#Echidna is now publicly available at github.com/azizilab/ech..., and may also be installed through PyPI and Bioconda! We hope you will join us in understanding the role of CNAs in phenotypic plasticity!
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Joy Fan
15 posts
Joy Fan
@joy_lfan
PhD candidate in BME @Columbia | computational #cancer research at https://t.co/E6PINqiCXX
Katılım Ocak 2023
62 Takip Edilen70 Takipçiler
📢 TL;DR: #Echidna 🦔integrates scRNA-seq & WGS to decouple gene dosage effects on phenotypic plasticity, tracks clonal evolution, and identifies resistance drivers in tumors.
Read more here: biorxiv.org/content/10.110…
Let’s unravel tumor evolution, one clone at a time! 7/7
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🧵 Excited to share #Echidna, a Bayesian framework for quantifying the impact of gene dosage on phenotypic plasticity: tinyurl.com/296kf7hf!
With @elhamazizi & @mingZedh, we integrate scRNA-seq & WGS to uncover how CNAs drive tumor evolution and transcriptional variability.
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Joy Fan retweetledi
Check out our comment piece with @joy_lfan @AchilleNazaret on breakthroughs in #AI for studying the tumor microenvironment. Thanks to @naturemethods for the opportunity!
@ColumbiaBME @Cancer_dynamics @CUSEAS @columbiacancer
Nature Methods@naturemethods
A Comment from @elhamazizi and colleagues discusses how AI methods will enable the interpretation of high-dimensional cancer data to provide new insights into our understanding of tumor progression and resistance. nature.com/articles/s4159…
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So thankful for this opportunity and for the support of @Cancer_dynamics and @elhamazizi ☺️
Columbia - Irving Institute for Cancer Dynamics@Cancer_dynamics
Thrilled to announce that Linyue (Joy) Fan @joy_lfan, PhD student in biomedical engineering, @elhamazizi, has been awarded the prestigious #AvanessiansFellowship for the 2024 Spring semester! 🏆 Join us in congratulating Joy on this recognition! 👏
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So grateful to collaborators @AchilleNazaret @elhamazizi @vp_lavallee @dana_peer for leading this project with me, and many others for their contributions!
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Unveiling the power of #Decipher , a game-changing method for integrating and visualizing #singlecell RNA-seq data! 👩🔬 Our work sheds light on cell-state transitions in diseases like #AML. Join the conversation in the thread and check out our preprint for the full story!
Achille Nazaret@AchilleNazaret
1/🧵 Excited to share #Decipher 🔍, a game-changing method for integrating #singlecell RNA-seq data 🧬 from multiple conditions and revealing cell-state transitions in diseases like #AML. Dive into our thread for more! Check our preprint for full details. biorxiv.org/content/10.110…
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Joy Fan retweetledi
In the latest "Faces of IICD" blog series, Joy Fan (@joy_lfan) shares about balancing out multiple roles as a musician, artist, writer, and scientist.
Link: bit.ly/46goyv9
cc: @elhamazizi @ColumbiaBME
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Joy Fan retweetledi
Researchers @Columbia have invented a multimodal RNA sequencing method that achieves high-quality results from small volumes of frozen cancer tissues. engineering.columbia.edu/news/multimoda… @ColumbiaMed @ColumbiaScience @ColumbiaBME @elhamazizi @BizarMd @joy_lfan @JCA_Melms
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Joy Fan retweetledi
Our first (of many to come😃) exciting collaborative effort(s) with the @BizarMd Lab, led by superstars Yiping Wang @joy_lfan @JCA_Melms bringing multimodal single-nucleus RNA/TCR, spatial and whole-genome seq to the #clinical arena!
#cancergenomics #computationalbiology
Nature Genetics@NatureGenet
‼️ JUST PUBLISHED @NatureGenet 📰 Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens 🧑🏿🤝🧑🏿 @elhamazizi Ben Izar and team 👇🏼 go.nature.com/3VZKkwy
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