Etienne

🎉Our latest paper "Stereorandomized Oncocins with Preserved Ribosome Binding andAntibacterial Activity" is now published on @ACSBioMed! Read it here👉pubs.acs.org/doi/10.1021/ac… @DCBPunibern @unibern @reymondgroup #oncocin #antibacterial #AMP

An efficient submonomer synthesis of inverse-polyamidoamide (i-PAMAM) dendrimers is reported and used to investigate antibacterial i-PAMAMs. @reymondgroup @jrjrjlr @HippolytePrsn @Xiao67644111515 @bonvin15 @atomicsqu1rrel @DCBPunibern onlinelibrary.wiley.com/doi/10.1002/hl…

🎉Check out our latest paper "Submonomer Synthesis of Inverse Polyamidoamine (i-PAMAM) Dendrimer Antibacterials" by @HippolytePrsn , Xiaoling Hu, @bonvin15 , Jérémie Reusser and @jrjrjlr in Helvetica Chimica Acta! 👉Read the full version: onlinelibrary.wiley.com/doi/10.1002/hl… #antibacterial

🎉Thrilled to announce our new publication in @ACSBioMed pubs.acs.org/doi/10.1021/ac… 🧪Peptide-to-peptoid mutations lower toxicity and degradation of an antimicrobial peptide and change its killing mechanism. 🦠@bonvin15 @jrjrjlr @DCBPunibern #chemtwitter #peptoid #AMR #antibiotics

📢Check our latest paper "Multistep retrosynthesis combining a disconnection aware triple transformer loop with a route penalty score guided tree search" @ChemicalScience @DavidKreutter @jrjrjlr 👉pubs.rsc.org/en/content/art… @DCBPunibern #TransformerModel #ML #AI #chemtwitter

📢Check our latest paper @ACSBioMed about Diastereomeric Optimization of an α-Helical Antimicrobial Peptide! @HippolytePrsn Read the corresponding article here: 👉pubs.acs.org/doi/10.1021/ac… @DCBPunibern #chemtwitter

📢Check out our latest paper @HelvChimActa by @bonvin15 doi.org/10.1002/hlca.2… We redesigned polyamidoamine dendrimers by moving the carbonyl across the amide nitrogen to form HPLC pure inverse PAMAMs, stable and showing potent antibacterial effects @DCBPunibern #chemtwitter

📢The #SCS Fall Meeting 2022 takes place on Sep 8 at University Zurich! Don't miss out on the short talks and poster presentations from our group @AlineCarrel @bonvin15 @HippolytePrsn @Ye_Buehler More details👉fm22.scg.ch @SwissChemistry @DCBPunibern #chemtwitter

Towards handedness of a mixed chirality bicyclic antimicrobial peptide and how variation of chirality can abolish hemolytic and preserve antimicrobial activities. Here's the preprint: chemrxiv.org/articles/prepr… @reymondgroup @DCBunibern #crystallography #antimicrobial #peptide