iduron

@ScienceMagazine Three magnificent advances to choose from but AI protein structure prediction gets my vote; this is a stunning step forward that will have a major impact on both basic and applied research in the biomedical field.

Choose your favorite for Science’s 2021 People’s Choice award for Breakthrough of the Year. ⬇

Last week, thousands of you told us which discoveries of the past year should make it to the final round of voting for the 2021 #BOTY People’s Choice. Now, who will you choose to win: Will it be ancient soil DNA, in vivo CRISPR, or protein structure prediction by AI? (THREAD) 🧵

We are making good progress in the development of a reliable method for end-labelling heparin, heparan sulphate and other GAGs with biotin. These will be used to make GAG-arrays by attaching them via the biotin tag to 96-well streptavidin-coated surfaces.

Ready for action in the Lake District. Thanks Joe fro Lucy, Sadie and Lola dog

New Dermatan Sulphate isomer with unique DS-E disaccharide unit (IdoA - GalNAc,4S,6S). Available soon. This will complement our range of Chondroitin/Dermatan Sulphate Polymers including CS-E. iduron.co.uk/product/chondr…

Hello; at Iduron we have an extensive range of hyaluronic acid (hyaluronan) oligosaccharides ideal for protein binding studies and for investigating size-related HA conformations iduron.co.uk/product/hyalur…. Coming soon biotinylated HA-oligos.

Heparan sulphate (HS) is active in cell-to-cell transmission of neurodegenerative proteins (tau, A-beta, synuclein) involved in Alzheimers and Parkinsons diseases Paper in BioRxiv by Diamond and co (doi.org/10.1101/207035) shows the importance of HS sulphation in these processes

New Chondroitin Sulphate Polymers - CS-D and CS-E types. Distinctive physical and biological properties. iduron.co.uk/product/chondr…