Bagvestor
491 posts





$RVMD massive 150/180 bull debt for 6/2026 about $3.6 million for an upside bet $XBI $IBB

Revolution Medicine’s ($RVMD) Daraxonrasib Just Did Something Few Thought Possible in Pancreatic Cancer For decades, pancreatic cancer has been one of the most frustrating diseases in medicine. We’ve watched immunotherapy transform entire fields and targeted therapies change the trajectory of lung cancer and hematologic malignancies. Pancreatic cancer has largely been left behind. That’s why this study led to a standing ovation at ASCO. The Phase 3 data for daraxonrasib showed median overall survival of 13.2 months versus 6.7 months with chemotherapy. 13.2 months versus 6.7 months!! This is one of the most important advances pancreatic cancer has seen in years, and with the FDA’s new access program, it will be in hands of physicians this week. What’s even more interesting is what this says about the future of cancer treatment itself. For most of modern oncology, we’ve classified cancer based on geography: lung, breast, colon, pancreas. But biology doesn’t really care where a tumor started. What matters is what’s driving it. In this case, researchers went after one of the most important pathways in cancer biology, KRAS, a target that many considered effectively undruggable not that long ago. So… the lesson here extends beyond pancreatic cancer into precision medicine. A win for the idea that if we can understand the molecular machinery driving disease, we can build therapies that are dramatically more effective than broadly toxic treatments. A standing ovation at ASCO is rare, but for pancreatic cancer, it feels earned.










