Matthew Blakeley
209 posts

Matthew Blakeley
@drmpblakeley
Structural Biology using X-ray and neutron crystallography. Responsible for LADI-III & DALI @ILLGrenoble, previously @EMBLGrenoble @OfficialUoM
Grenoble, France Katılım Ağustos 2009
139 Takip Edilen478 Takipçiler

Beautiful #neutron diffraction data currently being collected from a crystal of an archetypal radical enzyme using LADI-III @ILLGrenoble

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@doescience @ORNL @uthsc @NIH @ILLGrenoble Here is one of the #neutron Laue diffraction patterns from the crystal of the Mpro/BBH-1 enzyme-inhibitor complex collected using LADI-III @ILLGrenoble

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Matthew Blakeley retweetledi

COVID-19 is still with us. Collaborators @ORNL, @UTHSC, @NIH, & @ILLGrenoble used X-rays and neutrons to gain atomic insights into drugs used to treat COVID-19. It could help open pathways to future treatments: energy.gov/science/bes/ar…

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Neutron diffraction from a microgravity-grown crystal reveals the active site hydrogens of the internal aldimine form of tryptophan synthase @ILLGrenoble @ORNLNeutrons cell.com/cell-reports-p…
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@swati_biology @ILLGrenoble @essneutron Here is one of the diffraction patterns from the tests :) @swati_biology @ILLGrenoble @essneutron

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Neutron test beamtime was a success. Thanks @drmpblakeley and Lukas Gajdos for turning my beamtime into a good learning experience.
Exciting times ahead!
@ILLGrenoble @essneutron



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Revealing protonation states and tracking substrate in serine hydroxymethyltransferase with room-temperature X-ray and neutron crystallography nature.com/articles/s4200… @ORNLNeutrons @KovalevskyAY @CommsChem @ILLGrenoble
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Perdeuterated GbpA enables neutron scattering experiments of a lytic polysaccharide monooxygenase pubs.acs.org/doi/10.1021/ac… @ACS_Omega @UniOslo @ILLGrenoble @LSG_ILLGrenoble
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Amazing to recieve this award and sincere thanks to everyone especially at Diamond and beyond who have made this possible! #BirthdayHonoursList
Diamond ILO@DiamondILO
Congratulations to @MartinWalshDLS, Life Sciences Deputy Director @DiamondLightSou, who has been named in the Honours' list to receive an OBE for services to life sciences work. loom.ly/edffUHk
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Matthew Blakeley retweetledi

While visiting our facilities, we discussed ILL's #neutron research programme and its challenges for the future.
We pointed out that there are no technological or administrative obstacles to continuing to operate the reactor well beyond 2033 🚀
#Neutrons4Society
2/2
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Open PhD position in Structural Biology.
NEUTROLECT: Neutron diffraction for deciphering how pathogens interact with human glycolipids.
For more info. please see euraxess.ec.europa.eu/jobs/106463
@ILLGrenoble @Cermav_UPR5301 @UGrenobleAlpes @AnneImberty @LukasGajdos2 @LSG_ILLGrenoble
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Includes an account of how the structure of tryptophan synthase was revealed using neutron diffraction data from crystals grown in microgravity: a journey from Grenoble to space and back again @ChemistryToledo @KovalevskyAY @ORNLNeutrons @ISS_CASIS @ILLGrenoble @LSG_ILLGrenoble

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Matthew Blakeley retweetledi

@DrLaverty describes the analysis of peptide hydrogel drug delivery using small angle neutron scattering (SANS)
@essneutron @ILLGrenoble
#jointILLESSusermeeting2022

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Matthew Blakeley retweetledi

"Hydrogen. The most important, but the most neglected atom."
#NeutronsForEurope #UserMeeting2022
@ILLGrenoble @essneutron

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Matthew Blakeley retweetledi

@LukasGajdos2 presenting results at the @essneutron/@ILLGrenoble users' meeting from his PhD work on a fucose-binding lectin carried out in @LSG_ILLGrenoble and using the LADI-III diffractometer @drmpblakeley. nature.com/articles/s4146…

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Here is one of the #neutron Laue diffraction patterns collected from a crystal of aspartate aminotransferase/pyridoxamine 5'-phosphate using LADI-III @ILLGrenoble

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An N⋯H⋯N low-barrier hydrogen bond preorganizes the catalytic site of aspartate aminotransferase to facilitate the second half-reaction @ILLGrenoble @KovalevskyAY @ORNLNeutrons @ChemistryToledo @ChemicalScience pubs.rsc.org/en/content/art…
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@AnneImberty Congratulations Anne, fantastic news and thoroughly deserved!
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Matthew Blakeley retweetledi

I am extremely happy and honoured to be awarded the Bertaut Prize! Thank you so much! A huge thank you to my great supervisors @AnneImberty @drmpblakeley @vtforsyth and Juliette Devos who supported and guided me in those beautiful PhD years! Thank you all! We will celebrate🥳🕺
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