Mohamed Donia

@NadineZiemert This is a great place to do science, with an awesome PI, and working on a super cool project. What a complete package!

@wildtypeMC @nabroderick @conTAMInatedsci @KlassenLab @baym @ChemSynthBiol @TraxLab @racheljdutton @DrAnneCarpenter @tera_levin @sharpnath In my opinion, if we break open this black box and clearly show young scientists what is actually expected at this tricky career stage, it will be easy to set personal goals and get ready. Maybe this is where we should start.

What should have been on your BECOME A PI checklist at t -2 years to job market? I'm trying to plan as rationally as best I can. @nabroderick @conTAMInatedsci @KlassenLab @baym @ChemSynthBiol @TraxLab @racheljdutton @donia_lab @DrAnneCarpenter @tera_levin @sharpnath pls RT

@wildtypeMC @nabroderick @conTAMInatedsci @KlassenLab @baym @ChemSynthBiol @TraxLab @racheljdutton @DrAnneCarpenter @tera_levin @sharpnath The worst thing about this process is that there is no information out there about what it actually entails to be a PI. Coming out of the post doc, scientists start almost completely blinded to what they will have to do, which includes many things they have no prior training for.

@DevlinLab Awesome work from @DevlinLab, demonstrating the power of applying innovative chemical approaches to microbiome research.

Our first pre-print! Check it out:

@AnneOsbourn1 Amazing piece of work! Congratulations, Anne.

A specialized metabolic network selectively modulates Arabidopsis root microbiota science.sciencemag.org/content/364/64…. A fantastic collaboration with Yang Bai’s lab, and sterling work by the inspirational Ancheng Huang. Part of the JIC/CAS alliance cepams.org/home/

A great tool from the awesome @NadineZiemert ‘s lab.

Please RT: I'm looking for an awesome postdoc to come and help us define how exposure to environmental pollutants disrupts the gut microbiome's contribution to behavioral development. Learn more at sharptonlab.cgrb.oregonstate.edu/?q=node/14 or contact me with questions.

Check out @Melissa_Galey preprint, collaborative work w/ @JBurdetteLab funded by @UIC_CCTS & laid the ground work for our recent @RCSA1 grant with @JudithTTSu : biorxiv.org/content/10.110… This preprint shows MALDI-TOF #MassSpec is promising for following #OvarianCancer in vivo

@tjsharpton What a coincidence! Let me give you the view from the opposite coast: sitting in my office at 9 pm, struggling with a complicated microbiome analysis problem & thinking who would be a great person to consult with or to have them take a look at the solution; let’s poke @tjsharpton

Sometimes the internet is creepy. I was discussing @donia_lab's excellent work with a student in my office today. Two hours later, guess who now follows me on Twitter. A spooky but welcomed coincidence (I presume).

Thanks, everyone. It is by the support of this extremely kind community that we survive day to day. There are so many people who helped us here, from ones who helped us get samples when we couldn’t travel, to others who allowed us to use their enabling equipment. 1 M thanks.

Sponges, the oldest living animals, dedicate one of the few types of specialized cells they harbor towards housing intracellular symbionts for the production of complex defense chemicals, which is pretty much all these symbionts do.

If you are interested in learning more about our recent study in marine sponges, please check out this piece by Dai Tianero, the amazing post doc who led this work: Cellular reservoirs of defensive symbionts in sponges naturemicrobiologycommunity.nature.com/channels/346-b… #behindthepaper

@3rdreviewer @markjmandel Agreed!

@donia_lab @markjmandel Obviously they have had less phenotypic change since our common ancestor, but this does not mean that current species represent ancestral states.

@3rdreviewer @markjmandel Thanks for the catch -- meant "ancient species". I will fix shortly.

@donia_lab @markjmandel There is no such thing as an “ancestral organism.” Perhaps there’s a better term for what you want to say here?

I am asking this genuinely. What is the best use of Twitter for the scientific community: 1. learn about other work in your field, 2. publicize your own work, travel, paper, or grant, 3. voice your opinion about scientific or other issues, 4. share usually untold experiences?

@ajlinklab @Princeton @BrianOBachmann Thanks @BrianOBachmann for an inspirational talk today — I wish we could all be as brave as you are in jumping into these uncharted territories!

Great seminar today in @Princeton CBE from @BrianOBachmann!

@BrianOBachmann Looking forward to having you here @BrianOBachmann, and to learning more about the awesome NP science coming out of your lab. I hope you will enjoy the snow storm!

Very grateful to have worked with an amazing team of scientists on this project throughout the last 3.5 years: 6 people from 6 countries! I am also very thankful to the continuous support of remarkable colleagues at @Princeton & mentors throughout the journey of a #YoungPI 6/6

We hope that our systematic screen will be a resource for the @US_FDA, a starting point for many follow-up investigations, and a motivation for including microbiome studies in future drug development. 5/6

Here we go world, our first @donia_lab preprint and manuscript to hit the web: @biorxivpreprint @biorxiv_micrbio "Systematic mapping of drug metabolism by the human gut microbiome" biorxiv.org/cgi/content/sh… -- more details in this thread 1/6