sganguly

Privileged to be part of a team that encourages learning through such high-quality academic interactions. Deeply grateful for the knowledge and insights shared by our esteemed guest, Prof. Siddhartha Ganguly. @bmtdoc63 @DrPMPGI @ArihantDr @Charanpreet_14 @Aditya_PGI @alka_khadwal

MGUS and asymptomatic Creatine Kinase elevation. After ruling out statin use or hypothyroidism, is there any association between plasma cell disorders and CK? Macro CK type I is CK associated with immunoglobulins. Very rare Nemaline Myopathy. Finally AL Amyloid of muscles.

A post caught my eye so commenting here. Antibiotics derived from Streptomyces are called “Mycins” with a Y. Like Streptomycin. Antibiotics from micromonospora end with “micin” with an i like in Gentamicin. So there is no Y in Gentamicin.

@MoarSahitoPTI Why Gentamicin is spelled with an i in “micin” rather than y as in “mycin”?

Why is Gentamicin commonly used in dialysis patients despite its nephrotoxicity? 💉🤔

@allisonoconn Hyperhomocysteinemia

Today I learned that while clots in veins can be caused by all sorts of things, clots in arteries are usually caused by cancer or anti-phospholipid syndrome (APLS).

After tonight, who else is going to use Vyxeos? #ASH25 #Paradigm

@nihardesai89 @PanktiMehta24 You should have been in Sunny Orlando instead

Toronto this morning ❤️

Such a pleasure to meet team PGI at #ASH25. After Calcutta Medical College, PGIMER was my second Alma Mater. Honor to meet ⁦@DrPMPGI⁩ ⁦@Aditya_PGI⁩. Looking forward to the visit in January.

@allisonoconn An internist= Human Systems Analyst

I think I’ll go to LinkedIn and start referring to myself as a cancer “disruptor”

At the entrance of the #Epcotcenter @WaltDisneyWorld there is a wall of legacy where one can leave a message for posterity. We did that when our kids were really young. Those were the days. In between meetings went there to see if I could locate that message after 23 years. 👇🏽👇🏽

@aditya_gan3500 Long time ago I learnt that the orbitalis muscles guarding superior and inferior orbital fissures are innervated by sympathetics and act as valves for retro orbital venous plexus drainage. In flaccid paralysis of orbitalis muscles retro orbital venous plexus collapses. 🤷🏽‍♂️I am old

@bmtdoc63 Apparent enophthalmos sir Two theories 1. Real loss of IOP d/t loss of sympathetic supply 2. Apparent enophthalmos d/t ptosis of upper eye lid and reverse ptosis of lower one

That is why I am a medical historian. Amateur of course. As Sidhu Jyatha of Feluda fame said You cannot learn a subject without knowing its history. That history was created by people. You must know their story. Thank you all. #MedTwitter #NeuroTwitter #NephTwitter

Look for the lady with the paddle #Baggageclaim #Orlandointernationalairport #ASH2025

Not uncommonly SPEP is checked for neuropathy and a diagnosis is made with MGUS. Is it related? If it’s Axonal then check for cryoglobulin. If demyelinating then usually IgM or with Anti MAG. POEMS is clinical and usually Lambda. Don’t forget Amyloid. Axonal IGG Kappa Not related

@allisonoconn It’s a good idea to make a smart phrase documenting chemo discussions and informed consent and then tweak based on individual chemotherapy. How did you document the consent in this case?

I prescribed my first chemotherapy today!!!! ✨💫💉💕

Looking forward to serve as the steering committee member of the Cellular Therapy Initiative ⁦@AACI_Cancer⁩. Strive to decentralize cellular therapy. Make it available to all so patients can receive this promising treatment closer to home. aaci-cancer.org/news-aaci-cell…

A patient with HIV with #PJP pneumonia on inhalation Pentamidine presents with spontaneous pneumothorax and Xray shows upper lobar #pneumatocoeles and #lateralpneumonia. What happened? Due to aerodynamics, upper lobar distribution of Pentamidine is inadequate causing above change

@Sage_medics Find the dimple in a prone position. Go a little superior and lateral from the dimple and voila! The best place for bone marrow aspirate and biopsy on the superior iliac crest.

Guess the name? Do you have it?🌝

@DrAkhilX Pentamidine for PJP is OK after transplant/CAR T. Switch to Bactrim when counts OK. Atovaquone is OK except taste. Dapsone is good but monitor for Methemoglobinemia. Long term inhalation especially in HIV patients can cause lateral pneumonia. Can cause upper lobe pneumatocoeles.

What are the indications?

@RenoHemonc The purpose of my message was that to document CR/MRD, one would need a bone marrow biopsy. With Blood tests and urine, even if all negative one can tell only VGPR and not beyond. With immunotherapy, persistent MRD neg status at less than 10 to the power 6 is very comforting.

@bmtdoc63 Or give fixed duration Tec Dara frontline for 100% CR / MRD negative 🙂

In Myeloma, if the M protein at diagnosis was 4g/dl; Very Good Partial Remission or VGPR is defined by >90% reduction. Hence, just move the decimal to one place left. In this case M protein <0.4 g/dl would be VGPR. Even if SPEP/IFE negative, to document CR, we need Bone Marrow.