Lukas Sveikata, MD

Check out our new piece on #CAA #AD interplay and implications for #amyloid clearing and #aducanumab, published today @StrokeAHA_ASA. Screening for CAA might be 🔑 to reduce ARIA risk. Thankful🙏 to my mentors Dr Viswanathan @a_charidimou @SMGreenbergNeur doi.org/10.1161/STROKE…

Last chance to apply until June 30 to YouCliN Research, Thesis, And Education Awards ! Link👇

#MondayTip 📊Pooled INTERACT data ✅Intensive BP lowering improves recovery in ICH ⏱️When started <3h (cutoff: 2.6h)➡️reduces haematoma growth ☝️Greatest benefit in mild–moderate ICH (ICH score) 🚨Early treatment improves outcomes👉supports CODE-ICH systems & future trial design

News from the Swiss Stroke Registry by ⁦@mbgoeldlin: DWI-lesions in ICH are frequent, already on admission before any intervention; associationbwith CAA and SVD burden. Suitable surrogate outcome in trials?@StrokeBern⁩ ⁦@GreenJournal⁩ neurology.org/doi/10.1212/WN…

Still time to apply for YouCliN awards before June 30 !

We invite you to apply for the one-month YouCliN NeXus Clinical Fellowship Award, a great opportunity for early-career clinician-scientists in Switzerland to enhance their clinical neuroscience expertise. Apply now! 🔗sfcns.ch/youclin/about-…

🧠🩸White matter hyperintensities are independently associated with systemic vascular aging and cerebrovascular dysfunction journals.sagepub.com/doi/full/10.11… @alastair_webb

We explore the kidney-immune-brain axis in this latest paper, focusing on mechanisms of inflammation in CKD, its impact on stroke pathogenesis, prognosis & the potential role of anti-inflammatory agents ahajournals.org/doi/10.1161/ST… @StrokeAHA_ASA @EoinKr @NDCNOxford @QueensCollegeOx

🌟Update on basilar artery occlusion stroke by Prof Patrik Michel (CHUV). 💡Revascularisation is crucial for BAO like a parachute jumping from a plane BUT it’s subject to the height/severity of the fall/stroke! 💫Swiss Stroke Society meeting @inselgruppe

#STROKE: This narrative review by Mai et al. critically appraises the literature on recovery trajectories after intracranial hemorrhage as compared with acute ischemic stroke. #AHAJournals ahajrnls.org/3C3DBOs @ArKatsanos @Ash_Shoamanesh

#STROKE: Longitudinal changes in CBF and cerebrovascular resistance index may have bidirectional relationship with development of subclinical vascular brain disease in older adults. #AHAJournals ahajrnls.org/420isiN @YuanMaHSPH @fjwltrs @WiroNiessen @HarvardEpi @univgroningen

@Laura_Sofia_S @_michael_scholl @EllenSingletonn Congratulations Laura ! Very exciting news ! 👏

Hej hej!🇸🇪 Happy to share that I’ve started a new postdoc with @_michael_scholl on the #REAL-AD study! Grateful for joining his incredible team together with @EllenSingletonn and contributing to this purposeful research 🧠✨ #endalz

Exciting discussions underway at the #YouCliN Retreat in Thun! 🌟 Key topics on the agenda: fostering interdisciplinarity in clinical neurosciences, advancing the Common Trunk program, and championing Brain Health. 🧠 Stay tuned for insights and updates!

Great to see our review on intracerebral haemorrhage now published in @NatRevNeurol ! Great collaboration with @SimonFaHo @mbgoeldlin #YangDu #WilmarJolink #CatharinaKlijn and #DavidWerring! @UCLStrokeRes @StrokeBern @MASStroke @ESOstroke @WorldStrokeEd nature.com/articles/s4158…

International Working Group suggests biomarker positive cognitively normal individuals should not be diagnosed as having Alzheimer disease and instead are at-risk. ja.ma/40zQ86e #CTAD24

(1/3) In which patients with intracerebral hemorrhage should advanced work-up such as digital subtraction angiography be performed? The MACRO score may help - using a few simple MRI parameters it allows to reliably assess the risk of macrovascular causes: neurology.org/doi/10.1212/WN…

This is progress. Expert IWG #Alzheimers clinicians recommend against the disease-without-symptoms 'biologically defined' @alzassociation criteria and clarify that treating pathology doesn't necessarily mean treating disease. @nvillain_alz @LonSchneiderMD jamanetwork.com/journals/jaman…

We still are overly pessimistic when assessing prognosis after #ICH In the INTERACT-3 trial Of over 6000 ICH patients physicians (75% neurosurgeons) were very accurate in Identifying who was going to die… …But massively underestimated the proportion of pts who went on to have a good recovery at six months. Surprised? #curingcoma pubmed.ncbi.nlm.nih.gov/39433033/

🚨Just published in @ESOstroke: Antithrombotic drugs for carotid artery dissection: Updated systematic review🚨 Weak evidence for #antiplatelets as standard for #carotidarterydissection. Treatment individualization is warranted! Full article here: journals.sagepub.com/doi/10.1177/23…

Register now for the @CASBrainHealth ⏳ 14 days left to register 🧠 worldwide first study programme about #BrainHealth 💻 100% Online, offered by the @unibern 🎓 15 ECTS, 4 Modules, 1 Year @EANeurology @BrainHealth_org @Euro_Psychiatry @inselgruppe @SFCNSyouclin

🧠🩸 Probable Cerebral Amyloid Angiopathy Superficial bleeding combos per Boston criteria v2.0 #NeuroTwitter #stroke #Neurology #neuropath #stroke #dementia #Alzheimers #biomarker #brain #MedStudentTwitter #AmyloidAngiopathy #CAA #cSVD #Neurosurgery #RadEd