Patrick Bos

943 posts

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Patrick Bos

Patrick Bos

@egpbos

eScientist @eScienceCenter / freelance (data) scientist & RSE / cosmologist / HPC, data science, C++ & Python / my tweets represent your opinion

Nederland Katılım Eylül 2008
604 Takip Edilen204 Takipçiler
Patrick Bos
Patrick Bos@egpbos·
What do you feel when scrolling Twitter?
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Ivo van Vulpen
Ivo van Vulpen@IvovanVulpen·
In navolging van de @PartijvdDieren heb ik net weer een evaluatie van een @NWONieuws commissie afgesloten met de opmerking: "Voorts ben ik van mening dat er een einde moet komen aan het scoren op een schaal van 9-1 bij onderzoeksvoorstellen". #langeadem #van1tot10
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Vincent D. Warmerdam
Vincent D. Warmerdam@fishnets88·
Nothing extremely major, but I've ported my blog over to Mkdocs-Material (with Insiders)! Findable at koaning.io Did a bunch of small hacks to get it to how I wanted it but it was a pleasant experience to port.
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Patrick Bos
Patrick Bos@egpbos·
Ok, one more thing while I'm threadin' (even though nobody's readin'): "left wing" people leaving now because of the evil rich man are just as sad as the "right wing" people leaving to Parler or Truth Social because of the evil globalist elite (or whatever?). Grow up! Ok, bye!
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Patrick Bos
Patrick Bos@egpbos·
Ok, back to doomscrolling twitter dot com!
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Patrick Bos
Patrick Bos@egpbos·
Why is everybody so obsessed with this one platform and its owner? You all do know that it's still possible to host your own website, right? Web 1.0 never went away. Seems we just got addicted to 2.0's FOMO platforms and kinda forgot what the web was about in the first place.
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Aleksandar Shulevski
Aleksandar Shulevski@shulevski·
Stop this madness. We should all shout from the rooftops, this is way more important than any EDI initiative. "While Omicron causes mild, non-fatal infection, the Omicron S-carrying virus inflicts severe disease with a mortality rate of 80%."biorxiv.org/content/10.110…
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Patrick Bos
Patrick Bos@egpbos·
@shulevski It's the reference on biorxiv you mentioned. "WT and Omi-S caused mortality rates of 100% (6/6) and 80% (8/10), respectively".
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Aleksandar Shulevski
Aleksandar Shulevski@shulevski·
@egpbos I would like to read that publication about the base strain. Do you have a reference to it?
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Patrick Bos
Patrick Bos@egpbos·
@shulevski It has, under the same experimental conditions as those that produced the 80% number. Spraying a huge dose of the virus straight up the poor mice' noses. Result with base strain: 100% dead. Result with chimera: 80% dead.
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Patrick Bos
Patrick Bos@egpbos·
@shulevski ...which is lower than the 100% mortality of the original. Sure, it's still dangerous, but this stuff is out there in the world already, actually killing people. I think we should try to understand it as well as we can so we can fight it better.
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Aleksandar Shulevski
Aleksandar Shulevski@shulevski·
@egpbos The type where you splice a virus variant which has just caused a pandemic with its original strain to produce a chimera with 80% mortality (in human-analog mice). 😉
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Ben Coates
Ben Coates@bencoates1·
🤷‍♂️
Ben Coates tweet media
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Patrick Bos
Patrick Bos@egpbos·
@shulevski What type? Any splicing? That would cripple virology...
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Aleksandar Shulevski
Aleksandar Shulevski@shulevski·
@egpbos That is interesting, but what is irresponsible and dangerous is the splicing of Omicron and the original strain in a lab with minimum public input on whether these types of research should continue.
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Patrick Bos
Patrick Bos@egpbos·
@shulevski Really interesting actually! 1. Wuhan + Omicron Spike = 80% mortality 2. Wuhan = 100% mortality 3. Omicron = 0% mortality => Omicron, even without spike, is weaker than Wuhan That's in line with the expectation that the virus will evolve towards a common cold / flu.
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