إيــاس
1.4K posts

إيــاس
@ey_as_
على عكّاز الأمل، ثابتٌ في المركز، مترنحٌ على الحواف..

Never even liked tennis anyway.


Coffee's effect on your LDL depends on the filter, not the bean. Diterpenes (cafestol, kahweol) ride along in coffee oil. Once absorbed, cafestol activates FXR in the liver, which suppresses CYP7A1, the enzyme that clears cholesterol into bile acids. Less clearance means higher LDL. Paper filters trap the diterpenes. Metal mesh (French press, espresso, moka) does not. Cai 2012 pooled 12 RCTs and found coffee raised LDL by 5.4 mg/dL on average, with the largest effects in unfiltered trials. In 508,747 Norwegians followed for 20 years, filtered coffee drinkers had 15% lower all-cause mortality than non-drinkers. Unfiltered drinkers showed weaker, inconsistent benefit. The same bean produces wildly different cardiovascular exposure depending on what's between the grounds and your cup. Cai, Eur J Clin Nutr 2012: pubmed.ncbi.nlm.nih.gov/22713771/ Tverdal, Eur J Prev Cardiol 2020: pubmed.ncbi.nlm.nih.gov/32320635/







