M PREMKUMAR

🇮🇳 Real-world data from >1000 patients with MASLD/MetALD MRI-PDFF phenotyping + 🧲 MRE anchor 🔍 Key takeaways: ✔️ Similar CMRF & AF burden ✔️ FIB-4 & NFS perform well ❌ APRI underperforms 💡 Simple NITs even for MetALD @AnandVKulkarni2 @DrMaheshgoenka link.springer.com/article/10.118…

🧵NEW STUDY PUBLISHED Our DiaFib-Liver Study is now published in @LancetRH_SEAsia. The largest-ever real-world survey of liver fibrosis in type 2 diabetes from any low- or middle-income country. 9,202 patients. 82 doctors. Pan-India. 🇮🇳 🔗 authors.elsevier.com/sd/article/S27…

#Fibrosis prevalence across clinical subgroups: Highest: CAD (33%), eGFR <60 (33%), Obesity (32%), Dyslipidaemia (30%) Even without obesity: 19% Dashed line = overall prevalence (26%). No difference by sex or hypothyroidism. Fibrosis is widespread across ALL subgroups.

@anjan_dhar6 @IJG_Journal @UshaPGIMER @drvishal82 @drsridhars @SChandanMD @BabuPMohan2 @Samanta_JayPGI @elhence_anshu @ibdseb @amolbapaye @ZaheerNabi8 @miNitinjagtap @GKochharMD link.springer.com/journal/12664/…

@docMPK @IJG_Journal @UshaPGIMER @drvishal82 @drsridhars @SChandanMD @BabuPMohan2 @Samanta_JayPGI @elhence_anshu @ibdseb @amolbapaye @ZaheerNabi8 @miNitinjagtap @GKochharMD Please send the link to the journal, thank you.

The Purple edition for the special issue of @IJG_Journal : WOMEN and GASTROENTEROLOGY Out now! A huge effort by the team to compile this beautiful collection of articles @UshaPGIMER @docMPK @drvishal82 @drsridhars #GITwitter

*New Issue Alert* The special IJG Women and Gastroenterology March-April issue (Volume 45, Issue 2) is online. Please have a look: link.springer.com/journal/12664/… @IJG_Journal @docMPK @drvishal82 @drsridhars @DrAnuraagJ @giri_gutnliver @UshaPGIMER

Gastro-intestinal infections and stewardship practices—A call for action to practising GI professionals Rohit Gupta et al link.springer.com/article/10.100…

@IvaKosuta Thanks Iva!! Hope to see you work with us on the next one.🗺 prospective data needed.

New study challenges albumin use in cirrhosis + septic shock. POCUS-guided resuscitation showed NO mortality difference between 20% albumin+BSS vs BSS alone at 28d (36.5% vs 31.8%) or 90d. The key predictor? Cirrhotic cardiomyopathy (CCM), not fluid choice. 🫀💉

@giri_gutnliver @KIMSGastro @hsid_h @RoyAHep @drsridhars @AnandVKulkarni2 @DrAnuraagJ @KailashKolhe @drgauravkhatana Congratulations Giri

All that Gastro & Liver...Happy to share the publication of 11 manuscripts (7 original articles, 2 systematic review/meta-analysis, 2 review) in the month of February with 9 from @KIMSGastro & 2 from KEM... Extremely thankful to all my seniors and colleagues for their support...

MUST-READ REVIEW Gastrointestinal cancers in women: The role of sex hormones by Amit Yadav & Prof Usha Dutta @UshaPGIMER #WomenGI #GItwitter link.springer.com/article/10.100…

On the occasion of International Women's Day We released the special issue of @IJG_Journal on women and gastroenterology. It is purple to signify women empowerment #GITwitter #WomensDayEveryDay

Please do read and share articles from the Special Isdue on Women in Gastroenterology.... Physicians and Patients. Special thanks to all contributors.@JCEH_Hepatology @IvaKosuta @pummy92 @MaiwallRakhi @SwetaRose3 @ShubhraMishra91 @LisaVWMD @manasa_alla @drvishal82 @drsridhars

kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2… For liver POCUS aficionados. @JCEH_Hepatology @hepocus @RoyAHep @manhalizzy @KavishPatidar11 @RohitMehtaniDM @AnandVKulkarni2 @KoraAbhi @IvaKosuta @DivyaveerSSNeph @pummy92 @MaiwallRakhi @stevenbollipo @giri_gutnliver @drkeithsiau @SakkarinC @Apichatka

🆕 @INASL_Liver Consensus provides practical guidance on “difficult-to-treat AIH” 🔹 Acute AIH 🔹 Cirrhosis 🔹 Overlap syndromes & drug-induced AIH 🔹 Pregnancy, paediatric & post-LT AIH, comorbidities 📖 Read now in JCEH jcehepatology.com/article/S0973-…

Recompensation in ALD-20% (large multicenter data from India) ✅higher in DC without AAH ✅Linked to better survival Each additional month of abstinence -3% higher chance of recomp. 7% re-decomp 17% decomp further (who did not recomp first) ghadvances.org/article/S2772-… @BavenoCoop @ReibergerThomas @JimmyLaiCT @RoyAHep @ggarciatsao @ebtapper @juanpabloarab @TCotterMD #LiverX

💬 In cirrhotic patients with #HCC, how do you approach thrombotic risk assessment? 🔘 Routine screening 🔘 Case-by-case 🔘 Mainly after PVT occurs 🔘 No standardized approach #LiverCancer #Hepatology @manhalizzy @rav7ks @MichaelAlbertMD @docMPK @perillo_prazole @katiewiskar

jcehepatology.com/article/S0973-… 🧵3..Assessment of Shock Phenotypes and AKI phenotypes is the best strategy for management of the hepatocardiorenal axis. POCUS is the simplest and safest tool in hepatology practice..🎯 @ajay_duseja @AnandVKulkarni2 @drnipunverma @salvatore_piano

Point-of-care ultrasound (POCUS) guided pragmatic fluid and albumin resuscitation and hemodynamic monitoring in Cirrhosis and Septic Shock -🧵1 jcehepatology.com/article/S0973-… Comments Welcome! @RoyAHep @hepocus @KavishPatidar11 @kumarrahul0204 @ebtapper

🧵2 Restrictive and Effective POCUS guided volume resuscitation works best. Shock is a spectrum...Phenotypes are between Fluid responsive to circulatory failure. ✅️⏳️Time based perfusion targets reduce mortality. Assessment of CCM and Fluid challenge ➡️ 'cardiac reserve'

The Pancreas edition of @IJG_Journal is out !! A wonderful compilation of articles!