drug platform - a single smart drug molecule that finds diseased cells by their DNA and destroys them. They're starting with all cancers. Congrats on the launch, @Jeffliu6068Liu, @sklin_lite, and @liyaohuang2! ycombinator.com/launches/QKj-f…

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Ayan
Ayan@ayanobacter·
My new piece is partly inspired by this discussion series I read about that took place from 1970 to 1986, where the Swedish Broadcasting Corporation hosted a recurring roundtable called “Science and Man” where they brought together Nobel laureates in physics, chemistry, and medicine shortly after each year’s ceremony and asked them if they believed in scientific intuition. Of the 84 laureates surveyed, 72 said yes. Even those that said no/abstained, described something very similar. Intuition appeared to be real and seemed to matter to them on some level, even if almost none of them could fully explain it. This question feels deeply urgent today in the age of the AI scientist and automation. We really need to interrogate what a leap in discovery actually is. Whether it’s a process, an event, or both. Whether it lives in the method or somewhere between the method and the individual (madness) embodying it. Whether the thing we’re trying to automate is the output of scientific thinking, or something irreducibly prior to it.
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Ayan@ayanobacter

In my new piece I'm confronting the critical parts of scientific cognition that you can't just scale past. I’ve been thinking a lot about which human intelligences we’re actually aiming to replicate and optimize artificially, and which ones we seemingly reveal in the process.

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Ayan
Ayan@ayanobacter·
In my new piece I'm confronting the critical parts of scientific cognition that you can't just scale past. I’ve been thinking a lot about which human intelligences we’re actually aiming to replicate and optimize artificially, and which ones we seemingly reveal in the process.
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Nora Kased
Nora Kased@lunarcycling·
@ayanobacter Okay, and I thought I made nerdy chemistry jokes 😂💕
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