Inductive Bio

We are excited to announce we have won first place in the OpenADMET-ExpansionRx blind challenge - our second consecutive first-place finish in a major ADMET benchmark. This challenge had 370+ teams competing to predict 9 ADMET properties on over 2,250 unseen compounds from a real drug discovery campaign, rather than retrospective datasets. Beacon’s performance reflects how our virtual chemistry labs are used in practice: helping teams make earlier, higher-confidence decisions around safety, dose, and developability. Thanks to OpenADMET and Expansion Therapeutics for running a rigorous community benchmark, the Inductive team for all the work behind the results, and all our pre-competitive ADMET consortium members who made this possible.

We’re excited to lead a $21M ARPA-H initiative with @Amgen and leading academics to build AI models for drug toxicity - improving drug safety and reducing reliance on animal testing. We’re generating human organoid, microphysiological system (MPS), and ex vivo tissue data to build digital liver & heart models to better predict DILI and cardiotoxicity. inductive.bio/news/inductive…

Can AI fix one of drug discovery’s biggest bottlenecks? At Inductive Bio, we think so, by making ADMET optimization faster and smarter. In this new @DrugTargetRev feature, our CEO Josh Haimson shares how: drugtargetreview.com/article/168391…

We’re thrilled to announce that our latest generation of Beacon-1 ADMET models secured first place in the recent @Polaris_HQ blinded prediction challenge focused on ADMET properties in a real ASAP discovery antiviral program. Read about our lessons learned: inductive.bio/blog/lessons-f…

Big news: Inductive has raised a $25M Series A to democratize AI that transforms small molecule drug discovery. Our Compass platform, powered by our pre-competitive data consortium, predicts ADMET properties before synthesis - helping find higher quality drugs for patients, faster. • Backed by @obviousvc, @a16zBioHealth, @Lux_Capital, @S32_VC & more • 1st place in Polaris ADMET challenge • Supporting dozens of active drug programs already We’re just getting started. 👉 inductive.bio/news/inductive… #DrugDiscovery #AI #Biotech #Pharma #InductiveBio

The rapid rise of AI in drug discovery brings both new opportunities and new challenges to navigate. We’ll be exploring these topics at two sessions at @ACS Spring 2025 this year. Looking to see a demo of Inductive Bio’s latest at #ACS? inductive.bio/book-a-demo

Switching from SMILES to IUPAC reduces invalid molecules generated by LLMs by >90%. Want to know why? Catch up on our blog now: inductive.bio/blog/molecular… #GenerativeChemistry #DrugDiscovery #AI #ML

LLMs’ impact in generative chemistry has been limited to date. We show that a slight change in how you ask the question, simply by switching the input from SMILES to IUPAC, can reduce invalid molecules by >90%. Learn more: inductive.bio/blog/molecular… #GenerativeChemistry #AI #ML

Join us at #ACSFall 2024! Our own Josh Haimson will be host "Sifting Reality from Hype - AI & ML in Drug Discovery" on Aug 20 with experts from Eli Lilly, Atavistik Bio, & Sanofi. Looking to meet with our team while at #ACS? inductive.bio/contact-us

Guidelines for best practices when using #ML for #ADME drug optimization from @inductive_bio & @nestedtx including a successful case study! #ACSMedChemLett go.acs.org/ape

Tired of the local vs. global property-prediction model debate? Why not both? Our blog dives into this debate and provides evidence that a combined global+local approach performs the best. Learn more: inductive.bio/blog/local-vs-… #DrugDiscovery #ML #ADME #Biotech

High value AI application: Predicting properties of new drug candidates. Congrats to the Nested Tx and Inductive Bio teams on this successful collaboration showing how new AI models can predict ADME properties and accelerate small molecule drug discovery.

Thrilled to announce that our work with @nestedtx in drug optimization is now published! 🧬Our ML models helped overcome critical ADME issues to advance Nested’s program. Full story: inductive.bio/news/publicati… #DrugDiscovery #ML #ADME #Biotech

Our latest blog post on Alpha Fold 3 explores how AF3 small-molecule docking compares to existing techniques and shows that the story is more nuanced than headlines suggest. inductive.bio/blog/strong-ba…

Our journey is just beginning! DM us if you’d like to be involved either as a partner or as a member of our team.

We are collaborating with multiple therapeutics companies to validate and deploy our technology, including Denali Therapeutics (NASDAQ:DNLI), who have integrated our models into their small molecule drug design platform to support rapid, data-driven decision making.

We are thrilled to be coming out of stealth! See our press release (prnewswire.com/news-releases/…), along with some coverage from STAT in their Readout Newsletter (statnews.com/2023/12/13/bio…).