Sarah Henrickson

183 posts

Sarah Henrickson banner
Sarah Henrickson

Sarah Henrickson

@henricksonlab

defining pediatric immune health and the mechanisms by which chronic inflammation and immune deficiency disrupt it

Philadelphia, PA Katılım Eylül 2019
711 Takip Edilen816 Takipçiler
Sabitlenmiş Tweet
Sarah Henrickson
Sarah Henrickson@henricksonlab·
Studying human pediatric and mouse IgA deficiency, in collaboration with @LabSilverman, shows increasing exposure of commensal microbes to the systemic immune response yields immune dysregulation -- helping understand why only some IgA deficient patients are symptomatic!
Sarah Henrickson tweet media
Science Immunology@SciImmunology

Deficiency of IgA antibodies influences how well the immune system can maintain control of intestinal bacteria, finds new study involving pediatric patients with varying IgA levels. @henricksonlab @LabSilverman scim.ag/2LQ

English
2
16
82
30.7K
Evan Weber
Evan Weber@EvanWeberPhD·
Many thanks to @NIH_CommonFund @theNCI for this honor and @CHOP_Research @CHOPCancerCntr @PennMedicine for their continued support! We look forward to taking epigenetic reprogramming to the next level to improve CAR T cell fitness and efficacy.
CHOP Research@CHOP_Research

Congrats to @ChildrensPhila's Dr. Evan Weber, recipient of the @NIHDirector's New Innovator Award! Dr. Weber will pursue a novel approach to reprogram T cells with enhanced tumor killing function, paving the way for more efficacious #cancer therapeutics. @CHOPCancerCntr

English
11
0
81
3.8K
Sarah Henrickson
Sarah Henrickson@henricksonlab·
So excited that our paper on preTCRa is out! It was a wonderful experience working with this collaborative, international immunology research team. This story emphasizes how much we can learn from our rare patients—both about new diseases and basic immune mechanisms.
Vivien Béziat@BeziatV

1/ Just in! We report the first humans with inherited pre-TCR⍺ deficiency in @sciencemagazine. Dive into our fascinating findings on complete and partial forms of pre-TCRα deficiencies, including a common variant in the Middle East and South Asia. science.org/doi/10.1126/sc…

English
3
3
33
2.9K
Weitzman Lab
Weitzman Lab@WeitzmanLab·
I am honored to be elected a fellow of the American Academy of Microbiology. Congrats to all other outstanding new fellows elected. Thanks to all who have supported my career & especially all trainees I have been fortunate to work with over the years who have done great science
ASM@ASMicrobiology

Join us in congratulating the 65 new fellows elected to the American Academy of Microbiology! Fellows are elected annually through a selective, peer-review process based on their scientific achievements and original contributions. See the full list: asm.social/1Id

English
31
7
144
17.5K
Sarah Henrickson
Sarah Henrickson@henricksonlab·
@Info4PI Her passion for, and dedication to, the patients, providers and research in our field was inspiring and her kind words have encouraged me and countless others. She will be missed and her work remembered!
English
0
0
2
138
Jeffrey Modell Foundation (JMF)
The Jeffrey Modell Foundation is deeply saddened to announce that our beloved Co-Founder, Vicki Modell, has passed away. Vicki was a strong, courageous, and empathetic leader, and was the heart of the Foundation for 37 years. We mourn her death and will miss her terribly.
Jeffrey Modell Foundation (JMF) tweet media
English
25
18
61
22.1K
Sarah Henrickson retweetledi
Jennifer E Wu
Jennifer E Wu@jenewu1·
In vitro models of CD8 T cell exhaustion make high-throughput interrogation easy, but can they be used to discover real Tex biology with therapeutic relevance? Read to find out! In our new work from the @EJohnWherry lab, out now at @SciImmunology, we... bit.ly/45yOFMB
English
12
42
131
29.4K
Michael J. Hogan
Michael J. Hogan@MikeHoganPhD·
Excited to announce that I will be starting my own lab as an assistant professor on Jan 1st, 2024 at the University of Pennsylvania School of Veterinary Medicine @pennvet, Dept of Pathobiology. Thanks to the many people who helped me get to this point!
Michael J. Hogan tweet media
English
61
29
666
56.1K
Sarah Henrickson retweetledi
Children's Hospital
Children's Hospital@ChildrensPhila·
In a new @SciImmunology study, our researchers have shown that IgA acts as a “tuner” that regulates the number of microbes the body sees every day. This may explain why some patients with IgA deficiency have symptoms, while others do not. Read more below. ms.spr.ly/6013g5vCv
English
2
5
18
2.8K
Sarah Henrickson
Sarah Henrickson@henricksonlab·
@BrodinPetter @LabSilverman Thanks Petter! Starting from the questions posed by human immune dysregulatory conditions leads in interesting directions--and there so much left to do!
English
0
0
3
236
Petter Brodin
Petter Brodin@BrodinPetter·
Finally got time to read this excellent human/mouse immunology paper by @LabSilverman @henricksonlab. Human IgA deficiency is highly variable and often mild which has been curious given that IgA seem so important for microbial colonization, and healthy immune-microbe interactions. Conrey et al show that combined loss of systemic and secretory IgA increases gut bacterial translocation and increased immune activation (IL-12p40, IL-6 etc): science.org/doi/10.1126/sc….
English
2
5
26
4.7K
Sarah Henrickson
Sarah Henrickson@henricksonlab·
Studying human pediatric and mouse IgA deficiency, in collaboration with @LabSilverman, shows increasing exposure of commensal microbes to the systemic immune response yields immune dysregulation -- helping understand why only some IgA deficient patients are symptomatic!
Sarah Henrickson tweet media
Science Immunology@SciImmunology

Deficiency of IgA antibodies influences how well the immune system can maintain control of intestinal bacteria, finds new study involving pediatric patients with varying IgA levels. @henricksonlab @LabSilverman scim.ag/2LQ

English
2
16
82
30.7K
Science Immunology
Science Immunology@SciImmunology·
Deficiency of IgA antibodies influences how well the immune system can maintain control of intestinal bacteria, finds new study involving pediatric patients with varying IgA levels. @henricksonlab @LabSilverman scim.ag/2LQ
Science Immunology tweet media
English
2
37
120
46.4K