David Schrijver
57 posts


Cytokines are the master regulators of immune responses. But their systemic administration poorly mimics human physiology👎
We built mRNA nanotech🚀 that lets lymph nodes themselves produce the cytokines exactly where they’re needed👍
Preprint: researchsquare.com/article/rs-809…
Animation👇
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Excited to share a preprint of our work on myeloid cells in pediatric-type diffuse high grade glioma!
🧬In this study we used cyclical immunofluorescence imaging and single-cell spatial transcriptomics to map the tumor-immune microenvironment of pediatric glioma.
bioRxiv Cancer Bio@biorxiv_cancer
Single-cell spatial analysis of pediatric high-grade glioma reveals a novel population of SPP1+/GPNMB+ myeloid cells with ... biorxiv.org/content/10.110… #biorxiv_cancer
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On may 9th, we will host THE FUTURE OF BIOENGINEERING🧪 symposium.
Featuring @ChristineHorejs from @natrevbioeng, @twan_lammers from @RWTH and @mikhailshapiro from @Caltech.
Only 100 spots available & we prioritize @TUeindhoven folks.
Register here: forms.gle/tNgGzG2VUtFkML…

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🔥 just out in @NatureNano! Together with @WillemNANO and our awesome teams @TUeindhoven & @radboudumc we established new #apolipoprotein #nanotechnology for #RNA delivery to the bone marrow🦴!
🗞️➡️ nature.com/articles/s4156…
This has been in the making for 5 years! A 🧵 1/9

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Our new lab’s first🐣 PhD student David Schrijver @dvds94 successfully defended his thesis yesterday🍾
We are Super proud of David🥹 @rvdmnanomeds @TUeindhoven
Thanks to @P_Dankers, @twan_lammers, @francois_fay1 & the other committee members🙏🏼




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Great lecture by @francois_fay1 on #nanomedicine for #sepsis treatment in preparation for @dvds94 defense!

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This one has been in the works for >5 years😱, starting with the ambition to precisely understand polymersomes’ in vivo behavior, which we found to be quite unique!🦄
Team effort by our lab&
@vanhest_lab
@BMEIIsinai
@AbdelmohsenLab
@AviSchroeder
@TUeindhoven
@radboudumc
Nature Nanotechnology@NatureNano
New content online: Polymersomes with splenic avidity target red pulp myeloid cells for cancer immunotherapy dlvr.it/TBJc8t
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🔥 New study on #polymersomes for #immunotherapy just out in @NatureNano! Great effort by @WillemNANO at @radboudumc, @AbdelmohsenLab & @vanhest_lab at @TUeindhoven, @mandyvanleent & Bram Teunissen @BMEIIsinai and @AviSchroeder at @TechnionLive!
nature.com/articles/s4156…
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I’ve seen it. He’s right. @TUeindhoven is one of the nicest places to work at! 👇🏽 cursor.tue.nl/en/opinion/col…
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Did you ever wonder why our marrow is located inside of our *bones*, #MedTwitter? There’s no a priori anatomical reason it should be sited there. Blood cells could form in our spleens & livers, as they do during our fetal lives; or elsewhere, as in some animals. Let’s discuss! /1


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Truly honored to be among the first Netherlands Academy of Engineering fellows nae.nl/fellows
We will be inaugurated on November 13, celebrating #problemsolving through #engineering and pushing #innovation academically & through #entrepreneurship
nae.nl/event/openings…

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🔥🗞️ @WillemNANO Lab preprint just released showcasing our new #apolipoprotein #nanoparticle tech for #RNA delivery to #HSPC developed at
@TUeindhoven, @radboudumc and @biotripnl!
👇
researchsquare.com/article/rs-345…
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The TTxD team pulled off a miracle. Two DRF nanobiologic batches successfully produced in house! At the Pivot Park in Oss. So proud! 🥹
ttxdiscovery.com

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Thanks @JC2_SFNano for inviting @dvds94 and me to talk about our exciting #nanotechnology for #immunotherapy being developed at the @WillemNANO lab at @TUeindhoven and @radboudumc!

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📢 Join us for an enlightening webinar on Trained Immunity using Nanotherapeutics with Dr. Roy van der Meel and David Schrijver.
🗓️ Date: 23 October 2023
🕒 Time: 4:00 CEST
🔗 Register here: lnkd.in/eKy7bd5Y
#SFNanoJR_1st_webinar @SFNano_official

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