Dong Yang

Excited to share our work! We uncover a top-down circuit that drives fragmentation of feeding behavior—a system that can be captured as stochastic perturbations within an attractor network. Many thanks to my advisor @liye_tsri and collaborators @Antihebbiann and @CurioNeuro!

Postdoctoral fellowship available in structure guided drug discovery in @RothLabUNC Please RT

Proud neighbor retweeting the recent Science paper by Marco Uytiepo, Anton Maximov et al on multi-synaptic boutons underlying memory. science.org/doi/10.1126/sc…

The indiscriminate and ill-conceived slashing of indirects by the @NIH yesterday must be amended if want to restore America’s leadership role biomedical research. 15% simply isn’t enough for institutions to provide the basic infrastructure needed to run a successful lab. I say this as someone who has been and remains deeply critical of the NIH, its funding system and of the ways universities are structured and spend money. We would all benefit from a genuine reexamination of how and to what @NIH funds are allocated, and I remain optimistic that once the dust settles and new NIH leadership is in place that this is what will happen and this hack job by people who don’t understand or care about research will be forgotten. And I’m sorry but I can’t help but laugh at the people who are demanding a full-throated defense of the current indirect levels. Nearly every PI I’ve known for my entire career has complained about excessive indirect rates. This is mostly because, despite their importance, even most PIs haven’t bothered to actually understand them, and because they don’t FEEL that universities are actually spending the money to support their research. Whether they are or not nobody really knows because in the typically Byzantine maze of university budgets it’s often very hard to figure out. There are also lots of actual shenanigans that go on especially at places with the highest indirect rates to use funds to build out the institution and increase its power rather than to directly support funded research projects. And anyone who says administrative bloat at universities isn’t real and partially fueled by indirects is either blind or part of the bloat. So let’s get organized to have an actual constructive response to this firebomb. Scientists need to advocate for what is best for research - and we have to do it ourselves because the institutions that claim to represent us - universities and scientific societies in particular - have their own goals that often do not align with ours. We also have to remember that grants are not an entitlement. We are not owed anything. If we want to continue benefiting from the public support we have always enjoyed, we have to show the public and their representatives - even ones we might not always agree with - that we’re spending their money wisely.

Check out our latest issue: cell.com/neuron/current Spring on its cover, memory and a touch of music in its pages with reviews on ensembles and the thalamus in cognitive control, and a Q&A with Joseph LeDoux, and more!

@ElissaWelle Thanks again for introducing this work.

A new technique to track when neurons switch off, crucial for brain health and disease understanding. This innovative approach, using PDH protein changes, could revolutionize neuroscience research. neurosciencenews.com/neural-inhibit…

In a new @NeuroCellPress study, @liye_tsri & @JohnRYatesIII have developed a new technology to track brain cell inhibition after activity bursts. The method aids in understanding normal brain functions and disorders like depression, PTSD, and Alzheimer's. ow.ly/woXh50QtHnH

Inverse Activity Marker is now published in @NeuroCellPress Incredible team and many collaborators. cell.com/neuron/fulltex… Major updates from preprint. Don't hesitate to reach out. We are eager to know how it works in the field and to help. Lab protocol on our website.

@liye_tsri @NeuroCellPress 🎊

Phosphorylation of pyruvate dehydrogenase inversely associates with neuronal activity cell.com/neuron/fulltex…

My lab is looking for a research technician and postdocs. theaugustinelab.org/positions Application link: employment.ucsd.edu/lab-assistant-…. Please help spread the word.

@ZhengyuanP @liye_tsri @kevansf congrats 🎉 Dr. Pang

Five years fly past like a dream. Can hardly imagine it’s my defense day. Thanks everyone for coming and especially my advisor @liye_tsri . It’s a fascinating scientific journey. Thanks @kevansf for coming here and it’s such a great day to remember.

@vinnyaug1 @Nature @JonnyLovelace @JingruiM @Saurabh41288505 congrats!

Excited to share the first paper from our lab published @Nature led by extraordinary co-first authors @JonnyLovelace and @JingruiM with help from talented @Saurabh41288505. rdcu.be/dp17I

Super excited to share our latest work @Nature, led by Neeraj Lal. Mammals, including humans, eat more in the cold (e.g. winter). Through metabolic, behavioral, and whole-brain circuit screens, we found a tiny nucleus (Xiphoid) gating this behavior. nature.com/articles/s4158…

@CRI_UTSW @ShangMa5 @WelchFoundation congrats! @ShangMa5

.@ShangMa5 was recently awarded a grant from the @WelchFoundation to study how cells sense and process mechanical stimuli in human diseases. This funding will help his lab identify novel “mechanosensing” PIEZO-dependent pathways as promising drug targets. Congrats, Ma lab!

An excellent opportunity to manage our Nikon Center of Excellence microscopy facility at the Dorris Neuroscience Center within Scripps Research in beautiful La Jolla/San Diego just opened up. Please use the link below to apply. Please RT! recruiting2.ultipro.com/SCR1003TSRI/Jo…

We are recruiting a postdoc to investigate the role of DDR pathways in driving viral-induced microcephaly and other neurodevelopmental disorders. Come join us in sunny San Diego to work on this fascinating project that is well underway. linkedin.com/jobs/view/3324…