

Deficiency of IgA antibodies influences how well the immune system can maintain control of intestinal bacteria, finds new study involving pediatric patients with varying IgA levels. @henricksonlab @LabSilverman scim.ag/2LQ
Sarah Henrickson
183 posts

@henricksonlab
defining pediatric immune health and the mechanisms by which chronic inflammation and immune deficiency disrupt it


Deficiency of IgA antibodies influences how well the immune system can maintain control of intestinal bacteria, finds new study involving pediatric patients with varying IgA levels. @henricksonlab @LabSilverman scim.ag/2LQ

Congrats to @ChildrensPhila's Dr. Evan Weber, recipient of the @NIHDirector's New Innovator Award! Dr. Weber will pursue a novel approach to reprogram T cells with enhanced tumor killing function, paving the way for more efficacious #cancer therapeutics. @CHOPCancerCntr

1/ Just in! We report the first humans with inherited pre-TCR⍺ deficiency in @sciencemagazine. Dive into our fascinating findings on complete and partial forms of pre-TCRα deficiencies, including a common variant in the Middle East and South Asia. science.org/doi/10.1126/sc…

Join us in congratulating the 65 new fellows elected to the American Academy of Microbiology! Fellows are elected annually through a selective, peer-review process based on their scientific achievements and original contributions. See the full list: asm.social/1Id




It was a privilege to welcome @henricksonlab to Grand Rounds today to discuss genetic testing and interpreting variants of uncertain significance. Thank you for providing a very engaging and informative talk on a very important topic! @ChildrensPhila @PennMedicine @AAAAI_org











Deficiency of IgA antibodies influences how well the immune system can maintain control of intestinal bacteria, finds new study involving pediatric patients with varying IgA levels. @henricksonlab @LabSilverman scim.ag/2LQ




Studying human pediatric and mouse IgA deficiency, in collaboration with @LabSilverman, shows increasing exposure of commensal microbes to the systemic immune response yields immune dysregulation -- helping understand why only some IgA deficient patients are symptomatic!