iMeta

🤔 Curious what #iMeta is and why we reached IF = 33.2 in just 3 years? 🚀 ⚡Wondering how we process manuscripts so fast while driving cutting-edge discoveries? 🎥 Watch this short video — the answers are here. More details about iMeta: onlinelibrary.wiley.com/journal/277059… #Bioinformatics #microbiome #journal #sciencecommunication @wileymicrobio @WileyBiomedical @WileyOnc_Hem @WileyEcolEvol

MetOrigin 2.0: Advancing the discovery of microbial metabolites and their origins - Yu - 2024 - iMeta - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/im…

Patient-derived organoid-immune co-cultures integrated with multi-omics reveal immunotherapy resistance mechanisms in urothelial carcinoma ❄️➡️🔥 Erdafitinib turns FGFR3-mutant “cold” bladder tumors hot again by rewiring the FGFR3–STAT5–IRF2 immune axis. onlinelibrary.wiley.com/doi/10.1002/im…

Integrative host–microbiome modeling uncovers the implication of oral–gut translocation in advanced cirrhosis Cirrhosis drives an “oralization” of the gut microbiome, reshaping microbial metabolism toward ammonia and acetate production. onlinelibrary.wiley.com/doi/10.1002/im…

Spinal cord injury induces acute microbiome shock and system-wide transcriptomic reprogramming 🤔The newly developed SCIGAMA maps gut microbiota and systemic molecular responses after spinal cord injury (SCI). onlinelibrary.wiley.com/doi/10.1002/im…

FluNexus: A versatile web platform for antigenic prediction and visualization of influenza A viruses - Li - 2026 - iMeta - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/im…

Intratumoral Enterobacter hormaechei drives gemcitabine resistance in pancreatic cancer via cddL-mediated drug inactivation 💊 Antibiotic co-treatment restores drug sensitivity while reducing chemotherapy dosage.@WileyHealth #Pancreatic #Microbiome onlinelibrary.wiley.com/doi/10.1002/im…

Navigating the future of nano‐pesticides: A perspective on design, efficacy, mechanisms, and environmental stewardship 🌱Nano-pesticides are reshaping crop protection toward sustainable agriculture. onlinelibrary.wiley.com/doi/10.1002/im…

🔥Latest research! Microbial synthetic community ARC prevents aflatoxin and increases rhizobia-legume nodulation couplingly #MicrobialSolutions #FoodSecurity doi.org/10.1002/imt2.7…

⚡Pyridoxal Reprograms Peroxisomal Hydrogen Peroxide Metabolism to Induce Lethal Oxidative Stress in Ovarian Cancer. Unmodified PL unleashes a H2O2 storm, killing ovarian cancer cells without needing conversion! doi.org/10.1002/imm3.7…

You are what you eat! Unlocking gut microbiota-mediated biotransformation of dietary phytochemicals @WileyHealth doi.org/10.1002/imo2.7…

L-EasyARG: A long-read metagenomics tool for rapid antibiotic-resistance-gene profiling #Metagenome #ARG doi.org/10.1002/imo2.7…

🔥Latest Article! Single-cell analysis uncovers smooth muscle cell subtype switching as a key driver of fibrosis, inflammation, and vascular disruption in aortic dissection.@WileyHealth #AorticDissection #SingleCell #Vascular #Fibrosis onlinelibrary.wiley.com/doi/10.1002/im…

🧬Chromatin unwinding state for in situ identification and lineage tracing of circulating tumor cells ⚙️ This attention-based model traces rare CTCs directly from blood without enrichment, supporting early detection and anti-metastatic strategies. onlinelibrary.wiley.com/doi/10.1002/im…

The DGKα/PA axis drives immune evasion by activating NF-κB and upregulating PD-L1 in tumors. ⚙️ Inhibiting DGKα reduces PD-L1, enhances CTL infiltration, and improves ICI efficacy, with plasma PA as a potential biomarker in gastrointestinal cancers. onlinelibrary.wiley.com/doi/10.1002/im…

💪Chondroitin sulfate restores muscle mass via gut–muscle axis remodeling through sugar–bile acid metabolism reprogramming ⚙️ Enrichment of Lactobacillus johnsonii and secondary bile acids activates PAX7/NMRK2 pathways, promoting muscle regeneration. onlinelibrary.wiley.com/doi/10.1002/im…

🧐Microbial metabolites in tumor epigenetic regulation The gut microbiome reshapes tumor epigenetics via metabolite signaling.Bile acids and tryptophan-derived ligands regulate HDAC/DNMT/AhR pathways, altering chromatin states and tumor behavior. onlinelibrary.wiley.com/doi/10.1002/im…

Spatial multi-omics identifies a NOTCH3-mediated capillary–mCAF crosstalk driving immune exclusion in hepatocellular carcinoma Fibrosis-driven immune exclusion in HCC is linked to endothelial–CAF crosstalk… onlinelibrary.wiley.com/doi/10.1002/im…

👏A large-scale single-cell transcriptomic atlas indicates the immune panorama of influenza A infection We generated a large-scale single-cell transcriptomic atlas from peripheral blood, profiling more than 612,010 cells from 97 individuals. #HostResponse onlinelibrary.wiley.com/doi/10.1002/im…

Two stable gut microbiome guilds predict liver tumor class and treatment responses ⚙️ Functionally opposing microbial guilds highlight an ecological basis for tumor progression and clinical outcomes. #Hepatocellular @WileyHealth onlinelibrary.wiley.com/doi/10.1002/im…

Sangerbox 2: Enhanced functionalities and update for a comprehensive clinical bioinformatics data analysis platform onlinelibrary.wiley.com/doi/10.1002/im…