Francesco Carelli

Modern GWAS can identify 1000s of significant hits but it can be hard to turn this into biological insight. I'm excited to share our new work combining genetic associations and Perturb-seq to build interpretable causal graphs, out today in @Nature:

'like we see in Gaza' spaventoso.

Tutte le altre persone, dopo un anno wittgenstein.it/2024/10/08/tut…

Hold on to your hats! The winners of the 2024 #NikonSmallWorldInMotion competition have finally been revealed, and they're sure to blow you away. View the full video gallery here: bit.ly/47t3L8A

Position-dependent function of human sequence-specific transcription factors | Nature nature.com/articles/s4158…

🚀New update to #AlphaFold Database: Foldseek now integrated! Peer deeper into evolution with new structure-based search feature to find similar proteins with remote homology. The search includes experimentally-determined protein structures from @PDBe. ebi.ac.uk/about/news/upd…

La scomparsa degli avvoltoi in India ha causato la morte di centinaia di migliaia di persone ilpost.it/2024/08/02/avv…

Il punto di non ritorno ilpost.it/2024/07/06/dca…

i was skeptical from day one of biden getting on stage with trump hate to say i told you so @gzeromedia

Distruggere le piante di riso modificato geneticamente, frutto del lavoro e dell’ingegno dei ricercatori, è come bruciare i libri in piazza. Anche se non ha la stessa potenza simbolica, ha lo stesso significato. Solo che a farlo non sono dei neonazisti ma degli ecoterroristi.

🪱"All genes are created equal, but some are more equal than others" Happy to share our recent work dissecting a parent-of-origin effect in worms, which could have important implications for our understanding of the evolution of imprinting @IMBA_Vienna doi.org/10.1038/s41586…

1/13 🚨🚨 I am so excited to present our new paper, six years in the making. Here, we provide the first strong evidence that there is a molecular mechanism behind the origins of living fossil lineages! #biology #science #paleontology academic.oup.com/evolut/advance…

Proudly presenting our new findings on how #RNA binding proteins (RBPs) may increase the tolerance of genomes to transposable element (TE) insertions. If you want to know more read this thread or our story @Nature nature.com/articles/s4158…

When the installation guide starts with "devtools::install_github()" and not "install.packages()" or "BiocManager::install()"

1/13 I’m thrilled to announce our comparison of the C. elegans and C. briggsae embryonic lineages by scRNA-seq, led by a talented postdoc, Chris Large, with @RupaKhanal11, Bob Waterston, @JunhyongKim and LaDeana Hillier

Never, stop, fighting! My first Grand Slam title, lost for words, forza!!!!!! 🏆🏆🏆🏆

Last January, I noticed something peculiar in my 2yo’s bedroom that - after a year of obsessive reporting - led me to a profound cosmic revelation about what’s even possible in our universe. A 🧵.

New publication: The histone chaperone SPT2 regulates chromatin structure and function in Metazoa ppu.mrc.ac.uk/news/histone-c… @NatureSMB @GiuliaSaredi #DNADamage #DNARepair

NEW: we don’t reflect enough on how severe the housing crisis is, and how it has completely broken the promise society made to young adults. The situation is especially severe in the UK, where the last time house prices were this unaffordable was in ... 1876.

Fabulous. Policy that makes it less attractive for foreign students to come - foreign student who are a financial net positive to universities.