daCostaLab

Excited to share our latest collaborative effort posted on bioRxiv. The combined power or single-molecule structure and function... All in one package! Thanks to all our great collaborators! biorxiv.org/content/10.110…

Check out our latest work published in Nature Communications. Congrats to @Christian_Tess1 , @EmlawJohnathon, and Mich for all the hard work. nature.com/articles/s4146…

Check our latest work in Communications Biology! Big shout out to all our collaborators @JohnBaenziger1 @Chica_lab, and Jesús and Michael, in particular, for making it happen! nature.com/articles/s4200…

This week we’re reading a #preprint by Christian Tessier, @CorriedaCosta and colleagues @daCostaLab on the muscle-type nicotinic acetylcholine receptor: biorxiv.org/content/10.110… 1/4

Check out Christian's latest work posted on bioRxiv! Derepression masquerades as activation in a pentameric ligand-gated ion channel biorxiv.org/content/10.110…

Excited to share our latest work published in eLife... Final and HTML versions now available! doi.org/10.7554/eLife.… @eLife

Ancestral acetylcholine receptor β-subunit forms homopentamers that prime before opening spontaneously doi.org/10.7554/eLife.…

"The Biophysics of Ligand-Gated Ion Channels: From Structures to Drug Discovery" preliminary program online. Join us in person or via livestreaming! event.fourwaves.com/jointbsc2022iu….

@Bowie_Lab @daCostaLab @corriedacosta The biophysics of ligand-gated ion channels: from structures to drug discovery!

Three profs, daCosta, Campbell-Valois and Shuhendler, have built the bioGARAGE to enhance student experience. Support the bioGARAGE with a gift through Giving Tuesday. See here: Faculté des sciences app.simplyk.io/fr/peer-to-pee… #GivingTuesdayCA #uOttawa #uOscience #bioGARAGE

uO Giving Tuesday campaign is underway! Support bioGARAGE and the next generation of Synthetic Biologists here: app.simplyk.io/en/peer-to-pee…

@sgpweb Not quite a real time machine, but we're working on it!😉 pnas.org/content/118/7/… cell.com/structure/pdfE…

A4. I'm excited to see more #ionchannel #structures, as well as advances in #molecular #simulations that will help us to understand the physical mechanisms that underlie electrical signaling. Also a time machine⏲️would be cool. Is that too much to ask?😉

Check out our latest work in PNAS combining single-channel recordings and evolutionary biochemistry. @uOttawaCHM @CCSB_uOttawa @MusgaardLab pnas.org/content/118/7/…

Check out our latest paper: "Contingency between historical substitutions in the acetylcholine receptor pore". Congrats Johnathon! pubs.acs.org/doi/10.1021/ac…

dacosta]:[lab went curling today with @BoddyLab and @MolMedLabuO. Lots of spills, thrills, and chills. Look familiar? #pentameric #ligand #gated #ionchannel

Congrats Blair, Christian, and Mat on publishing a simple and useful tool or improving single-channel burst analysis. authors.elsevier.com/sd/article/S23…

BREAKING NEWS: The Royal Swedish Academy of Sciences has decided to award the #NobelPrize in Chemistry 2018 with one half to Frances H. Arnold and the other half jointly to George P. Smith and Sir Gregory P. Winter.

Grass roots Molecular Biology: uottawa.ca/give/lego-your…

Benefits to being in a Chemistry Department... Thanks to @BoddyLab for "Periodic Table of the Cupcakes". #ediblelements #cupcakes

Check out our 1st paper describing an Evo. Biochem. approach to AChRs! cell.com/structure/full… #ionchannels #ASR #proteinevolution #AChR