Bin Wu Lab

We applied the method to study ZNF598, an E3 ligase that detects collided ribosomes. We found that ZNF598 can detect ribosomes beyond the leading one in the queue. It is a limiting factor in ribosome associated quality control.

Very proud that the thesis work of Ana De La Cruz from ⁦@BiophysicsJHMed⁩ ⁦@JHU_Mol_Biophys⁩ is published on ⁦@embojournal⁩. Great collaboration with ⁦@GreenLabJHMI⁩. We visualize mRNA, translation and a regulatory protein in cells. embopress.org/doi/full/10.10…

My lab at Brown University is hiring a postdoctoral fellow! We develop single-molecule imaging technologies to dissect the spatial regulation of gene expression. For more information about my lab, visit weihan-li.com Please help spread the word! #RNA #imaging

The latest designs of a new Life Sciences Building on the Johns Hopkins East Baltimore medical campus were recently shared with city planners. bit.ly/3XVkHA4 Groundbreaking on the Life Sciences Building is anticipated for the summer of 2025.

@TheBlanchardLab Wow, congrats, Scott, well deserved!

I am deeply honored to receive the 2025 Kazuhiko Kinosita Award in Single-Molecule Biophysics from the Biophysical Society. Our achievements build on the foundations laid by many great scientists, including all past recipients of this award. I would like to extend my sincere gratitude to the Biophysical Society and the award committee for recognizing our team’s contributions. I also thank my scientific mentors, the colleagues with whom I’ve had the opportunity to collaborate, and the many talented young scientists whose dedication brought our research to fruition. Special thanks must also go to the leadership at St. Jude Children’s Research Hospital for their vision to create a center for single-molecule imaging, enabling us and others at our institution to dig deeper into the roles of structural dynamics in complex biological systems to disease. The future of single-molecule biophysics is brighter than ever, and I hope our contributions will inspire the next generation of scientists.

Meet Jeremy Nathans, the 2024 World Laureates Association Prize (#WLAPrize) laureate in Life Science or Medicine. As a professor of molecular biology and genetics, neuroscience, and ophthalmology at the @JohnsHopkins School of Medicine, he has made groundbreaking contributions to the discovery of genes, regulation and plasticity underlying human color vision. Know more about the scientist: bit.ly/4d8WVWS #WLAPrize2024

We are hiring! Position open for a new assistant professor in the Department of Biophysics & Biophysical Chemistry in @HopkinsMedicine . Considering all areas in experimental and computational biophysics. Please spread the word. apply.interfolio.com/154014

Our department @JohnsHopkinsMBG (mbg.jhmi.edu) is hiring! Join us to start your independent lab in a collegial and stimulating environment! apply.interfolio.com/149819 Applications will be reviewed on a rolling basis starting September 15, 2024 so don't wait to apply : )

Congratulations, Dr. Ana De La Cruz! ⁦@anadlc13⁩

@YiliangDing Congrats, Yiliang!

promoted to Professor😀Many thanks to the current and previous lab members🙏I am super grateful for having great collaborators through the years🙏And many thanks to all the friends who have been supporting me and my lab in the past 10 years! Thank you all🙏❤️❤️❤️

Bloomberg Philanthropies gives $1B to Johns Hopkins University. This gift makes the School of Medicine tuition-free for students from families earning under $300,000, and students from families earning up to $175,000 will receive a full ride, including living expenses.

@angalus_d @taekjip @yliu_UofU @BiophysicsJHMed @BCMB_JHMI Thanks, Sulagna

@binwu1 @taekjip @yliu_UofU @BiophysicsJHMed @BCMB_JHMI Congratulations Bin! Great work!

Excited to share that our paper on transcription repression after DNA double-strand break is online. Great collaboration with ⁦@taekjip⁩ and ⁦@yliu_UofU⁩, spearheaded by Shuaixin He ⁦@BiophysicsJHMed⁩ ⁦@BCMB_JHMI⁩ cell.com/cell-reports/f…

DNA break induces rapid transcription repression mediated by proteasome-dependent RNAPII removal dlvr.it/T94GC5

We used very-fast CRISP to induce single DSB and observed transcription repression in minutes. The repression propagates along chromosome for hundreds of kb. Interestingly, the rapid repression doesn't depend on H2AK119 ubiquitination, but relies on proteasome to remove RNAPolII.

@Evident_LS @CWolberger @LCochella @jiexiao_lab @jmcoller @InoueLabJHMI Special thanks to the lab manager Darcey McDowell and the camp aids Kodi Harris, Fujr Osman and Hannah Wu.

The students learned microscopes, DNA, crystal, worms, visual illusion, coral, cells, slimes. Thank you, @Evident_LS, Jeremy Nathans, @CWolberger, Bethany Gray, @LCochella , Josh Modell, Bear Huang, @jiexiao_lab , Caren Meyers, @jmcoller, @InoueLabJHMI and your amazing labs.

We had a great week of Fun with Science Summer Camp. 16 5th and 6th graders from Baltimore area attended this annual event supported by @BiophysicsJHMed and Career for Science and Medicine. 11 Hopkins lab and @Evident_LS organized fun and engaging activities.

Baltimore middle schoolers learning about crystal lattices in Fun With Science Camp, an annual program run by @binwu1 in @BiophysicsJHMed .

@cryoET @wd_hale @NatureSMB Congrats, Ed and the team!