Charalampos Tzoulis

142 posts

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Charalampos Tzoulis

Charalampos Tzoulis

@chtzoulis

Professor of Neurology and Neurogenetics; Director, Neuro-SysMed Center; Head, Neuromics Group; Director, K.G Jebsen Center for Parkinson's disease

Norway Katılım Haziran 2009
231 Takip Edilen296 Takipçiler
Charalampos Tzoulis retweetledi
The Science of Parkinson's
The Science of Parkinson's@ScienceofPD·
Really excited to have @chtzoulis at the @CureParkinsonsT Autumn 2025 Research Update meeting today talking about his new Sleipnir clinical trial platform (although he is talking a lot about Star Wars & how it relates to #Parkinsons at the moment)
The Science of Parkinson's tweet media
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Charalampos Tzoulis
Charalampos Tzoulis@chtzoulis·
Our latest work provides insights into the cell-specific gene expression landscape of Parkinson's disease (PD), PD caused by LRRK2 mutations, and MSA. We also explore cell type-specific transcriptomic signatures associated with α-synuclein pathology: academic.oup.com/brain/article/…
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Charalampos Tzoulis
Charalampos Tzoulis@chtzoulis·
Fresh from our lab - Analyses of muscle biopsies from persons with Parkinson's disease indicate the existence of a subgroup with impaired mitochodrial function. Another step towards biological stratification of PD: nature.com/articles/s4385…
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Charalampos Tzoulis retweetledi
The Science of Parkinson's
The Science of Parkinson's@ScienceofPD·
Christian Dölle & @chtzoulis provide the background & rationale for why NAD augmentation could be a disease-modifying strategy for neurodegeneration; The Phase 3 NO-PARK study in #Parkinsons reports later this year - NOPARK-extension (NCT05546567)=+4 years cell.com/trends/endocri…
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Charalampos Tzoulis
Charalampos Tzoulis@chtzoulis·
I have decided to leave X, as its current direction no longer aligns with my commitment to science and humanistic values. For those who want to stay connected, you can find me on Bluesky: @chtzoulis.bsky.social. Hope to see you there!
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Charalampos Tzoulis
Charalampos Tzoulis@chtzoulis·
Is mitochondrial pathology universal in idiopathic Parkinson's disease? We find widespread mitochondrial pathology in the brain of ~25% of individuals with PD, linked to a non-tremor dominant motor phenotype. Could this be a "mitoPD" subtype? nature.com/articles/s4146…
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Charalampos Tzoulis retweetledi
The Science of Parkinson's
The Science of Parkinson's@ScienceofPD·
Wow! New paper from @chtzoulis & collaborators proposes that idiopathic #Parkinsons can be stratified according to the severity of neuronal respiratory complex I deficiency; They find 2 emerging disease subtypes with distinct molecular & clinical profiles nature.com/articles/s4146…
The Science of Parkinson's tweet mediaThe Science of Parkinson's tweet mediaThe Science of Parkinson's tweet media
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Charalampos Tzoulis retweetledi
Gonzalo S. Nido
Gonzalo S. Nido@GonzaloNido·
First Brain Brunch of the year, with @chtzoulis giving an overview of #Parkinsons. Looking forward to a 2024 full of good science!
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Mons, Norway 🇳🇴 English
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Charalampos Tzoulis retweetledi
Christos Proukakis
Christos Proukakis@proukakis·
(1/3) Preprint from the lab: comparison of three commercial methods for single cell whole genome amplification for detection of large somatic copy number variants. We compared the well established PicoPLEX with two clever variations of multiple displacement amplification (MDA)...
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Keşfet

@CureParkinsonsT @UiB @ScienceofPD @GonzaloNido @haukeland_no @erna_solberg @tonewtroen @Neuromics