Liam retweetledi

Do GLP1s cause pancreatitis?
I ran the systematic review and meta-analysis: 31 RCTs with 40,274 patients
Results:
Placebo — 50 cases/17433 patients
GLP1 (Semaglutide or Tirzepatide) — 59 cases/22841 patients
OR 0.99 (95% CI 0.67-1.45)
Conclusion: There's no obvious pancreatitis safety signal in these pooled randomized data, but the overall incidence of acute pancreatitis was very very low

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