serranoLab

Cancer dysregulates thousands of exons; some are drivers and could lead to therapies. But which ones? Similar to VEP models for mutations, we model potential cancer driver exons genome-wide and predict exon fitness in cancer. @NatureComms: doi.org/10.1038/s41467… 🧵

It was really great to work with Yamile and Luis (@lab_serrano) on this project! Check out our article if you want to know more about how to expose or secrete proteins with Mycoplasma pneumoniae: doi.org/10.1186/s12934…

OBS #Genomics Seminar 📆 Thursday, 9/26, 11 am ET/5 pm CET 🎙️ Miquel Anglada Girotto (Centre for Genomic Regulation) 🎙️ Xavier Hernandez Alias 👉 Registration: us02web.zoom.us/meeting/regist… #openscience Moderator: @asalboix

Cancer dysregulates thousands of exons; some are drivers and could lead to therapies. But which ones? Similar to VEP models for mutations, we model potential cancer driver exons genome-wide and predict exon fitness in cancer. @NatureComms: doi.org/10.1038/s41467… 🧵

Can we measure changes in splicing factor “activity”? 🤔 In complex samples like cancer, it's tricky because SF activity is regulated by more than just expression changes or mutations. Check out our new collab between @lab_serrano and @califano_lab: t.ly/mitjX 🧵

🎓 Eight doctoral students from the PhD Programme in #Biomedicine will receive the @UPFBarcelona Doctoral School PhD Extraordinary Award Congratulations to you all! 👏🏽💐💫 Have a look at their projects following this thread 👇🏽 👉🏽tuit.cat/iz7Wy

😶‍🌫️😶‍🌫️😶‍🌫️HAVE YOU EVER DREAMED OF IDENTIFYING MULTIPLE PROTEOFORMS OF YOUR PROTEIN OF INTEREST IN A SINGLE IP-#mass_spectrometry?💥💥💥 @KourtisSavvas from our lab found the way 🤩 👇👇 doi.org/10.1101/2024.0…

Read the preprint bit.ly/3QpiUk1 describing a milestone in our de novo antibody design efforts. Our pipeline can now design high-affinity and stable antibodies in a single round! Fantastic collaboration with @lab_serrano @SavvidesLab & Maarten Dewilde @KU_Leuven