Thomas Brody

Mandal, N., Das, A., Datta, R. (2025). Unravelling a mechanistic link between mitophagy defect, mitochondrial malfunction, and apoptotic neurodegeneration in Mucopolysaccharidosis VII. Neurobiology of disease, 206:106825 sciencedirect.com/science/articl…

Prifti, M. V., Nuga, O., ...., Richardson, K., Todi, S. V. (2025). Unravelling a mechanistic link between mitophagy defect, mitochondrial malfunction, and apoptotic neurodegeneration in Mucopolysaccharidosis VII. Neurobiology of disease, 207:106834 sciencedirect.com/science/articl…

Mosley, O. L., Villa, J. A., Kamalakkannan, A., James, E., Hoffman, J. M., Lyu, Y. (2025). Stochasticity in dietary restriction-mediated lifespan outcomes in Drosophila. Geroscience, 47(3):4697-4709 link.springer.com/article/10.100…

Mattins, F., Nagrath, S., Fan, Y., Manea, T. K. D., Das, S., Shankar, A., Tower, J. (2025). Machine Learning Scoring Reveals Increased Frequency of Falls Proximal to Death in Drosophila melanogaster. J Gerontol A Biol Sci Med Sci, 80(6) academic.oup.com/biomedgerontol…

Nedachi, T., Kawasaki, H., Inoue, E., Suzuki, T., Nakagawa-Yagi, Y., Ishida, N. (2025). Electric-field induced sleep promotion and lifespan extension in Gaucher's disease model flies. Biochem Biophys Rep, 41:101915 sciencedirect.com/science/articl…

Hu, C., Xu, X., Hu, X., Zhang, J., Shen, L. (2025). Edible plant oils with high n-3/n-6 polyunsaturated fatty acids ratio prolong the lifespan of Drosophila by modulating lipid metabolism. Food Chem, 474:143121 sciencedirect.com/science/articl…

Heidarian, Y., Fasteen, T., Mungcal, L., Buddika, K., Mahmoudzadeh, N., Nemkov, T., D'Alessandro, A., Tennessen, J. M. (2025). Hypoxia-inducible factor 1α is required to establish the larval glycolytic program in Drosophila. Mol Metab, 93:102106 pubmed.ncbi.nlm.nih.gov/39894213/

Mercola, B. M., Villalobos, T. V., Wood, J. E., Basu, A., Johnson, A. E. (2025). Increased expression of the small lysosomal gene SVIP in the Drosophila gut suppresses pathophysiological features associated with a high-fat diet. Biology open, 14(2) journals.biologists.com/bio/article/14…

Li, J., Dong, Y., Zhou, T., Tian, H., Huang, X., Zhang, Y. Q., Wang, Y., Lam, S. M., Shui, G. (2024). Long-chain acyl-CoA synthetase regulates systemic lipid homeostasis via glycosylation-dependent lipoprotein production. Life Metab, 3(2):loae004 pmc.ncbi.nlm.nih.gov/articles/PMC11…

Bak, N. K., Mackay, T. F. C., Morgante, F., Nielsen, K. L., Nielsen, J. L., Kristensen, T. N., Rohde, P. D. (2025). The Role of Genetic Variation in Shaping Phenotypic Responses to Diet in Aging Drosophila melanogaster. bioRxiv, biorxiv.org/content/10.110…

Alvarez-Rendon, J. P., Riesgo-Escovar, J. R. (2025). The S6 kinase gene in the fruit fly, Drosophila melanogaster, is essential for metabolic regulation. Gen Comp Endocrinol, 362:114672 sciencedirect.com/science/articl…

Kim, S., Park, J. G., Choi, S. H., Kim, J. W., Jin, M. S. (2025). Cryo-EM structures reveal the H(+)/citrate symport mechanism of Drosophila INDY. Life science alliance, 8(4) life-science-alliance.org/content/8/4/e2…

Grmai, L., Mychalczuk, M., Arkalgud, A., Vasudevan, D. (2024). Sexually dimorphic ATF4 expression in the fat confers female stress tolerance in Drosophila melanogaster. bioRxiv, biorxiv.org/content/10.110…

Davies, L. R., Kristensen, T. N., Sorensen, J. G., Loeschcke, V., Schou, M. F. (2025). Nutritional stress in larvae induces adaptive responses that transcend generations in males of a model insect. The Journal of experimental biology, 228(2) journals.biologists.com/jeb/article/22…

Wang, Y., Li, Y., Zang, X., Moussian, B., ..., Sun, S., Yuchi, Z., Liu, X. (2025). Lead (Pb) load interacts with oxidative stress in Drosophila melanogaster through MTF-1/Nrf2/JNK mediated metallothionein expression. Ecotoxicol Environ Saf, 292:117921 sciencedirect.com/science/articl…

Meraner, P., Avetisyan, A., Swift, K., Cheng, Y. C., Barria, R., Freeman, M. R. (2025). Hypoxia-inducible factor 1 protects neurons from Sarm1-mediated neurodegeneration. bioRxiv, biorxiv.org/content/10.110…

Widuch, M. J., Siepka, S. M., Carthew, R. W. (2026). Insulin Signaling Functions as a Topological Switch That Couples Aging and Heat Stress Responsiveness. bioRxiv, biorxiv.org/content/10.110…

Biel, N., Rashid, F., Natua, S., Wang, T. Y., Chou, T. F., Nguyen, T. V. P., Golding, I., Kalsotra, A., Sokac, A. M. (2025). Reducing Cofilin dosage makes embryos resilient to heat stress. bioRxiv, biorxiv.org/content/10.110…

Dyson, A., Gajjar, G., Hoffman, K. C., Lewis, D., Palega, S., Rangel Silva, E., Auwn, J., Bellemer, A. (2025). A nociceptor-specific RNAi screen in Drosophila larvae identifies RNA-binding proteins that regulate thermal nociception. PeerJ, 13:e18857 peerj.com/articles/18857/

Lane, A. R., Scher, N. E., Bhattacharjee, S., Zlatic, S. A., ...., Roberts, B. R., Werner, E., Faundez, V. (2025). Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration. Mol Biol Cell, 36(3):ar33 molbiolcell.org/doi/10.1091/mb…