mBio

In this #mBio mGem, Ciemniecki et al. introduce the term "facilitated fermentation," a newly recognized way bacteria make energy. It explains how microbes grow when classic fermentation or respiration doesn’t fit, with implications for nature and disease. doi.org/10.1128/mbio.0…

How do viruses spread beyond the first infected cells? This #mBio minireview examines how soluble viral “toxins” disrupt endothelial/epithelial barriers, driving vascular leak, tissue tropism, and severe disease. doi.org/10.1128/mbio.0… #virology #pathogenesis

With #cryptococcosis causing >150,000 deaths each year, this #mBio mGem summarizes progress in #polysaccharide and capsule-based vaccines for #Cryptococcus neoformans, from early filtrates to modern conjugate and synthetic designs. doi.org/10.1128/mbio.0… @ACasadevall1

While bacteria in nature experience flow, laboratory conditions typically omit flow. Using microfluidic technology, scientists discovered that flow sustains growth at glucose concentrations 1,000 times lower than traditionally observed. Read more in #mBio: asm.social/2QE

Candida auris is a fast‑spreading, drug‑resistant fungus. This #mBio #mGem offers insights into its unique adhesins to reveal how it clings to skin, pointing to potential vaccine & therapeutic targets to stop colonization, invasive infections, & outbreaks. doi.org/10.1128/mbio.0…

How bacteria and fungi "talk": this #mBio minireview unpacks quorum‑sensing signals that shape cross‑kingdom teamwork, competition, biofilms, and synthetic biology, offering a roadmap to engineer microbial communities. doi.org/10.1128/mbio.0…

New #mGem: Horses for courses in mapping bacterial small RNA interaction networks. Powerful RNA‑ligation sequencing methods now map bacterial #sRNA interaction networks in vivo, revealing how small RNAs coordinate big regulatory decisions. doi.org/10.1128/mbio.0… #mBio #genomics

Microbe vs. microbe: a DNA‑releasing showdown. New #mBio study finds that #Streptococcus mitis uses targeted #bacteriocins to burst S. pneumoniae cells, releasing DNA and boosting gene exchange, revealing a surprising mechanism shaping bacterial evolution. doi.org/10.1128/mbio.0…

New #mBio #mGem Perspective: opening HIV-1 Env with CD4-mimetic compounds and boosting NK cell functions could help expose and eliminate hidden viral reservoirs, advancing strategies toward an #HIV cure. doi.org/10.1128/mbio.0… #virology #antibody #immunology

Immunity isn't just about killing microbes; coexistence with infectious agents also requires tolerance. Vidal et al. review disease, LPS, & immunological tolerance in the gut & discuss how modern lifestyles may undermine these co-evolved defense programs. doi.org/10.1128/mbio.0…

In #mBio: a tightly regulated CRISPRi system to study essential gene perturbations in P. aeruginosa, supporting the generation of pooled mutant libraries and paving the way for future genome-wide, systematic assessment of individual gene vulnerabilities. asm.social/2PH

Fiber does more than feed your gut. It helps protect good microbes from oxygen stress and keeps harmful ones in check. New research in #mBio shows how high‑fiber diets promote a balanced and resilient #microbiome. doi.org/10.1128/mbio.0… #fermentation #anaerobe

mBio Editor in Chief, Marvin Whiteley hosts the first mBio edition of Editors in Conversation: How climate change may be reshaping the fungal kingdom, potentially eroding the thermal barrier that has historically protected humans from most fungal pathogens asm.social/2PS

"Low pathogenicity" avian influenzas can sometimes be deadly to poultry. This #mBio study shows how 2 amino acid differences in the viral neuraminidase & hemagglutinin work together to turn a relatively harmless flu into a more dangerous virus for chickens doi.org/10.1128/mbio.0…

Zhao et al. describe how the critically important G521 residue at the center of transmembrane segment 1 decides which compounds can enter & inhibit or are subject to export by the major #Candida albicans multidrug efflux pump, Cdr1. #mBio #antifungal #AMR doi.org/10.1128/mbio.0…

New #mBio mGem: clinical #microbiome therapeutics offer a new lens for agricultural bioproduct design. Coordinated approaches across sectors could redefine how microbial bioproducts are developed and deployed. doi.org/10.1128/mbio.0…

IgA has major effects on Cryptococcus neoformans (Cn) growth, morphology & protein synthesis, lending plausibility to the hypothesis that reported reductions in IgA levels in HIV-associated cryptococcal meningitis may influence Cn pathogenesis. #mBio: asm.social/2OV

ASM is seeking nominations for the ASMDL Roster, a diverse group of scientists with outstanding speaking ability who deliver lectures and participate in career development and mentoring activities at ASM Branch meetings. Nominate a lecturer by March 2! asm.social/2OU

Early registration for #ASMicrobe 2026 is now open. Register by March 18 and save up to $605. Secure your spot in the inaugural year of ASM Microbe’s new meeting experience: asm.social/2OG

🎉Congratulations to #mBio Editors Jorge Vidal (@JorgeEVidal1), Jacob Yount (@YountLabOSU), and Birgit Scharf (of @VT_Biology) and Senior Editor Tom Coenye (of @LPM_UGent) on their election to the American Academy of Microbiology! 👏 asm.social/2OC