Liquid Biopsy

@Flomicsbiotech #LiquidBiopsy #ctDNA #CancerResearch #Oncology #PrecisionMedicine #CancerEarlyDetection #BloodTest For more: lnkd.in/e5mfqkQW

@Flomicsbiotech Critically, it detected Stage I cancers with 80% sensitivity, meaning it catches cancer when treatment is most effective.

A blood test just detected 5 cancers at once in 1,000 patients. Here's what 92% AUC actually means.

9/ 💬 Will molecular endpoints become the new gold standard for early oncology trials? Curious to hear from: clinicians • trial designers • biotech • regulators #ctDNA #Oncology #ClinicalTrials #PrecisionMedicine #DrugDevelopment #Biotech

8/ ⚡ If ctDNA predicts outcomes earlier and more precisely… Do RECIST-based endpoints still make sense as the primary readout in Phase I/II? 👇

🧬 Clinical trials are being rewritten, in real time. Oncology trials aren’t waiting months for radiographic endpoints anymore. They’re watching tumour DNA disappear from blood. 👇

💬 Curious to hear how others are thinking about multi-omics + AI in liquid biopsy. #liquidbiopsy #multiomics #oncology #AI Pic: ChatGPT

🤖 The future isn’t choosing one biomarker. It’s teaching AI to translate and integrate all of them into a single clinical narrative. When the signals disagree, which one do you trust? Or do you trust the system that understands all of them?

🧬 Liquid biopsy is NOT a test. It’s a platform. Yet we still talk about it like one signal tells the whole story. ctDNA cfRNA Exosomes Proteins Methylation Each speaks a different biological language. Each captures a different moment in disease.

• Potentially change outcomes, not just timelines If ctDNA tells us relapse is coming… should we wait until scans confirm Pic: Gemini 📕*Circulating tumor DNA for MRD detection in colorectal cancer: recent advances and clinical implications

🚨 What if cancer relapse is already detectable… months before scans show anything? ctDNA doesn’t wait for tumors to be “visible.” 📊 Multiple studies show that serial ctDNA can flag recurrence a median of ~8–9 months earlier than imaging: *

👉 in some cases >16 months before radiology 👉 across CRC and other solid tumors That’s half a year (or more) of lost opportunity if we rely on scans alone. 🧬 Earlier signal = earlier intervention • Adjust treatment sooner • Monitor minimal residual disease