Dan da dan

@neolithicrumba2 When I started, the first three months were perfect but on December I changed my routine (because i was on vacation) and I forgot 1 💊, I was very scared and feeling guilty, after that the checkup came without reaching undetectable. I became more distressed. THANK YOU SO MUCH 💓

Let’s talk about the science behind late or missed doses. A 🧵 First, let’s understand where the data comes from. When a new drug is developed, it is testing in a lab, putting the new molecule in a dish with HIV. If successful, it’s tested in animals, and then a small group of people (around a dozen in a phase I study) not to find out if it works, but to find out if the drug is safe and how long it stays in the bloodstream. These volunteers are kept in a hospital-like setting and their blood is taken every few hours. This determines the drug’s half life, or how long half the dose remains in their body. For a drug like dolutegravir (the D in TLD), the half life is around 14 hours. That tells the researchers that it can be dosed one time a day. More specifically, they’re looking for IC90, which is the time 90% is still suppressed. With dolutegravir, that’s 30 hours, so a full effective dose is still in the bloodstream for more than one day. Next up: phase II tesing

Las almas...

El herpes zóster aparece antes y con más frecuencia en personas con el VIH. 👉 Se puede prevenir, pero la vacunación sigue siendo baja. 📲 Lee «La Noticia del Día» de gTt-VIH 🧡 🔗 gtt-vih.org/publicaciones/…

@galo_bertin Yo. Me entristece pero es una realidad.

Cuantos de ustedes creen que estarán solos en la vejez???

La incertidumbre. ✍️.

✨️♥️✨️

El cáncer bucofaríngeo también es un tema clave en personas con VIH.El VPH, el tabaquismo y otros factores aumentan el riesgo.👉 Lesiones en boca o garganta 👉 Dolor persistente 👉 Dificultad al tragarNo lo ignores. La detección oportuna puede salvar vidas.#VIH #VPH #AtencionIntegral #PrevenciónCombinada #InformateYAprende

Ojo con los riñones si vives con #VIH. Algunos medicamentos y otras condiciones pueden afectar su función. Chequeos regulares = detectar a tiempo y cuidar lo que nos cuida #AtenciónIntegralVIH #informateYAprende

¿Eres estudiante de nivel superior en una escuela pública y vives con VIH? 👉Puedes participar en movilidad internacional o viajar por estudios 👉Y llevar contigo tu tratamiento sin interrupciones Vivir con VIH no es un impedimento para crecer y cumplir tus metas. 🤝 En @DVVIMSS y la Clínica del Viajero UNAM @capvunam te apoyamos en la gestión con las instituciones de seguridad social. #VIH #DerechoALaSalud #EducaciónSinBarreras #PrevenciónCombinada

@bydavidoficial Si ya habíamos roto, qué te hizo pensar que aquí seguíamos

15 de abril, diarios.

When we get a t-cell panel, the results come from a flow-cytometry machine that counts both CD4 and CD8 cells. The results are both quantified (given a number) and listed as a %. CD4s are T-helper cells. Their job is to identify cells in our body that are infected by a virus. They do this by finding changes in the cell’s coating. They then make a “key” that fits into the changed part of the cell’s membrane, and it churns out these keys, which are called antibodies. They get picked up by CD8 cells that then use the key to find and attach to infected cells and then kill them. That’s how our bodies clear viral infections. These primed CD8 cells can alert other parts of our immune system to get into action. The signals it sends out are inflammatory, which is fine in the short term. Remember, when we get sick, the fever, rash, stomach upset, swelling, etc., are actually caused by our immune system’s reaction to infection, not the disease itself. The problem comes from ongoing low-grade inflammation. A good example is arthritis. It creates mild inflammation in the joints, and over time, those joints deteriorate and the person loses function in their fingers, knees, and other joints. The elevated CD8s in a PLWH is similar, bringing on old-age diseases sooner, due to the low grade inflammation. As far as the numbers go, each T-cell test may have a different reference range. The result will say something like 450 to 1500 is normal. On the post I commented on, the normal range was 462-1306. For the percentage, normal is around 25 to 50, depending on the flow cytometry maching and how it’s calibrated. On the test pictured, it was 29-54%. These “normal” values are for an HIV-negative person. It’s worth noting that when the values are high, it can be an indicator of other conditions, like lupus. More isn’t always better. By way of reference, <200 CD4 is an indicator of AIDS and that means the person can be vulnerable to opportunistic infections. The equivalent in percentages is <12%. It’s important to remember that CD4 counts are highly variable. They normally change from morning to night. They can change if you have a simple infection, you don’t sleep well, or if you’re stressed out. That’s why it’s best not to give too much weight to a single result. Doctors look at trends over time, like 4-5 tests in a row. It should trend higher over time, despite an occaisional dip, which is a normal part of life. Another way to see past individual fluctuations is to look at the percentages, which are more stable over time. Unfortunately, we’ve been taught (along with our doctors) to focus on CD4 counts, which can sometimes be misleading. After living with HIV for more than three decades, I feel the whole CD4 roller coaster is bullsh*t. You go in, your doc says, “Yay! You have fifty more CD4s! That’s great! Congratulations!” Then the next time, if it goes down, he says, “Hey, your CD4 went down by fifty, but don’t worry about it.” It’s an emotional game, but the real questions is, “Are the results actionable?” That means, does the doctor need to do something? Change meds? Add a pill? Order more tests? In thirty years, that’s never happened. The real indicator for a doctor needing to take action would be a high viral load, but in many countries, a VL test only happens once a year, while a CD4 happens more often (because the test is cheaper). From my experience, we all have a different path. We also don’t know what our “normal” was. CD4 tests aren’t given to negative people, so one person’s normal may be in the 500s and another will be over 1,000. The one with a lower normal won’t get sick more than the other. There are too many immune factors at work to see immune function in a single number. Some PLWH will slowly, over years, see their CD4 return to higher numbers, others will rise more quickly. From a clinical perspective, one is not better than the other. The important thing is that we’re all moving in the right direction ❤️

@DVVIMSS @capitanlongares @m_angel_ascenci @dredgarbarragan @RedDiversidad @Prosavih @DiversexVC @AlanMike @gTtVIH @CarlosLopezLina @mgmurcia Lo platiqué en cita algo que me está sucediendo y creo que lo minimizó, no le dio importancia.

Las afecciones dermatológicas pueden ser una señal importante en personas con VIH. Erupciones, infecciones en la piel, dermatitis o lesiones persistentes 👉 pueden indicar alteraciones inmunológicas o efectos del tratamiento. No lo ignores. La piel también habla de tu salud. #VIH #InformateYAprende #Dermatología

@DVVIMSS @DiversexVC @RedDiversidad @gTtVIH @soylajefita @salmazan71 @maurodriguez @Jicamario @mgmurcia @sidvimx @dredgarbarragan En qué porcentaje de presentan dichas situaciones?

Las personas con #VIH en tratamiento ARV vivimos más… pero también enfrentamos comorbilidades como diabetes, hipertensión, daño renal y cardiovascular. 👉 Diagnóstico oportuno 👉 Atención integral 👉 Control adecuado No es solo sobrevivir, es vivir con calidad. #AtenciónIntegral #InformateYActua

@gTtVIH Hola. El link dice que no se encuentra la página.

La calidad de vida en el VIH ya no depende solo del control del virus. Un estudio en «BMC Public Health» sitúa la #SaludMental como factor central del bienestar. 📲 Lee «La Noticia del Día» de gTt-VIH 🧡 🔗 gtt-vih.org/publicaciones/…

Solo el 20.1% de la población adulta en Mx se ha hecho una prueba de VIH alguna vez en la vida, de acuerdo con la #ENSANUT Continua. Con un porcentaje tan bajo, no es posible detectar a tiempo y vincular a tratamiento ARV💊 Tablas en Salud Pública de Mx: saludpublica.mx/index.php/spm/…

En VIH no todo es CD4 y carga viral. Las personas en tratamiento también deben vigilar: ➡️Función renal ➡️Riesgo cardiovascular ➡️Glucosa y lípidos ➡️Salud ósea ➡️Coinfecciones 👉 La atención integral salva vidas. 👉 Detectar a tiempo evita complicaciones. No es solo controlar el virus, es cuidar toda la salud. #VIH #AtencionIntegral #PrevenciónCombinada #InformateYActua