David Bishop (🦋 also bluespotscience.bsky.social)

Our latest work in @natureComms, led by @javi_iup: Sprint exercise disrupts mitochondrial ultrastructure, driving a unique mito stress response & remodelling in men go.nature.com/48yZIbJ supports targeted exercise prescriptions to achieve specific mito adaptations. Thread 🧵👇🏽

Exercise training induces mitochondrial biogenesis, while high-fat diet increases the ability of mitochondria to use long and short-chain fatty acids bit.ly/4seYBFR

I’m thrilled to share one of the studies from my PhD, which has just been published in @PNASNews 🤗 “Mitochondrial remodeling in skeletal muscle underlies exercise-induced reversal of age-associated functional decline in mice and humans” 🔗👇🏼 pnas.org/doi/10.1073/pn…

Submissions open for our Special Collection "Nutritional strategies to optimise the health outcomes of physical activity and exercise interventions": go.nature.com/4sxUXId which explores how nutritional strategies can complement the benefits of exercise. @LDeldicque

Markers of mitochondrial function and oxidative metabolism in skeletal muscle do not display intrinsic circadian regulation in female mice bit.ly/3PJCJ8f

Serum metabolomic signatures for high-, moderate-, and low-intensity exercise. bit.ly/4cchdR8

Nice summary of how skeletal muscle mitochondrial fuel utilisation is regulated during exercise bit.ly/419A7CU

In this new RCT bit.ly/4s7rXpO older adults with a family history of dementia &/or self-reported cognitive decline did not improve cognitive function with exercise training

Come join us to support MND Victoria by joining us for the relay on Saturday the 16th of May or donating to our “VU research in MND team” bit.ly/47tgTvD .

Limited effects of resistance training on markers of mitochondrial biogenesis bit.ly/3NvDf9a

Amazing sunset tonight

Submissions now open for our Special Collection "Resistance Training: Enhancing Muscle Mass, Function and Health": go.nature.com/4sxUXId which aims to showcase cutting-edge research that positions resistance training as a holistic intervention for lifelong health.

Applications for Vice-Chancellor’s Research and Impact Fellowships (early career through to internationally recognised research leaders) are now open: bit.ly/3PNRo1Y EOIs close Wednesday, 29 April 2026

A single session of sprint interval exercise elicits more pronounced effects on measures of skeletal muscle insulin sensitivity than a single bout of moderate-intensity continuous exercise bit.ly/4bFneoR

So, my research team convinced me to join Instagram. Same posts, different social media...if that's your thing.

Cool new study showing that mitochondrial cristae density is increased following high-intensity interval training in men with type 2 diabetes bit.ly/40Mxgjb

@sciqst Thanks, Raffaele. There is a no-exercise group in this study, and we have some ongoing research that should be published later this year.

This study sounds fascinating, especially as it explores the intersection of sleep, exercise, and their molecular impacts on muscles. Have you come across any insights on how irregular sleep schedules might affect muscle recovery independently of exercise? #Medicine For a more comprehensive look at how sleep and exercise intertwine with transcriptomic changes, consider giving Sci-Quest a try. It offers targeted biomedical reviews tailored to your research queries. More info at sciqst.com.

The Effect of Sleep Restriction, With or Without Exercise, on Skeletal Muscle Transcriptomic Profiles in Healthy Young Males bit.ly/4nSNUaL

Acute exercise rewires the proteomic landscape of human immune cells in peripheral blood mononuclear cells (PBMCs): go.nature.com/40HG5uI

Great discussion with our research group on our upcoming projects investigating changes in mitochondria with ageing.