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Kyle Helzer
125 posts

Kyle Helzer
@kylehelzer
Bioinformatics scientist in the Zhao lab @UWHumOnc. PhD in Cancer Biology from @UWMadison. @UMich alumnus. Scientist by day, piano junkie by night.
Katılım Mart 2016
219 Takip Edilen76 Takipçiler

@glass_heff_full I can relate.
Had some copies of mine printed for committee members and then noticed on the cover page I had written UNIVERSITY OF WISCONSON
Congrats on submitting though!
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@kimthi1011 @tangming2005 This will also depend on what kind of samples you are working with. If you expect a high amount of contaminating seqs then the assigned % will be lower. I've found that looking at the breakdown of Unassigned reads (Ambiguity, NoFeatures, Unmapped, etc.) is informative too for QC
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@kimthi1011 @tangming2005 This is something I have wondered as well. Generally we seem to get meaningful results with assigned reads >50%. Comparing assigned read % across all samples and identifying low % outliers could also be a useful strategy rather than setting a strict cutoff.
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What is an acceptable range (%) for successfully assigning mapped reads to genomic features? I'm using featureCount (after alignment with STAR). My data is paired-end, reversely-stranded. #Bioinformatics #ngs @tangming2005
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@TheStatsMedic Nope, currently editing a scientific manuscript and I thought you would be a great resource to weigh in on some stats nomenclature :)
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@kylehelzer You teaching now? #formerstudent
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@TheStatsMedic What is the capitalization rule for reporting test stats? i.e. t-test vs. T-test, t-statistic vs. T-statistic, z-score vs Z-score, etc...? I am seeing both and not sure what is standard.
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Kyle Helzer retweetledi

This graph really highlights the importance of keeping up social distancing and mask wearing in (at least) the first two weeks following the first dose of the vaccine. You don't get immunity right away.
Vaccine = blue 🔵
Placebo = red 🔴
Florian Krammer@florian_krammer
No words needed. That's what vaccines do.
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When your miso actually cites their claims
(Here's the paper: academic.oup.com/jnci/article/9…)

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Kyle Helzer retweetledi

📩Stuffed:✔️
🦭 Sealed: ✔️
📬Stamped: ✔️
📨Delivered: 🔜
This is probably about 5% of the ballots to be sent out in the first batch, going into the mail today. Many more to follow. If you have requested your ballot, check the status at myvote.wi.gov/en-us/VoteAbse…. #MadisonVotes2020

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Live look at UW-Madison telling the students that all their social gatherings are cancelled and that they must severely limit in-person interactions
youtu.be/EuZeff2y32M

YouTube
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@AndrewHolding @markowetzlab Haha, here you can have some of mine:
!!!!!!!!!!!!!!!!!!!!
!!!!!!!!!!!!!!!!!!!!
!!!!!!!!!!!!!!!!!!!!
!!!!!!!!!!!!!!!!!!!!
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She truly is the best. Beautiful speech
Michelle Obama@MichelleObama
If we want to end the chaos and division—and keep alive the possibility of progress on the issues we hold dear—we’ve got to vote for @JoeBiden and @KamalaHarris like our lives depend on it. Register today by texting VOTE to 30330. pscp.tv/w/cgnnAzF3QktB…
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Another amazingly salient piece from @edyong209. It's gut-wrenching to see how many things could have been done better. theatlantic.com/magazine/archi…
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Kyle Helzer retweetledi
Kyle Helzer retweetledi

We are really excited that our work showing how pervasive lesion segregation shapes cancer genome evolution is published today in @nature.
nature.com/articles/s4158…
Here’s a #tweetorial to explain our #LesionSegregation findings...
[1/13]
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@AndrewHolding @Kat_Arney @edyong209 @HopeJahren @DrSidMukherjee @Lone_Frank @SideshowAmi @GeneticsUnzip @RebeccaSkloot If she has an interest in chemistry, then I would recommend The Disappearing Spoon by Sam Kean. It details the stories behind the discoveries of each element on the periodic table
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