Florence McCarthy

Our recent work on leukaemia @UCC @ProfTomCotter m.rte.ie/news/2015/1117…

Well done Ryan and all the team. Great to see this in #JMedChem. Thanks to ⁦@IrishResearch for funding.⁦ @ACSBioMed ⁦@UCCResearch⁩ ⁦@uccchemistry @ABCRFCork Discovery of Potent Isoquinolinequinone N-Oxides to Overcome Cancer Multidrug Resistance pubs.acs.org/doi/10.1021/ac…

Save the date! #GP2A2024 will be hosted by @UnivdeCoimbra from the 28th-30th August 2024. Take a look at our keynote speakers. Registration will open shortly with opportunities for oral and poster presentations from early career researchers. More info? gp2a.org/index.php/gp2a…

Congratulations to @kkariko on receiving the Nobel Prize in Medicine or Physiology 👏 Katalin received an honorary doctorate from @UCC in April of this year, for her contribution to the development of mRNA vaccines against COVID-19.

Last but not least, our final early career researcher of today, 3rd year PhD student Vincent Montero @univamu showing good action on spheroids with his quinoxaline topoisomerase inhibitors #GP2A2023

Wonderful first talk from Maria Santos @SantosMMM_MChem @iMedULisboa on spirooxindoles as MDM2 and MDMX inhibitors and tryptophanol derived isoindolinones as p53 reactivators #GP2A2023

Marc-Antoine Bazin @MABazinMedChem @NantesUniv introducing his work on 1,6-naphtyridin-2(1H)-ones as C-terminal inhibitors of Hsp90 #GP2A2023

Next up we have José Marco-Contelles @IQOG_CSIC describing the development of the the multi-target-directed ligand Contilisant for the treatment of Alzheimer's disease through the inhibition of AChE, MAO-B and modulation of H3 and sigma-1 receptors #GP2A2023

Gianluca Sbardella @g_sbardella @UniSalerno driving us down the long and winding road of arginine methyltransferase inhibitors to the first selective PRMT9 inhibitor and the first dual inhibitor of PRMT7 and PRMT9. Good decision to ditch the jacket in hot Marseille #GP2A2023

Another early career researcher presentation from @Helmholtz_HIPS. Marila Nesterkina discussing the use of terpenoid doped cholesteryl esters for effective skin delivery of hydrophobic compounds #GP2A2023

Our next Early Career researcher is 2nd year PhD student Nathan Broudic, from the Cobra lab @insarouen @univrouen describing the impact of geometry on determining biological activity with changes giving rise to DYRK 1A inhibition or cytotoxicity #GP2A2023

Lovely presentation from José I. Borrell, @IQSbarcelona to take us into lunch. Highlighting the importance of serendipity in med chem developing a new photodehydrogenation reaction in the quest for pyrido{2,3-d]pyrimidine-7(8H)-ones as tyrosine kinas inhibitors #GP2A2023

Off to a fabulous start on Day 2 with Philippe Loiseau @BioCIS describing two approaches to the treatment of leishmaniasis, both enzyme inhibition and host-cell vesicular targeting #GP2A2023

Thank you to our Gold sponsor @CEMcorporation for supporting #GP2A2023

And we are off for #GP2A2023 with opening speeches from our chairman @MarchandIICiMed and Dr Biancarelli-Lopes, deputy mayor of Marseille

Next up is our first early career speaker Danica Walsh @Helmholtz_HIPS presenting on IspE inhibitors as unseful anti-infectives in E. coli and K. pneumoniae. #GP2A2023

Great second keynote from @DocKlahn @goteborgsuni featuring inspiring work on siderophore based pro-drugs for antibacterial delivery and artificial glucosinolates for the design of covalent enzyme inhibitors #GP2A2023

A new approach for the treatment of Alzheimer's disease? Valentin Travers--Lesage @CermnUnicaen our second early career speaker introducing his PhD work on self-immolative pleiotropic pro-drugs targeting cholinesterases #GP2A2023

Congratulations to all our graduates on their postgraduate conferring last week, and our best wishes to them in their future careers. Full story - ucc.ie/en/chemistry/n… @SEFSUCC @UCC #chemed @uccconferrings @anita_maguire

Huge Congratulations to all our @uccchemistry PhD students who are graduating today @SEFSUCC @UCC @uccconferrings #phd #conferrings #procession #graduation #graduationprocession #gowns #mace #cork #ireland #fabulous #hugecongrats #veryproud

We are recruiting for three academic positions via the UCC Futures initiative ….. more details via our LinkedIn post at the link below ! linkedin.com/posts/departme…