Daniel Hilger

@valendraica Congrats Jean-Paul ! I always love structures of native complexes 😍

This was a highly collaborative work between multiple labs, performed by a talented grad student in the Armache and Murakami labs, Natalie Smith. Thank you to all the authors for their incredible work!

We did a thing... We purified native transcriptional complexes from Drosophila embryos, obtaining +/- stalk Pol II elongation complexes, native nucleosomes, as well as a nucleosome elongation complex. For more details please check out: doi.org/10.1101/2025.0…

New review article in @NatRevDrugDisc on Functional Dynamics of GPCRs, based on discussions from a great CECAM GPCR meeting. Congrats to Vittorio, Paolo, and all the other coauthors! #NMR #NMRchat #Ack1" target="_blank" rel="nofollow noopener">nature.com/articles/s4157…

@CorneliusGati @USC @USCDornsife That’s great work. I remember discussing this some years ago with some folks from the Kobilka lab and we were joking that the receptor would break in half 🤣

Excited to share our work on GPCR antagonism: Contrary to popular belief, inverse agonists can bind to and act via GPCR:G protein complexes. We show this at kappa-opioid receptors by cellular, radioligand binding and cryoEM studies. A 🧵: @USC @USCDornsife nature.com/articles/s4158…

We are recruiting a young researcher to join our dynamic lab at UCSF - this is a great opportunity if you would like to get some research experience before graduate or medical school! aprecruit.ucsf.edu/JPF05305. Please RT!

@MiriamStoeber Congrats Miriam and all the authors! Beautiful study and exciting findings.

When you get an Aston Martin in return for a favor, you know you have great colleagues !!!🤩

Are you interested in #GPCR / #Gprotein signaling and #biosensor development? Then please apply for this open #PostDoc position in my new Emmy Noether Research Group @Uni_MR! stellenangebote.uni-marburg.de/jobposting/9f7… #newPI

An announcement: The O'Brien lab is hiring!! If you're interested in GPCR structural biology, dynamics, and/or drug discovery, see posting for postdoc position(s) here (apply.interfolio.com/153041) and (NEW!) lab website (evanobrienlab.com) for more. Please share this widely!!

@jjanetzko Obviously a membrane protein

Getting ready for Ni batch binding

Please reach out if this is of interest and stay tuned for more!

📢I have open PhD student and Postdoc positions to join my #EmmyNoether lab to decipher how #GPCR-specific signaling is achieved by heterotrimeric #Gproteins! ‼️Interested in developing novel biosensors💡 that reveal yet invisible states and processes🔍? ➡️DM or email me📨‼️

Please RT: Our department @Saar_uni is looking for a new group leader in #biochemistry, #membrane, #organelle #biology. Great opportunity for early career young scientists in a young, vibrant and supportive environment. Send applications until 11.Aug 2024. uni-saarland.de/fileadmin/uplo…

My lab has multiple openings for those interested in doing some very cool science in beautiful Colorado! Research assistants (tech/lab manager level): cu.taleo.net/careersection/… Postdoctoral fellows: cu.taleo.net/careersection/… DM or email me if interested and 🙏 share broadly 🪃

@evan_s_obrien @Nature Congrats Evan !

Excited to share our recent work on the discovery, characterization, & implementation of a new opioid receptor negative allosteric modulator, out in @Nature today! nature.com/articles/s4158…

If you have a background in chemistry, biophysics, cell biology and ambitious for research we are searching for you!! Apply to do your PhD with us! jobs-sf.ukmuenster.de/job/UKM-PhD-St…

@Uni_MR We will dive into the fascinating question how so many #GPCRs expressed in the same cell can activate the same #Gprotein but induce distinct signals and cellular responses! Interested? Please reach out ✉️ uni-marburg.de/en/prfolder-en…

@HSchihada @Uni_MR Congrats again Hannes, well deserved !

I'm extremely honored and grateful to be awarded the competitive Emmy Noether Program to establish my own research lab @Uni_MR! I'd like to thank all my past and present mentors and colleagues for the support I've received. Let's get this started #GPCRs #Gproteins #biosensors!

@emeKato Congratulations Hideaki ! Make sure you have a scroll button on your homepage for the awards section 😉

有り難いことにIUPAB (International Union for Pure and Applied Biophysics) から賞を頂けることになりました。 自分達の研究が国際的組織から評価して頂けたというのは素直に嬉しいです。 6/24より始まるIUPAB2024でlectureをすることにもなったので、学会に参加される＆お時間のある方はぜひ。