mBio

Adjunct #immunotherapy shows promise in deadly mold infections. New #mBio study finds anti–PD-1 + IFN-γ with #antifungals improved survival in severe cases, supporting immune-restoring strategies in invasive mold diseases. doi.org/10.1128/mbio.0…

First publication from the lab. It demonstrates how Lipid Droplets and Extracellular Vesicle interplay helps in egress of Japanese Encephalitis Virus. journals.asm.org/doi/10.1128/mb… @csir_iicb @HRDG_CSIR @DBTIndia

🔬 How do we unlock the mysteries of the microbial universe? The Spring 2026 issue of Microcosm explores how curiosity-driven, fundamental research reveals the “why” and “how” of microbial life, enabling advances that address real-world challenges.🔗 asm.social/2WH

New #mBio study finds that #Chlamydia trachomatis effector CT181 binds Mcl-1 to keep #neutrophils alive--boosting bacterial survival, #inflammation, & persistence. A new immune evasion strategy with #pathogenesis implications. doi.org/10.1128/mbio.0…

Disruption of the interaction between the phosphatase NimT & cyclin-dependent kinase NimX in A. fumigatus can be achieved with an inhibitor that arrests the fungal duplication cycle, highlighting mitotic regulators as antifungal drug targets. #mBio: asm.social/2Wj

Label-free #microscopy, real-time insights. Label-free analysis of biofilms (LFAB) enables high-throughput tracking of #biofilm growth and uncovers new genetic drivers in #Streptococcus pneumoniae. A powerful tool for biofilm biology. doi.org/10.1128/mbio.0… #mBio #genetics

Group B Streptococcus (GBS), the leading cause of neonatal sepsis and meningitis, is associated with the mucin-degrading intestinal commensal Akkermansia muciniphila, a newly identified colonizer of the vaginal tract. #mBio: asm.social/2VY

Showing the data is the first rule of figures. So it's good news that biologists increasingly show the data in their figures--but there is still room for improvement. doi.org/10.1128/mbio.0… #mBio

How can scientific societies drive impact? A new portfolio model from the American Academy of Microbiology positions microbial sciences as a driver of real-world solutions, policy, and innovation. doi.org/10.1128/mbio.0… #mBio #climatechange #microbiology

#MicrobiologyMonday: S. aureus has been observed within nanoscale channels in bone that are 2–3 times smaller than its own diameter. How does it get there? Fluid pressures in the body may help transport the bacteria into bone. Learn more in #mBio: asm.social/2UX

SARS-CoV-2 without nsp14 proofreading? It persists, but with reduced replication, fidelity, fitness, and pathogenicity. New insights into #antiviral targets and virus–host interactions. doi.org/10.1128/mbio.0… @timothysheahan #mBio #coronavirus #pathogenesis

Mitochondria do more than power cells; they shape antiviral immunity. This new #mBio mGem offers insights into metabolic rewiring during infection. doi.org/10.1128/mbio.0… #immunology #virology #mitochondria #immunometabolism

Obesity is typically associated with more severe disease during #influenza & #SARS-CoV2 infections, amongst other respiratory pathogens. Surprisingly, this #mBio study finds diet-induced obese mice actually fare better during #RSV infection. @SSCLabQuips doi.org/10.1128/mbio.0…

The Guild Model of Cystic Fibrosis Airway Microbial Ecology organizes CF airway microbes into four Guilds based on ecological function: Brewers, Drunkards, Putrifiers, and Nihilists. This model offers a transferable framework for microbial disease ecology. doi.org/10.1128/mbio.0…

New #mBio podcast episode! Meet bacteriophage JS1, a contractile phage with a rare twist: a curved, flexible tail that may help it navigate the “canyons and valleys” of the bacterial cell wall. Hosted by @whiteleylab; guests Sabrina Suhani & Trevor Lithgow asm.org/podcasts/edito…

🏅 #mBio & @journal_mlife jointly present the Emerging Leader in Microbiology Award, a new initiative designed to recognize & support early career researchers whose work is shaping the future of microbial science. 🖥️ Apply or nominate by July 31. asm.social/2UZ

#HIV and #Alzheimer’s pathways intersect: this new #mBio minireview explores how amyloid precursor protein (APP) shapes #microglial antiviral defenses and contributes to neurotoxicity in HIV-associated neurocognitive disorders. doi.org/10.1128/mbio.0…

A beneficial virus boosts a fungal pathogen. RsEV-IM #endornavirus supercharges Rhizoctonia solani growth, virulence, and competition. doi.org/10.1128/mbio.0… #mycovirus #mBio

#Brucella manipulates host G protein-cAMP signaling to enhance intracellular growth. Disrupting Gαs-driven signaling or enhancing opposing pathways limits intracellular replication, revealing host signaling networks as potential therapeutic targets. doi.org/10.1128/mbio.0… #mBio

🚨A random solution to a growing fungal threat🚨 Our work on random peptide mixtures reveals potent antifungal activity against multidrug-resistant pathogens like C. auris, with low resistance potential and strong biofilm activity. Now out in mBio! journals.asm.org/doi/10.1128/mb… ⬇️