

Ricardo Castillejos
635 posts

@castialon
Urología Oncológica y Andrología, INCMNSZ Profesor Titular de Urologia, UNAM, Presidente@smumexico
















12 patients with metastatic cancer. Melanoma, breast, kidney. Doctors injected a re-engineered antibody (CD40 agonist) into a single tumor. Not IV. Not systemic. One local shot. The result: tumors shrank across the entire body, including at sites that were never touched. 2 of 12 patients hit complete remission. The injected tumors didn’t just shrink. They were replaced by organized immune tissue, tertiary lymphoid structures, essentially training camps for cancer-killing T cells. Zero severe side effects. The concept: instead of flooding the body with immunotherapy and hoping it finds the cancer, turn one tumor into a vaccine against itself. Train the immune system locally. Let it hunt globally. Nearly 200 patients now in expanded trials across bladder, prostate, and brain cancers. Published in @Cancer_Cell by Jeffrey Ravetch’s lab at @RockefellerUniv and @MSKCancerCenter




Discover the program of the 3rd SMU Symposium “The Urology ring: where evidences goes head-to-head” 🥊 12 Experts fighting 🛎️ 6 Debates and referees You will be part of the decisión, vote! 🗓️ May 16, 2026. 🕗 8:00 - 10:00 a.m. 📍 Room 143B 💻 Check out the program: auanet.org/AUA2026 #AUA26 @raevti @Dr_KevinZorn @spsutkaMD @moeltemamy @DrJohnDenstedt @GuidoGiusti @uretericbud @SimoneCrivella2 @JanetKukreja @BenjaminPradere @UroRecon - - - Descubre el programa del 3er. Simposio de SMU en “El ring de la Urología: donde la evidencia se enfrenta cara a cara” 🥊 12 expertos en acción 🛎️ 6 debates y árbitros ¡Tú puedes ser parte de la decisión con tu voto! 🗓️ 16 de mayo de 2026. 🕗 8:00 - 10:00 hrs. 📍 Sala 143B 💻 Consulta el programa: auanet.org/AUA2026 #SMU26 #JuntosTrascendemos #Urología #Urology














