Thierry Couffinhal

207 posts

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Thierry Couffinhal

Thierry Couffinhal

@iCouffi

Passionné de médecine et de sciences CardioVasculaires Reflète uniquement mes opinions @UnivBordeaux @InsermU1034 @CHUbordeaux

Pessac (Bordeaux) Katılım Ocak 2018
53 Takip Edilen88 Takipçiler
Thierry Couffinhal retweetledi
Science Magazine
Science Magazine@ScienceMagazine·
An early giraffe ancestor’s unique head and neck fossils suggest an alternative explanation for the evolution of modern giraffes’ long necks: sexual selection. Learn more in a new Science study: fcld.ly/rhhwfwi
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Thierry Couffinhal
Thierry Couffinhal@iCouffi·
SHiVA pour comprendre et prévenir les trouvbles cognitifs en luttant contre la maladie occulte des petis vaisseaux cérébraux
RHU SHiVA@RHU_SHiVA

The #SHiVA research program aims to develop new personalized management of cerebral Small Vessel Disease #cSVD, preventive strategies and accelerate the discovery of novel therapeutic targets. (1/5) ⬇️

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Thierry Couffinhal
Thierry Couffinhal@iCouffi·
Très fier d’avoir particpé à ce travail conduit par le Pr S. Debette dans le cadre du RHU SHiVA, un consortium bordelais pour comprendre la maladie des petits vaisseaux dans les troubles cognitifs.
RHU SHiVA@RHU_SHiVA

Our study providing initial evidences to prioritize #TRIM47 to decipher molecular mechanisms underlying cerebral #smallvesseldisease is out now. #TRIM47 #endothelialpermiability #WMH #lacunes #smallvesseldisease #stroke #dementia academic.oup.com/brain/advance-…

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Thierry Couffinhal retweetledi
Thierry Couffinhal retweetledi
Sébastien Rubin
Sébastien Rubin@SebastienRubin·
Randomisation mendélienne, GWAS, multi-omics … à la Masterclass de la @sfhta aujourd’hui ! On se régale !
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Raj Gupta
Raj Gupta@Dr_RajatGupta·
Great work from @SebastienRubin The CAD GWAS locus at chr6p24 is called the PHACTR1 locus. However my lab and others have shown an effect on Endothelin-1 expression. This paper shows NO vascular phenotype for PHACTR1 KO. My editorial summarizing the data: ahajournals.org/eprint/ZX4ZHPG…
Sébastien Rubin@SebastienRubin

Despite robust associations in GWAS with many vascular diseases, loss of PHACTR-1 function in the cells involved in vascular physiology does not appear to induce a pathological vascular phenotype in mice. Our work 👇👇 @insermU1034 @SBurtey @PLTharaux ahajournals.org/doi/10.1161/AT…

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Thierry Couffinhal retweetledi
Inserm U1034 - Biology of Cardiovascular Diseases
Take a look to @DuplaaC Team latest paper out in Cold Spring Harbor Perspectives in Medicine on the role of Wnt/frizzled Signaling in Blood-Retinal- and Blood-Brain-Barrier Integrity. Thanks P D’Amore for the invitation. doi: 10.1101/cshperspect.a041219. #Wnt #endothelium
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RHU SHiVA
RHU SHiVA@RHU_SHiVA·
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