David Bonet

"Point cloud local ancestry inference (PCLAI): continuous coordinate-based ancestry along the genome" New preprint from @alexGioannidis's group looks super interesting! Deep learning to plot haplotypes into continuous PC spaces. Lots to go over. I need to read it more deeply

snputils (snputils.org): A High-Performance Python Library for Genetic Variation and Population Structure biorxiv.org/content/10.648… 🧬💻🧪 github.com/AI-sandbox/snp…

The R binding is live at github.com/frankiethull/i… We're bringing all TFMs, ICLs, LDMs, & LTMs to R 🔥

Excited to share our preprint on iLTM: an Integrated Large Tabular Model! arxiv: arxiv.org/abs/2511.15941 No single technique consistently excels across all tabular tasks. iLTM addresses this by integrating distinct paradigms in a single architecture: - Gradient Boosted Decision Trees (GBDT)-based embeddings - Robust preprocessing with random feature projections - A meta-trained hypernetwork - Retrieval augmentation with Soft Nearest Neighbors @d_bonet @marcal_cc @alexGioannidis (1/N)