Knowuro

Another 30 cases are live in the app, bringing the total to 60! 🤩 Whether you are new to urology, or resident preparing for your board exam, these cases are a great way to test yourself. “Urology in Practice” is a unique digital book including imaging. knro.link/l6fvsj8p

🩻Contrast-induced AKI: one of the biggest myths still shaping clinical decisions For decades we were taught: 👉 “Contrast damages the kidneys” 👉 “Avoid CT with contrast in CKD” 👉 “Hydrate, protect, delay imaging if needed” But what if… most of this is wrong?🤔 ->The uncomfortable reality Modern evidence shows: 👉 Low-osmolar contrast rarely causes true nephrotoxicity 👉 Even in CKD, AKI, and ICU patients 👉 The risk is often overestimated—or nonexistent So where did the fear come from? 📍 1950s high-osmolar contrast (actually toxic) 📍 Poorly controlled observational studies 📍 “Creatinine rise = contrast injury” assumption 👉 Correlation became causation 👉 And the dogma stayed ⚠️What recent data tells us ✔ No difference in AKI rates with vs without contrast ✔ No benefit from bicarbonate, NAC, or aggressive hydration ✔ Even ICU and AKI patients show no worsening outcomes ->Translation to real life 👉 The patient was going to develop AKI anyway...Not because of contrast!! ->The real problem: “Renalism” 👉 Avoiding necessary imaging 👉 Delaying diagnosis 👉 Choosing inferior tests And that leads to: ❌ Missed PE ❌ Delayed sepsis source control ❌ Worse outcomes ->Clinical mindset shift Instead of asking: 👉 “Will contrast harm the kidneys?” We should ask: 👉 “Will NOT doing the scan harm the patient?” ->Who still deserves caution? ✔ eGFR <30 ✔ Severe hemodynamic instability ✔ Multiple nephrotoxins Even then: 👉 Optimize volume 👉 Minimize dose 👉 Don’t delay critical imaging 🤓Bottom line ✔ Contrast nephrotoxicity exists… but is rare ✔ The fear is bigger than the risk ✔ The harm of NOT imaging is often greater In critical care 👉 We don’t treat creatinine 👉 We treat patients And sometimes… 👉 The most dangerous thing is NOT the contrast 👉 It’s hesitation. 📃Reference Florens N, Demiselle J. Kidney360 7: 445–449, 2026. doi: doi.org/10.34067/KID.0…

Hey urologists, time to get your favourite playlist ready 🎶

Another UROfact for the week! Phosphodiesterase type 5 inhibitors include: sildenafil, tadalafil, vardenafil, and avanafIl. Sources: knro.link/sld7q7io and knro.link/y32rkkwk

Thank you for the overwhelming support! We are excited to begin work on the new edition! If you need access to the content of the last review 25, it is still available in our App.

Urofact of the day! #urology

@Nuzhat_FH @amorgado4 @andrea_cocci Hello! No, we only have it as book or on our App.

@knowuro @amorgado4 @andrea_cocci Hi. Do you have pdf of unboxed?

Finally, it’s here! 🎉 The 2025 edition is now ready to order 👉knro.link/gx1s2a2r Thrilled to welcome @amorgado4 and @andrea_cocci to our reviewers’ board. A big thank you to all our reviewers for their dedication in bringing this new edition to life! 📚✨

Great review of the complications associated with an ileal conduit. 👌

Yuhuu! 🎉 Our new book Urology in Practice is out! The first 30 study cases to practise are now live on our app — 70 more on the way! A big thank you to @Mohamedendourol for contributing images to some of the first cases! 🙏 👉knro.link/6mo1siin

Hello! 👋 Diagnosing a colovesical fistula is often challenging and often requires multiple invasive and costly tests. The poppy seed test, however, should not be overlooked—it is cheap, accurate, and an ideal initial consideration for evaluating a suspected colovesical fistula.

@ankitraj0019 Our plan is to release the first batch of cases in October, and then gradually add more over time.

@knowuro Any tentative date when it'll arrive? I've exams in November and have already subscribed the app. Thanks

Our 📚 library is growing 👀 We are working on our next book: Urology in Practice. A collection of cases structured for learning step-by-step and sharpening your skills — ideal for preparing before oral exams like FEBU part 2. Coming very soon!

Hello! 👋 Spinal cord compression is a cancer emergency 🚑 seen in up to 20% with vertebral mets. Prostate cancer causes blastic (radio-opaque, painful, fewer fractures) METs, while renal cancer causes lytic (bone loss, fracture-prone) METs.

Hello! 👋 This year, Spanish translations of our uro-oncology flowcharts were created as learning materials for the CONTIGO course in Spain. They are freely available on our website for Spanish-speaking doctors. 🙂👇 knro.link/7dtvvn5q

While updating the PCA chapter of my book Urology: the Last Review (@knowuro) with @JGomezRivas, we came across something worth diving in – the new EAU risk classification for PCA. Want to know more? Freshly published in European Urology. See link 👇 knro.link/m8t99c5y

📢 New in European Urology: SABR is not just for brain mets. A systematic review shows excellent results in RCC—alone or with IO. 🧠 Local control in primary RCC 🛡️ Delay of systemic therapy in oligomets ⚡ IO + SABR: promising combos 🔗 buff.ly/5XN3Ejr #RCC #SABR #Immunotherapy #UroOncology

We’re a small team of 2, and life brought a beautiful surprise recently 🍼 Because of that, Urology: the last review 2025 will arrive a little later than planned. For those eager for updates, you can find the latest content inside the app. Thank you for your patience and support!

It’s here🥳 #urology: The Last Review 2025 is now available in our App! Just in time for #FEBU🤩 Updated with the 2025 Guidelines, 2 new reviewers, 1 new chapter (Urethral strictures) and improvements thanks to our readers🤓 Paper edition in late-July. knro.link/yy1mbi27

#Urologists often overlook bowel symptoms after RC—especially in younger patients and those with neobladders. These symptoms can seriously impact quality of life. Don’t forget to ask. Don’t forget to manage.