mBio

Diatoms are responsible for almost a quarter of global primary production. How do they interact with bacteria? First, bacteria swim and secrete exudates that induce diatom death. They then aggregate around diatom debris. Learn more in #mBio: asm.social/2SB

Episode 2 of mBio's Editors in Conversation podcast is live! Hear about the aerobiome and an mBio study comparing airborne microbes over a subalpine forest vs. a grassland in Colorado. Discover how bacteria and fungi ride the wind. asm.org/podcasts/edito…

This #mBio study reveals how #redox processes in the endoplasmic reticulum regulate protein folding & calcium signaling in #Toxoplasma gondii, uncovering a mechanism essential for parasite growth & identifying potential targets for therapeutic intervention doi.org/10.1128/mbio.0…

Using a rodent malaria model, this #mBio study shows that IFN-γ signaling in T cells plays an important role in malaria-associated lung pathology. Disruption of IFN-γ signaling in T cells leads to reduced parasite load in the lungs & attenuated pathology. asm.social/2RJ

New #mBio mGem provides a novel insight that the proteins involved in #heterochromatin and cell cycle interact & regulate each other. Deregulation of these proteins causes cancer & better stress response. It may also play a role in evolution. doi.org/10.1128/mbio.0… #epigenetics

New in #mBio: a brief historical perspective on #AMR in India. The introduction of #antimicrobials in India coincided with Indian independence, when the country was dealing with disease burden that could have fueled the adoption of #antibiotics routinely. doi.org/10.1128/mbio.0…

Very proud to announce that #mBio Editors Yiping W. Han (@YipingHan1), Deborah M. Hinton, and Petra Levin and Senior Editor Michael T. Laub (@michael_laub8) have been elected as Fellows of AAAS! We are honored to have such accomplished scientists on our Board.

#mBio & 3 other ASM journals announce an open call for volunteer editors. If you're a scientist committed to advancing top-tier microbiology & fair, rigorous peer review, join the mBio Board! Apply by April 24. Details on the process & qualifications at journals.asm.org/editor-open-ca…

How do Gram-negative bacteria evade BamA-targeting antibiotics? Envelope stress (BaeSR) activates BamK, a BamA paralog, restoring outer membrane protein folding and growth in #Klebsiella. This #mBio study offers new insights for #antibiotic design. doi.org/10.1128/mbio.0…

In this #mBio mGem, Ciemniecki et al. introduce the term "facilitated fermentation," a newly recognized way bacteria make energy. It explains how microbes grow when classic fermentation or respiration doesn’t fit, with implications for nature and disease. doi.org/10.1128/mbio.0…

How do viruses spread beyond the first infected cells? This #mBio minireview examines how soluble viral “toxins” disrupt endothelial/epithelial barriers, driving vascular leak, tissue tropism, and severe disease. doi.org/10.1128/mbio.0… #virology #pathogenesis

With #cryptococcosis causing >150,000 deaths each year, this #mBio mGem summarizes progress in #polysaccharide and capsule-based vaccines for #Cryptococcus neoformans, from early filtrates to modern conjugate and synthetic designs. doi.org/10.1128/mbio.0… @ACasadevall1

While bacteria in nature experience flow, laboratory conditions typically omit flow. Using microfluidic technology, scientists discovered that flow sustains growth at glucose concentrations 1,000 times lower than traditionally observed. Read more in #mBio: asm.social/2QE

Candida auris is a fast‑spreading, drug‑resistant fungus. This #mBio #mGem offers insights into its unique adhesins to reveal how it clings to skin, pointing to potential vaccine & therapeutic targets to stop colonization, invasive infections, & outbreaks. doi.org/10.1128/mbio.0…

How bacteria and fungi "talk": this #mBio minireview unpacks quorum‑sensing signals that shape cross‑kingdom teamwork, competition, biofilms, and synthetic biology, offering a roadmap to engineer microbial communities. doi.org/10.1128/mbio.0…

New #mGem: Horses for courses in mapping bacterial small RNA interaction networks. Powerful RNA‑ligation sequencing methods now map bacterial #sRNA interaction networks in vivo, revealing how small RNAs coordinate big regulatory decisions. doi.org/10.1128/mbio.0… #mBio #genomics

Microbe vs. microbe: a DNA‑releasing showdown. New #mBio study finds that #Streptococcus mitis uses targeted #bacteriocins to burst S. pneumoniae cells, releasing DNA and boosting gene exchange, revealing a surprising mechanism shaping bacterial evolution. doi.org/10.1128/mbio.0…

New #mBio #mGem Perspective: opening HIV-1 Env with CD4-mimetic compounds and boosting NK cell functions could help expose and eliminate hidden viral reservoirs, advancing strategies toward an #HIV cure. doi.org/10.1128/mbio.0… #virology #antibody #immunology

Immunity isn't just about killing microbes; coexistence with infectious agents also requires tolerance. Vidal et al. review disease, LPS, & immunological tolerance in the gut & discuss how modern lifestyles may undermine these co-evolved defense programs. doi.org/10.1128/mbio.0…

In #mBio: a tightly regulated CRISPRi system to study essential gene perturbations in P. aeruginosa, supporting the generation of pooled mutant libraries and paving the way for future genome-wide, systematic assessment of individual gene vulnerabilities. asm.social/2PH