Ayush A

Takayasu arteritis is a large vessel vasculitis predominantly affecting young women. Subclavian steal phenomenon can occur by the predominant affliction of the left subclavian artery (before left VA origin). George et al has described one such case. Link: 10.4103/aian.AIAN_25_22

Heerfordt-Waldenstrom syndrome (HWS) is a tetrad of fever, parotid enlargement, facial palsy and anterior uveitis. HWS is rare but considered pathognomonic of sarcoidosis. @drayushagarwal has described one such case. Link: 10.4103/aian.aian_1014_25

MERS (Mild encephalopathy with reversible splenial lesions) is commonly triggered by infections. @drayushagarwal et al described a rare case of enteric fever associated with MERS which also had bilateral dentate nucleus involvement @Divyani_Garg. Link: 10.4103/aian.aian_688_25

The presence of mastoid involvement on MRI is not sine qua non of associated middle ear infections & should raise possibility of CVT. Srivastava et al describe higher thrombus burden in CVT increases likelihood of mastoid signal change @drayushagarwal @vishnuvy @Divyani_Garg

Kikuchi disease (KD) is a rare condition causing fever with lymphadenopathy. Biopsy characteristically reveals histiocytic necrotizing lymphadenitis. @drayushagarwal @Divyani_Garg reported a case of autoimmune limbic encephalitis associated with KD. Link: 10.4103/aian.aian_498_24

OCEANIC STROKE trial has proven that Asundexian (factor XI inhibitor) 50mg over and above best medical management was more effective and safe in patients with non cardioembolic acute ischemic stroke #ISC26

Cilostazole should be the antithrombotic of choice for treating adult patients with moyamoya disease #ISC26

Just in at #ISC2026: CHOICE2 trial revealed that additional intra-arterial thrombolysis after EVT led to an increased proportion of patients with excellent functional outcome (mRS 0-1) at 90 days with no safety concerns

Optic neuritis is common in Multiple Sclerosis. Rohan Mahale et al report a case of granulomatous panuveitis causing vision loss in MS emphasising MS consideration in patients with B/L uveitis. Link: 10.4103/aian.aian_356_21 #MS #MultipleSclerosis

"Zuckerguss sign" describes leptomeningeal spread of tumour cells which appears as diffuse enhancement on contrast MRI --> similar to sugar coating on a cake. Dr Jakkani et al describe this sign in the cerebellum with a gastric adenocarcinoma. Link: 10.4103/aian.aian_535_21

Coeliac disease (CeD) can present with thrombotic complications. @drayushagarwal presented a case of CeD with CVT as its initial manifestation, highlighting its pathophysiology @drmeenachandu @Divyani_Garg @govindmakharia #Coeliacdisease #CVT Text link: 10.4103/aian.aian_635_25

Akin to intractable hiccups, NMOSD can rarely present with intractable yawning. Dr Saroja et al present one such case. Link to article: 10.4103/aian.aian_813_25 #NMOSD #areapostrema

GFAP astrocytopathy is an autoimmune neurological disorder. MRI brain reveals distinctive periventricular radial and linear contrast enhancement. Dr Ajay Garg et al published the characteristic imaging findings of this rare disorder #GFAP @savyasachijain journals.lww.com/annalsofian/fu…

#STROKE Images: HIV-associated extracranial aneurysmal vasculopathy can occur in an immunocompetent individual with well-controlled HIV. 🩸 ahajrnls.org/3Lf4Kmf @Divyani_Garg @Farsana @drayushagarwal

Alexander disease is a leukodystrophy caused by GFAP gene mutations. Adult-onset presenation: progressive spasticity, pyramidal weakness, and brainstem features. Classical imaging finding -> tadpole brainstem atrophy. Dr Lulup et al present one such case. 10.4103/aian.aian_402_24

@aditya_gan3500 @AnnIndAcadNeur @Divyani_Garg It is being done under some faculty research projects at present

@AnnIndAcadNeur @drayushagarwal @Divyani_Garg Just one question Is triplet primed PCR for DRPLA done at AIIMS New Delhi?

DRPLA causes cognitive impairment + refractory epilepsy in children and ataxia in adults. It is a CAG repeat disorder showing anticipation. @drayushagarwal et al showed these phenomenon in 3 successive generations in a family. @Divyani_Garg #DRPLA #ataxia journals.lww.com/annalsofian/fu…

Chronically occluded carotid stumps can rarely lead to recurrent strokes. --> Carotid Stump Syndrome (CSS). Dr Swati described one such case along with the possible stroke mechanisms in CSS #CarotidStumpSyndrome #LVO pubmed.ncbi.nlm.nih.gov/39172080/

The presence of diffusion restriction on MRI may portend poorer prognosis in patients with Wilson's disease @Divyani_Garg @drayushagarwal @rajan_roopa @achalaiims. Full text published in @AnnInnAcadNeur link: journals.lww.com/annalsofian/fu…

Patients with well controlled HIV, on ART may occasionally develop an extracranial aneurysmal vasculopathy @StrokeAHA_ASA @Divyani_Garg @achalaiims #vasculitis #HIV. Read here: ahajournals.org/doi/10.1161/ST…