Cole Beeler

Effectiveness and safety of antibiotics in kidney transplant recipients with asymptomatic bacteriuria: a systematic review and meta-analysis of randomised controlled trials ✅ Just Accepted 🔗 bit.ly/4lSOvYd

Switching to oral therapy has become an option for treating infective endocarditis in select patients. In @CIDJournal, authors assess its effectiveness in real-life settings, including patients who would not have been eligible in current guidelines. academic.oup.com/cid/advance-ar…

Doxycycline safety during pregnancy: a large population-based cohort of pregnancies doi.org/10.1007/s15010…

🆕🔥Systematic review & meta-analysis of RCTs @OFIDJournal 4 RCTs (N:478) Effectiveness & safety of antibiotics in kidney transplant recipients with asymptomatic bacteriuria #idxposts academic.oup.com/ofid/article/d…

Continuation versus temporary interruption of immunomodulatory agents during infections in patients with inflammatory rheumatic diseases: a randomized controlled trial ✅ Just Accepted 🔗 bit.ly/4oBjtGC

The anal cancer screening guidelines for PWH recommend testing every 1-2 yrs. But the evidence base is thin, the tests are meh, and resources are limited. Here's why guidelines may be racing ahead of the data (and certainly the resources). @Amit_Achhra blogs.jwatch.org/hiv-id-observa…

Shorter durations of #antibiotic prophylaxis, including no prophylaxis, appear noninferior to longer durations for preventing mortality in patients with #cirrhosis and upper gastrointestinal bleeding. ja.ma/4lYhU3W @bradspellberg @DrToddLee

Finally published 🆕🔥DOTS RCT Among participants with complicated S aureus bacteremia who achieved blood culture clearance, dalbavancin was not superior to standard therapy for achieving a more desirable outcome at day 70 @DrToddLee @BradSpellberg jamanetwork.com/journals/jama/…

Long-term immunogenicity and boostability of the 13-valent pneumococcal conjugate vaccine followed by the 23-valent pneumococcal polysaccharide vaccine in adults receiving immunosuppressive therapy and adults living with HIV ✅ Just Accepted 🔗 bit.ly/40XWJGW

NO ASSOCIATION BETWEEN PREPROCEDURAL FASTING AND WITNESSED PULMONARY ASPIRATION A SYSTEMATIC REVIEW AND META-ANALYSIS I want to bring to everyone's attention the publication of an article we have been working on for some time. Ever been annoyed by having cases cancelled because a patient ate recently? I had this happen a couple of years ago. This motivated me to look at the preoperative fasting literature. I was surprised to learn how little actual evidence there is to support fasting policies. In our recent publication we point out that 1) aspiration rates are no different now than they were before fasting was imposed before administering anesthesia 2) The studies used in fasting research use surrogate outcomes that have never been shown to be relevant to human aspiration events. See the article published in Surgery (@SurgJournal) here: sciencedirect.com/science/articl… There is a pressing need to rethink preoperative fasting policies. New studies are needed that employ proper endpoints to provide guidance for how long patients really need to fast. My guess is, not very long.

Urinary tract infections in immunocompromised patients 🔺Treatment of ASB does NOT reduce symptomatic infections and may LEAD to resistance and adverse events. journals.lww.com/co-infectiousd…

🆕💫Nationwide retrospective cohort study Among the 471 694 eligible patients, 63.3% received 2 g/day and 36.7% received 1 g/day of ceftriaxone. Outcomes of ceftriaxone 2 g versus 1 g daily in hospitalized patients with pneumonia #idxposts academic.oup.com/jac/advance-ar…

🆕💫 Viewpoint @JAMAInternalMed Nitrites for Urinary Tract Infection—Time to Say Goodbye? Cc @BradSpellberg #idxposts jamanetwork.com/journals/jamai…

Patterns of decline in measles, mumps, and rubella neutralizing antibodies and protection levels through 10 years after a second and third dose of MMR vaccine ✅ Just Accepted 🔗 bit.ly/4jqugQy

Incidence of Breakthrough Fungal Infections in Patients with Isavuconazole Prophylaxis: A Systematic Review and Meta-Analysis ✅ Just Accepted 🔗 bit.ly/41Yjyd5

🆕💫MidLine_PICC RCT Midline Venous Catheter vs Peripherally Inserted Central Catheter for Intravenous Therapy #idxposts jamanetwork.com/journals/jaman…

Potential Impact of Doxycycline Post-Exposure Prophylaxis on Tetracycline Resistance in Neisseria gonorrhoeae and Colonization with Tetracycline-Resistant Staphylococcus aureus and Group A Streptococcus ✅ Just Accepted bit.ly/43iUM9W

An observational cohort study of bronchoalveolar lavage fluid galactomannan and Aspergillus culture positivity in patients requiring mechanical ventilation ✅ Just Accepted ✍️ @CatGaoHow, @NM_lung 🔗 bit.ly/3XbAonp

UTI vs "UTI" ⁉️ In this cohort of patients diagnosed with "UTI" only about 30% had symptoms consistent with infection. ED setting and patients with mental status changes are key opportunities for antibiotic stewardship. onlinelibrary.wiley.com/doi/10.1002/na…

Prophylaxis for Spontaneous Bacterial Peritonitis: Thing we do for no reason? @DrToddLee @BradSpellberg @ABsteward @ebtapper academic.oup.com/cid/advance-ar…