E² by Ari Massoudi

Anthropic is hiring life science researchers.  This is very important: applying AI to protein designs, genomics, and advanced cellular simulation... The once thought-to-be 'untreatable' diseases are poised for a reckoning of breakthroughs.

@louisnandre Episteme is a beautiful name by the way! :-)

Read more in our announcement post here: epistemescience.substack.com/p/introducing-…

Today, we're announcing @episteme, a new type of R&D company that recruits exceptional scientists to pursue high-impact ideas. Science isn’t bottlenecked by the availability of talent, but by places where they can do their best work. Scientific progress has driven human flourishing: extending lifespans, lifting billions from poverty, and expanding our understanding of the universe. But history is littered with transformational ideas that were overlooked in their time. That problem is still acute today: too much promising talent remains uncultivated, and remarkable ideas die in the lab or are filtered out by misaligned incentives. Today, scientists face suboptimal paths for translating their research into impact: academia is famously risk-averse and incentivizes publications and winning grants vs. translational research. Industry is too often focused on short‑term incentives. And startups lack the substantial capital, expertise, and complex infrastructure needed to deliver long-term scientific progress. On top of that, recent funding cuts in the US mean the overall supply of ideas is decreasing. Put together, the global scientific production system is operating at a fraction of its capacity. How Episteme operates is different: we identify great scientists who can meaningfully benefit humanity, but who aren’t supported efficiently within traditional institutions today. Researcher by researcher, we work with them to determine the bespoke resources, operational support, and environmental conditions to execute on their research. We bring them together in-house, and provide those resources to ensure that their breakthroughs are deployed for real-world impact. We’ve already assembled an amazing team of operators, ranging from the Gates Foundation, DeepMind, ARPAs, DoE – just to name a few – and researchers who are pursuing important problems across physics, biology, computing, and energy. Our team has spoken to hundreds of researchers across disciplines and geographies to understand the limitations they’re facing and what can be done better, and designed Episteme for them. We’re backed by individuals like @sama, Masayoshi Son, and other long-term partners who share our mission of enabling ambitious science for tangible human impact. About me: I started working as a researcher 9 years ago, on problems ranging from AI-driven drug discovery to developing brain-machine interfaces. It was that experience that led me to realize that so many scientists with great potential to change the world don’t have access to opportunities equal to their capacities. @sama and I believe that much better science should happen for humanity, and that a new engine is needed to support that. We decided to cofound Episteme together, and I am incredibly grateful for Sam’s unwavering support as a thought partner and founding investor. Our conviction is that by supporting the right people with the right incentives, we're set to generate breakthrough discoveries to benefit humanity. We cannot rely on the course of history to shape scientific progress; we need to proactively shape the system by supporting the most talented people with the right resources and incentives.

The technological acceleration spells doom for established businesses

🚀 Attention deeptech founders: Your intellectual property strategy isn't complete without strong branding.

Once I assisted in a presentation (by a Technology Transfer expert from the Fraunhofer Institutes) about the differences between French vs German Tech Transfer (organisations and practices).

What if Jane, the AI Pharmacist, Designed a Drug That Could Rejuvenate You?linkedin.com/pulse/how-scie…

Would you choose Dr. Jane as a Supervisor for your PhD studies? 👇👇👇 linkedin.com/pulse/dr-jane-…

Thanks to AI ✅ Chemists: jobless ✅ Pharmacists: jobless ✅ Physicians: jobless Who's next? Biologists? ... Nah, I don't think so. We can always quit our labs and go back to a forest and watch days-long chimpanzees doing monkeying.🙊 🙈🙉🐵 linkedin.com/pulse/200-year…

Even With Less Fingers Than You, Dr Jane is Far More Productive Than Y'all.🤠 While Artificial Intelligence is Finding Miracle Drugs, Organic Scientists Slack Off and Snooze linkedin.com/pulse/how-arti…

Only the chosen ones will be accepted to join Elysium. Will you be one of them? Read this to know it ... 👇👇👇 linkedin.com/pulse/become-i…

Have you secured your ticket for the spaceship bound for Elysium? Hurry up! There are only a few left! 👇👇👇 linkedin.com/pulse/how-life…

The plant kingdom 🌱 is a treasure trove of life-extending molecules 🧬. But finding them takes ages ⏳. Luckily, AI-driven drug discovery 🤖 is here to change the game! linkedin.com/pulse/have-you…

The End of Lottery in Drug Discovery Dr Serendipity: The Real scientist Behind All The Old Drug Discoveries In the 1960s, a chance discovery ignited a revolution in epilepsy treatment.

You know people who have made a ton of money by investing in new drugs. 💰💰💰 And you'd love to be in that game too, right? 🤑 Learn the key points to understand the language of AI drug design startup founders. 👇👇👇 linkedin.com/pulse/11-key-p…

It's technically possible to create Humans with a photosynthesis capacity. Let's see how: 1) We need ovocytes from female donors. 🥚 2) We extract chloroplasts from your favorite green vegetables. 🌳 3) We inject the chloroplasts into an ovocyte. 🥚

"Aliens built the Pyramids, and they offered us AI to discover new drugs to make us immortal beings." - Maître Pims (Only the French can understand this mysterious quote ) 👇👇👇 linkedin.com/pulse/how-anci…

📽️The New Romantic Comedy Not to Be Missed💘 Bob, a brilliant VC, following a spectacular exit and a crazy night in Vegas, gets sick by an antibiotic-resistant infection. Rescued by Dr. AI Jane AI, he realizes ... Read the story 👇👇👇 linkedin.com/pulse/how-dr-a…

The Earth is flat and hollow like Gruyère cheese 🧀. This is a fact! Change my mind🧐 That's not all: Gula, an Ancient Sumerain goddess 👽 gifted us Aspirin 💊 and AI 🤖 Accept the truth once and for all. 👇👇👇 linkedin.com/pulse/how-gula…

Professor Damien Remède, a brilliant adventurer & medical genius, hunts for the elixir of life in the heart of the Amazon. But a rogue AI seeks to exploit his discovery for global domination. A high-stakes race against time and technology begins! 👇👇👇 linkedin.com/pulse/how-famo…

Your brain sucks?🤯 Introducing Dr AI-Jane, your personal at-home psychiatrist ready to heal your mental issues!🤖 Mood swings, mania, depression? Jane diagnoses & prescribes you the perfect pills. Get your Dr Jane right now & bring peace at home 👇👇👇 linkedin.com/pulse/imagine-…