Wolfgang M. Pernice

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Wolfgang M. Pernice

Wolfgang M. Pernice

@joungMax

Asst. Prof | Laboratory for Digital Biology (LDB) @ the Merritt Center | Columbia University | ML + Rare diseases | More info: https://t.co/lDpSCTF47C

New York City Katılım Eylül 2010
639 Takip Edilen235 Takipçiler
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Wolfgang M. Pernice
Wolfgang M. Pernice@joungMax·
My CVPR highlights🧵- but first some shameless promo: our paper on Interventional Style Transfer (IST) for OOD generalization is out! We argue real-world applications of ML/AI require robust OOD generalization & propose strategies to assess + improve: arxiv.org/abs/2306.11890
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David R. Liu
David R. Liu@davidrliu·
Below is the story of the first patient treated with a prime-edited therapeutic, developed by @PrimeMedicine in a trial led by Dr. Élie Haddad and his team at CHU Sainte-Justine. This teenager suffered from chronic granulomatous disease (CGD), an immunodeficiency, and now—10 months after treatment—the patient is healthy, stable, and living with a functioning immune system. Tracy Attebury, whose story was previously told by @ginakolata @nytimes, was the second patient treated with a prime-edited therapeutic. cihr-irsc.gc.ca/e/54638.html
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Wolfgang M. Pernice
Wolfgang M. Pernice@joungMax·
Been saying for years that AR+moldynamics could allow us get a "feel" for how a molecule behaves i.e. unlocm a whole new way to understand molecular bio by plugging into the human ability to process tactile information. These guys have built it! Super cool, can't wait to try.
Fabio Cortes@fabiojcortes

Five years ago, if someone had said my final task at @EPFL would involve prototyping a UI for molecular dynamics in AR, I would've called them crazy. And yet, here we are, pushing the limits of what a web browser can do! Built with @threejs and UIKit by @pmndrs

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Ashlee Vance
Ashlee Vance@ashleevance·
Watcha guys think? $2,500 to have one of my books sucked into an LLM. Yes, no?
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Elon Musk
Elon Musk@elonmusk·
What a huge liar. The AfD policies are identical to those of the US Democratic Party when Obama took office! I don’t think there is a single difference.
Western Lensman@WesternLensman

🚨Sen. Chris Murphy just went on CNN and accused @elonmusk of "endorsing a neo-N*zi party” over Elon’s support of German political party AfD. This is an insanely dishonest smear. Murphy went on to fearmonger about the possibility of Trump supporting neo-N*zis: "What we know is that what Elon Musk thinks tends to eventually be what the president of the United States thinks. And if the United States takes an official position in favor of neo-N*zis in Germany. I mean, it is absolutely catastrophic." Democrats also called Trump H*tler and Republicans n*zis for the last four years, to put this outrageous slander into perspective.

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Wolfgang M. Pernice
Wolfgang M. Pernice@joungMax·
An incredible opportunity to join a world leading team and push the frontiers in unsupervised deep learning across many high-impact scientific domains! 🔬🛰️🧪🤖
Piotr Bojanowski@p_bojanowski

🔥Our team working on unsupervised deep learning is looking for a PhD intern for 2025. We are looking for deep learning / machine learning PhD students! If you are interested, you can apply here: metacareers.com/jobs/843046771… Don't hesitate to reach out!

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Wolfgang M. Pernice retweetledi
Rachel Tobac
Rachel Tobac@RachelTobac·
LinkedIn is now using everyone's content to train their AI tool -- they just auto opted everyone in. I recommend opting out now (AND that orgs put an end to auto opt-in, it's not cool) Opt out steps: Settings and Privacy > Data Privacy > Data for Generative AI Improvement (OFF)
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Wolfgang M. Pernice
Wolfgang M. Pernice@joungMax·
And the name of the judge who just ruled Google a monopoly is... 🥁
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Daniel MacArthur
Daniel MacArthur@dgmacarthur·
On April 8, @nickywhiffin posted a preprint on a new non-coding gene for intellectual disability; 3 days later another group submitted the same thing to @NatureMedicine with less data. It’s just published, no citation to the preprint. I thought genomics was past this grubbiness.
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Wolfgang M. Pernice
Wolfgang M. Pernice@joungMax·
@seldo That's what I do. Typically I only practice a few intro sentences to get going. I do spend a fair bit of time designing each slide and flow though so that by the end, the story tells itself.
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Laurie Voss
Laurie Voss@seldo·
Apparently a thing some people routinely do is make a bunch of slides and then just roughly remember what they were going to say in response to each slide without speaker notes, I cannot imagine being able to do that.
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Wolfgang M. Pernice
Wolfgang M. Pernice@joungMax·
That's a wrap on @NVIDIAGTC for me. It was a celebration of the immense potential of AI to empower human thought and capability - nowhere in my view is this potential greater than in its application to biology. The strong representation (and Jensen's support) of #DigitalBiology / #AIxBioMed at GTC speaks to it.  But what's also clear is that too many current efforts here stay entirely in hypothesis-land. There is no way around the hard work of wet-lab experimental validation. Aviv made the case for the lab-in-the-loop like only she can. But let's go further: let's not only have the lab, but the patients themselves in the loop.  If you want to learn more / committed the terrible sin of missing my talk, check out my presentation on Digital Biology for #RareDisease in about a month on the GTC platform (or just dm me 😊).
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Wolfgang M. Pernice
Wolfgang M. Pernice@joungMax·
@NVIDIAGTC", @CathieDWood invokes an old madman joke "Half of our advertisement works. We just don't know which one". How much worse are we in biomedicine? The promise of #digitalbiology is to (1) measure this, and (2) bring the fraction that works to 100% 🚀
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Wolfgang M. Pernice
Wolfgang M. Pernice@joungMax·
Simulated worlds and using LLMs to create reward functions to learn behaviors via RL too complex to engineer by hand is @DrJimFan recipe towards embodied AI.
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Wolfgang M. Pernice
Wolfgang M. Pernice@joungMax·
Inbound for @NVIDIAGTC. Catch my talk "Computer Vision for Rare Disease Genomic Medicine (S62535)" on Thursday morning.
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Max Jaderberg
Max Jaderberg@maxjaderberg·
New week, new opening! We are looking for machine learning scientists to create the next generation state-of-the-art models for computational biology. There's so much tantalizing potential, exemplified by incredible recent works like Enformer, Evo, AlphaMissense, to create a step-change in our understanding of biology, by building closely with our other ML and CompBio teams at @IsomorphicLabs boards.greenhouse.io/isomorphiclabs…
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