Lynn D. Cornell, M.D.

🔓 Open Access "The Banff 2024 Kidney Meeting Report: Rejection as a spectrum of phenotypes and focus on differential diagnostic reasoning," Naesens et al. amjtransplant.org/article/S1600-… #Transplantation #KidneyTransplant #Banff #TransplantPathology #DifferentialDiagnosis #OpenAccess

@BradenMannsYYC 👏 👏 👏

At a Kidney Foundation event, honoring employers who cover the full salary of people who donate their kidney. Removing just one of the barriers to donation. Steve McCardy accepting on behalf of UCalgary. Way to go!

Comprehensive review on the spectrum of tubulointerstitial disease from @ldcornell kidney-international.org/article/S0085-… in Kidney International @Kidney_Int

@MPerazella @hswapnil @JohannMorelle @Kidney_Int Thank you both!

@hswapnil @JohannMorelle @ldcornell @Kidney_Int Outstanding paper on tubulointerstitial disease.

@grace_choung @set_fortess @MayoClinic 👏

#ULTRAPATH26 Dr Galeano @MayoClinic - Distribution of Iron Deposition in Renal Hemosiderosis: Evidence of Multicompartment Involvement Hemosoderosis can extend beyond proximal tubules #renalpath #ultrastructuralpath #EM

@grace_choung Taxonomy before ontology, a time-honoured tradition. I haven’t seen convincing evidence that “PIG” is a separate entity from membranous GN.

#ULTRAPATH2026 Dr. Joh lecture on podocyte unfolding glomerulopathy (PIG). New subclasses introduced! #EM

The Cornell Travel Grant With generous support from @ldcornell, RPS is pleased to offer 2 travel grants for the 2026 Banff Conference. Applicants should be RPS members; non-members may apply for membership when submitting: renalpathsoc.org/Join-RPS #renalpath

@SaynaNorouzi Sorry to miss the poster in person. Given the prior steroid exposure, I wouldn’t call this true “monotherapy”. This case would support initial steroids to suppress inflammation in the setting of very “active” disease, followed by anti-B cell therapy for long term management.

Sharing our poster on Inebilizumab monotherapy for Immunoglobulin IgG4-Related Kidney Disease #IgG4RKD. In the #MITIGATE trial, #Inebilizumab, was used adjunctively with pred taper. Our case report demonstrates potential efficacy of Inebilizumab as standalone therapy, achieving disease remission without prednisone. While acknowledging the inherent limitations of n=1 data, this offers preliminary insights into possible steroid #sparing regimens in some patients, needing further data with large clinical studies. #Nephrology #RareKidneyDiseases #IgG4RD #WCNISN @ISNWCN

@sam_albadri @Renalpathsoc @MayoClinicPath @MayoClinicNeph Love this! Well said Sam.

Even in the presence of immune complex deposits within the glomerular basement membrane, we are reminded that beyond the science, there is always compassion guiding our diagnosis. Pathology teaches us that even in complexity and injury, there is structure, meaning, and purpose, and at the center of it all, a heart committed to healing.

The Banff 2024 meeting report is official! Link to the article (free access) is below- now get ready for the next Banff meeting, October 5-9, 2026, in beautiful Banff, Alberta, Canada!! authors.elsevier.com/sd/article/S16… @Renalpathsoc #renalpath

@sam_albadri @MayoClinicPath @MayoClinicNeph @Renalpathsoc Congratulations!!! 🥳

Congratulations to Dr. Belinda Galeano on winning Best Abstract at the 6th International Renal Pathology Conference (#IRPC2026) in Antigua, Guatemala! 🏆🎉 Her outstanding work on single-cell spatial transcriptomics and macrophage biology in antibody-mediated rejection continues to advance the field of transplant pathology. So proud of our former Renal Pathology fellow! 👏🧬 #RenalPathology #KidneyTransplant #TransplantImmunology

@JZRenalPath @sam_albadri @Renalpathsoc The Banff scores are diagnosis-agnostic. I think the A/C indices (at least initially) should just apply to rejection… in the Banff post meeting survey, only 66% said that we should consider reporting these indices on all cases.

@ldcornell @sam_albadri @Renalpathsoc We have not yet started. But see potential value. I like the idea of "diagnosis" agnostic indices.

Insightful session on incorporating Activity & Chronicity Indices into the Banff classification for kidney allograft biopsies. Standardizing inflammation and chronic injury scoring may enhance prognostication and therapeutic decisions. Kudos to Dr. Serena Bagnasco and Dr. Muthukumar for an excellent, thought-provoking lecture 👏 Are you currently integrating Activity/Chronicity indices into your renal pathology reports? If so, how has it influenced clinical management? #Banff #RenalPathology #KidneyTransplant #Nephrology

Nice example of pigmented nephropathy (likely myoglobin cast nephropathy) in an autopsy case (sepsis). I find this is a frequently overlooked finding in autopsy cases. Trichrome highlights the casts bright red. Can also do myoglobin stain to confirm. #renalpath #autopsypath

@shary_tang @JZRenalPath pubmed.ncbi.nlm.nih.gov/12605360/ is this the lesion you’re referring to? Mark Haas had a nice paper on it!

@JZRenalPath Singular subepithelial EDD laden with spherions are commonly seen at the folds of the GBM near mesangial area. Infection related?

Rare thin GBM segments can be seen cases of advanced diabetic glomerulopathy (1-5% of surface areas); otherwise thickened GBM. Thought to represent new vessel formation; not to be confused for COLIV related disease. #renalpath #nephrology #pathtwitter pubmed.ncbi.nlm.nih.gov/2456298/

Why is IgG4-related kidney disease overlooked or misdiagnosed? #renalpath @Renalpathsoc @VuMedi @IgG4ward #IgG4 vumedi.com/video/why-igg4…

Not all glomerular disease is the same. Yet many kidney transplant trials still exclude these patients altogether. Fresh off the press! kireports.org/article/S2468-…

Reminder to review non-neoplastic tissue in tumor nephrectomies. #renalpath always takes a quick look here. Slightly tedious but can be very useful. RCC pt with amyloidosis. Amyloid A IHC positive (can be seen with RCC); mass spec pending. #nephrology #pathwitter #nephrology

UCalgary claims top five spot in national research rankings. How does this impact you and your community? ucalgary.ca/top-five

RPS and Banff Activity/Chronicity Working Group WITH REGISTRATION LINK us02web.zoom.us/webinar/regist…