Ethan Yang, MD, PhD

NOHARM study shows up to 22% severe harmful errors, mostly from omissions not bad facts. Traditional benchmarks (like board-exam scores) don’t predict safety. We need harm-focused evaluation & safer AI design.

Scribes can ease burnout, but don’t add much capacity (yet). Best-case cut documentation ~22 min/day; typical results: <1 min/visit. Real productivity comes when they handle the stuff after the visit: orders, prior auth, billing.

New paper in JAMA Neurology: contrast-enhanced vessel wall MRI can help identify unruptured brain aneurysms that are more likely to change or rupture, which may guide who needs closer follow-up or treatment.

PCPs are deeply valuable, and great ones are scarce because we do not reward what they uniquely do. AI will sharpen their insight, help them see more of their patients more often, and strengthen continuity rather than erode it.

CRISPR, in plain English: molecular “scissors” that can edit DNA in your cells. Early trials in adults switch off liver genes to lower bad lipids or harmful proteins.

TODAY, HHS: FDA to remove broad HRT boxed warnings (cardio, breast cancer, dementia), retaining endometrial CA caveat, aligning labels with current evidence. OpenMedicine (openmedicine.io) helps women access safe, personalized care. hhs.gov/press-room/hhs… #HRT

In a 200-person randomized AFib trial (post-cardioversion), those assigned ~1 cup of coffee/day had 39% fewer recurrences over 6 months vs avoiding caffeine. So, coffee isn’t a trigger for everyone. #AHA25

@vercel_dev openmedicine.io

What are you shipping this week?

Launching OpenMedicine.io AI MD + async women’s health care with physicians in the loop. Care for contraception, UTI, BV, PCOS.

@nervemed A

What is the most likely diagnosis❓ A. Fibromuscular Dysplasia B. Renal Artery Stenosis C. Takayasu Arteritis D. Polyarteritis Nodosa

LLM achieves superhuman dx/reasoning on vignettes + ER second-opinion, beating physician baselines and prior AIs. Next: does it translate across tasks?

Practicing a trap door incision for perivisceral endarterectomy at Open Aortic Course. @DeBakeyCVedu

The NIH plans to defund the WHI, the largest clinical trial ever for women that was meant to catch up on missed research. This study has been a fountain of knowledge. The hatred of women from this administration is really from cradle to grave. science.org/content/articl…

@asmah2107 We’re addressing women’s health now with OpenMedicine’s AI doctor. Surgeon-led, evidence-based, built with @_conyay_east to close the care gap. #WomensHealth #AI openmedicine.io

Twitter is cool. But it’s 10x better when you connect with people who like building and scaling GenAI systems. If you’re into LLMs, GenAI, Distributed Systems or backend. say hi.

@buildinpublic From cramps to PCOS to postpartum, OpenMedicine is on it. Our surgeon-designed AI doctor is tackling women’s health now, with my cofounder @_conyay_east. #FemTech #AIDoctor openmedicine.io

What are you working on this week?

@upen946 As a surgeon, I saw the gaps daily. That is why we built OpenMedicine’s AI doctor for women’s health, practical, precise, all the time. @_conyay_east openmedicine.io

👋👋 Monday again!! Time to promote your product. 🚀 Share your product URL.

@csaba_kissi AI doctor focused on women's health today! openmedicine.io

💥 Pitch your startup/side project guys: - Max 7 words - Add your link

@cliftonsellers Women's health deserves better #AIMD openmedicine.io

You got 5 words Sell me your service

Human-in-the-loop (AI+editor) and pro translations beat GPT-4o alone. Quality holds with speed (discharge instructions, portal messages). Caveat: when edits are heavy (e.g., Armenian), efficiency drops and HITL stays essential for now. nature.com/articles/s4174…