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Bagvestor

@hawkking1515

One of the biotech noob

Katılım Kasım 2022
279 Takip Edilen135 Takipçiler
민몽몽
민몽몽@MongMongMin33·
6모 나보다 잘 본 애가 자기 실력 처참해서 휴학하고 내후년 변시 노려야될 것 같다 이지랄 하는데 “그래. 제발 휴학해라.”라는 말이 목구멍까지 올라왔다가...(생략)
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Bagvestor
Bagvestor@hawkking1515·
Add more $cccc $ctmx
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Bagvestor
Bagvestor@hawkking1515·
@hari_raang 진심 방금까지 자퇴할까 고민함요 ㅋㅋ;; 그나마 자신있던게 민사례인데 세상무너진느낌 ㅜ
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@hari_raang·
@hawkking1515 저는 사기 아예 감이 안와요ㅋㅋ큐ㅠㅠㅠㅠㅠㅠ 근데 당장 눈에 보이는 게 객이라... 방학 때 최판도 해야하는데 할 게 너무 많네요ㅠㅠ
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@hari_raang·
6모 객 채점했는데 너무 우울하고 5모보다 더 떨어질 것도 없는 점수였는데 떨어졌고 뭘 어떻게 해야할지 모르겟다 이대로 휴학해야 하나..? 아님 수료하고 17회를 노려...? 이 점수로 올해 시험을 볼 수 있는 건 맞아..? 나 진짜 미치겠다
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Bagvestor
Bagvestor@hawkking1515·
6모가 끝나고 집에 가서 누워있다가 민사례 2문을 처음부터 끝까지 다 조져진 것을 깨닫고 다시 학교에 나와 일단 앉아있는중.. 나의 리걸마인드는 존재하긴 하는걸까?😭
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canoebrookbl
canoebrookbl@canoebrookbl·
$prax no position but this one has the potential to be in half in 6 m.
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Specialsituationz
Specialsituationz@hannibalspeaks·
Hannibal’s law #44: A drug powerful enough to abate colitis is going to have some consequential side effects eventually. You can’t hit immune system that hard and have no undesirable effect.
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Han Seoul Ohno
Han Seoul Ohno@han_seoul_ohno·
$CELC -25% PM Phase 3 VIKTORIA-1 Results 11 m PFS reported : goal was 13 mo PFS Not involved but this is a bad 24 hours for BioX
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Marc de Garidel
Marc de Garidel@RGaridel18419·
$ABVX Congratulations to Abivax! All of our shareholders are becoming future patients. It’s called stress induced IBS. We are winning like never before! Thank you for your attention to this matter. - MDG
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Dr Danish
Dr Danish@operationdanish·
Why I’m bullish on $RVMD and RAS(ON) inhibitors. Most people looked at Revolution Medicine’s daraxonrasib data this weekend and saw a pancreatic cancer breakthrough. And to be fair, it is. Doubling median overall survival in metastatic pancreatic cancer is the kind of result that earns a standing ovation at ASCO. But I think the bigger story is what the data may say about Revolution Medicine itself. For decades, RAS has been one of the most important targets in cancer biology. Mutations in the RAS pathway are found in roughly 25-30% of all human cancers, including pancreatic, lung, colorectal, ovarian, and many blood cancers. The problem was that RAS was considered undruggable. Scientists knew it was driving cancer. They just couldn’t figure out how to shut it off. That’s the opportunity Revolution Medicine was built around. Rather than developing a single drug for a single cancer, the company built a technology platform designed to target RAS proteins in their active, cancer-driving state. Their approach uses what they call RAS(ON) inhibitors, a new class of medicines designed to directly engage activated RAS signaling. Daraxonrasib is one product of that platform. The important question isn’t whether daraxonrasib can become a successful pancreatic cancer drug. The important question is whether these results represent the first large-scale validation of Revolution’s broader approach to targeting RAS-driven cancers. Because if the underlying technology works, the opportunity extends far beyond pancreatic cancer. It potentially extends into lung cancer, colorectal cancer, and a range of other tumors where RAS mutations act as a core disease driver. The best biotechnology companies don’t create a single blockbuster. They create a repeatable engine for discovering them. Genentech did it with antibodies. Vertex did it with CFTR biology. Moderna did it with mRNA. What investors are trying to determine now is whether Revolution Medicine has built a similar engine for one of the most important pathways in oncology. It’s still early. Resistance mechanisms will emerge. Additional trials will need to confirm the breadth of the approach. But this weekend may ultimately be remembered as something bigger than a pancreatic cancer breakthrough. It may be remembered as the moment the oncology community started believing that RAS, one of cancer’s most important biological engines, could finally be systematically targeted.
Dr Danish@operationdanish

Revolution Medicine’s ($RVMD) Daraxonrasib Just Did Something Few Thought Possible in Pancreatic Cancer For decades, pancreatic cancer has been one of the most frustrating diseases in medicine. We’ve watched immunotherapy transform entire fields and targeted therapies change the trajectory of lung cancer and hematologic malignancies. Pancreatic cancer has largely been left behind. That’s why this study led to a standing ovation at ASCO. The Phase 3 data for daraxonrasib showed median overall survival of 13.2 months versus 6.7 months with chemotherapy. 13.2 months versus 6.7 months!! This is one of the most important advances pancreatic cancer has seen in years, and with the FDA’s new access program, it will be in hands of physicians this week. What’s even more interesting is what this says about the future of cancer treatment itself. For most of modern oncology, we’ve classified cancer based on geography: lung, breast, colon, pancreas. But biology doesn’t really care where a tumor started. What matters is what’s driving it. In this case, researchers went after one of the most important pathways in cancer biology, KRAS, a target that many considered effectively undruggable not that long ago. So… the lesson here extends beyond pancreatic cancer into precision medicine. A win for the idea that if we can understand the molecular machinery driving disease, we can build therapies that are dramatically more effective than broadly toxic treatments. A standing ovation at ASCO is rare, but for pancreatic cancer, it feels earned.

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Persimmon Tree Investments
Persimmon Tree Investments@PersimmonTI·
$RVMD $ERAS Take note, Erasca — this is how you disclose a Gr5, unfortunate patient death:
Persimmon Tree Investments tweet mediaPersimmon Tree Investments tweet media
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Bagvestor
Bagvestor@hawkking1515·
$ctmx I didn't want to allocate more than 30% of my portfolio to a single bio stock, but I couldn't resist the current price.😅
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Han Seoul Ohno
Han Seoul Ohno@han_seoul_ohno·
$CCCC C4 Therapeutics writeup now live - written with the fantastic @biotechsanya2! Trading at $3.5, a grossly undervalued asset in multiple myeloma. Data from $BMY at ASCO in the coming days is just the first catalyst of many! Full Writeup on Substack: open.substack.com/pub/hanseouloh…
Han Seoul Ohno tweet media
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Specialsituationz
Specialsituationz@hannibalspeaks·
$CNTB is the most asymmetrical set-up I know off. It's a free binary on a blockbuster indication which has a 70% PoS.
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