Lawrence Hsu Lin

Uterine teratomas: a report of clinicopathological features of five tumours - Lin - 2026 - Histopathology - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/hi… @lawrencehlin

Harvard Medical School and MGH pathology course… 5 full days from experts!

Nothing makes us prouder than seeing our alumni return to teach the next generation! Huge thanks to Dr Lawrence Lin for coming home to lead an incredible Grand Round and Unknowns session. His brilliance, warmth, and teaching made our day! @lawrencehlin💜 @NYUGSOM_Path #pathology

@NYUGSOMpathres @NYUGSOM_Path It was such an honor for me to be back at NYU and see my mentors and colleagues again. The residents did an amazing job at the unknowns 💜

Part 2/2 🔬 Fig 1: Higher power view of atypical stromal fragment on biopsy 🔬Fig 2-3: Hysterectomy confirming biphasic malignant neoplasm 💡Diagnosis: Carcinosarcoma Always have carcinosarcoma in the back of your mind in high-grade mullerian carcinoma of ambiguous morphology

Part 1/2 🩺 Postmenopausal bleeding 🔬 Endometrial biopsy Fig 1-3: Adenocarcinoma of ambiguous morphology Fig 4: Single fragment of atypical stroma (after searching for a while) IHC: P53 overexpressed, intact MMR #PathTwitter #pathology #GYNPath #endometrialcancer

🩺 Postmenopausal bleeding + ovarian mass 🔬 Fig 1: Endometrial adenocarcinoma Fig 2-3: Lobulated and nested ovarian tumor (H&E) Fig 4: Nested architecture (reticulin stain) 💡 Diagnosis: adult granulosa cell tumor + endometrial adenocarcinoma #PathTwitter #pathology #GYNPath

🎭The many faces of Mullerian carcinosarcomas🎭 Fig 1: Pleomorphic sarcoma + high grade carcinoma Fig 2: Chondrosarcoma + high grade carcinoma Fig 3: Rhabdomyosarcoma Fig 4: Liposarcoma + high grade carcinoma #PathTwitter #pathology #GYNPath #endometrialcancer #PathArt

🧿 In the eye of the storm 🌀 🔬Peritoneal fluid involved by high grade serous carcinoma #PathTwitter #GYNPath #CytoPath #pathology #ovariancancer

Placental site trophoblastic tumor (PSTT) 1 - malignant intermediate trophoblast dissecting the myometrium (solid arrow) and remodeling vessels (dashed arrow) 2 - highly atypical cells w/ abundant eosinophilic cytoplasm 3 - Ki-67/Mel-CAM dual IHC #PathTwitter #GYNPath

Check out this nice review focusing on pathology of subinvolution: pubmed.ncbi.nlm.nih.gov/17090198/ #PathTwitter #GYNPath #OBPath

🩺 Hysterectomy due to hemorrhage 2 weeks after delivery 🔬 1/2. Myometrial dilated vessels adjacent to involuted arteries 3/4. Subinvoluted arteries with hemorrhage and rimming of extravillous trophoblast 💡Diagnosis: Subinvolution of placental site / uterine vessels

🩺 Oligomenorrhea, hirsutism and ovarian mass. 🔬 1/2 Poorly diff. neoplasm w/ multilobular architecture and spindled & epithelioid cells 3/4 Two cell types:💜 Sertoli + 🩷 Leydig cells 💡 Diagnosis: Sertoli-Leydig cell tumor with hormonal production #PathTwitter #GYNPath

@VaishaliPansare P40 is positive in the HSIL areas and negative in the spindle and pleomorphic areas.

@lawrencehlin Curious- did you do p40 or p63?

🩺 Young woman with mass in the cervix. 🔬 Biphasic tumor: 1) HSIL with invasive squamous cell carcinoma 2) Spindled and pleomorphic areas 💡Diagnosis: HPV-related cervical sarcomatoid squamous cells carcinoma #PathTwitter #Pathology #GYNPath #cervicalcancer #HPV

🔬Pollock in H&E - Foreign material in vessel after uterine artery embolization for hemorrhage 🎨 Shimmering substance (1946) by Jackson Pollock - Oil on canvas @MuseumModernArt #PathTwitter #PathArt #pathology #GYNpath #modernart #Pollock

📸 Snapshot of endometrial cancer progression on a single slide: 1) Inactive endometrium ➡️ 2) Endometrial intraepithelial neoplasia/atypical hyperplasia ➡️ 3) Well differentiated endometrioid carcinoma➡️ 4) Dedifferentiated endometrial adenocarcinoma

#PathTwitter #pathogy #GYNpath #OBGYN #encephalitis #autoimmunity

🩺Young woman with ovarian masses and neuropsychiatric symptoms. 🔬Ovarian masses show multiple types of tissue, including mature neural tissue with prominent lymphoplasmacytic infiltrate. Diagnosis: Anti-NMDA receptor encephalitis associated with ovarian mature cystic teratoma

@AaronGoodman33 Also the non classic class I, particularly “trophoblastic” HLA-G and HLA-E