Daniel Kunz

From @davisjmcc, @YuanhuaHuang, @OliverStegle and Teichmann lab: Cardelino leverages variant information from single-cell RNA-seq data for inferring clonal tree configuration and mapping cells to their clone of origin. nature.com/articles/s4159…

For the first time, the highly dynamic cellular landscape of the human thymus has been charted across a lifespan, according to a new Science report, which may be useful in developing future T-cell therapeutic strategies. ($) fcld.ly/kc9mg52

Our work on T-cell lineage commitment and TCR recombination in the native thymic microenvironment across human lifespan is online! Fantastic team led by @park_jongeun, Sarah Teichmann, @Muzz_Haniffa and @taghon_t science.sciencemag.org/content/367/64…

Registration is open for #QG19 on 10th June 2019 at the Francis Crick Institute, London! See website for full details: quantitative-genomics.com

Cardelino: Integrating whole exomes and single-cell transcriptomes to reveal phenotypic impact of somatic variants biorxiv.org/cgi/content/sh… #bioRxiv

Fast Batch Alignment of Single Cell Transcriptomes Unifies Multiple Mouse Cell Atlases into an Integrated Landscape biorxiv.org/cgi/content/sh… #bioRxiv

How can single-cell methodologies unravel immune cell fates?Check this mini review by @danieljkunz , me and @KylieReneeJames to learn about cell fate tracking, trajectories and more! @FrontImmunol frontiersin.org/articles/10.33…

Interested in new insights into alternative splicing at the single-cell level and how DNA methylation plays a so far underappreciated role? Take a look at our new bioRxiv preprint: biorxiv.org/content/early/… Great collaboration with @mjbonder @OliverStegle @davisjmcc @StatGenomics

SCI{Phi}: Single-cell mutation identification via phylogenetic inference biorxiv.org/cgi/content/sh… #bioRxiv

Our methods (with @OliverStegle ) do detect spatially variable genes and perform expression based histology are now published in Nature Methods! nature.com/articles/nmeth…

Well folks, this is how benchmarks are done. Wow. twitter.com/biorxiv_bioinf…

Our manuscript is now out in Nature Physics: Universal scaling behaviour of clone dynamics during tissue growth. Highlights emergence of core concepts of statistical physics in an unexpected context and implications for stem cell biology. nature.com/articles/s4156…

Posters, short talks and long talks open for Masters, PhD students and postdocs --> quantitative-genomics.com

We have updated our SpatialDE paper - biorxiv.org/content/early/…, largest addition is "automatic expression histology" which finds patterns defined by co-expressing genes with a GP mixture model.

1/8 Our latest work on the role of genetic heterogeneity in clonal evolution is published! @sangerinstitute @Cambridge_Uni @ircaninstitute twitter.com/CellReports/st…

Our new method do detect spatially variable genes together with @OliverStegle is out. Software and all analysis at github.com/teichlab/spati… twitter.com/biorxivpreprin…

Letter from Crick and Watson to Erwin Schrodinger dated 12 Aug 1953 re: What is Life? & the impact on their careers