Magali Noval Rivas

Our latest Review on the role of platelets in Kawasaki disease vasculitis. Platelets are mediators of inflammation in Kawasaki disease with @magalinoval and @bernardo647 @SmidtHeart @CedarsSinaiMed @GuerinChildrens nature.com/articles/s4158…

Our fabulous postdoc Dr. Thacyana T. Carvalho @magalinoval lab. presenting her work on IL33 and murine model of #Kawasaki disease vasculitis #VascularDiscovery24 in Chicago. @AHAScience @atvbahajournals @SmidtHeart @GuerinChildrens @CedarsSinaiMed

We are excited to announce this year's keynote speaker for ImmunologyLA Pamela Bjorkman @bjorkmanlab. Please save the date. Abstract submission and registration will open at the beginning of April.

⁦@atvbahajournals⁩ “Inhibition of IL-1 signaling, but not TNF neutralization, improves myocardial dysfunction, and arrhythmias in LCWE-induced murine model of Kawasaki disease vasculitis”. ahajournals.org/doi/pdf/10.116…

Our own postdoc Thacyana Carvalho received the AAI Young Investigator Award , Dec 1 st at the 21st Annual UC Irvine Institute for Immunology Symposium. Among top five best posters👏👏. ⁦@CedarsSinaiMed⁩ ⁦@SmidtHeart⁩ ⁦@GuerinChildrens⁩

Dec 1st. 21st Annual UC Irvine Institute for Immunology Fair. Dr. Magali Noval Rivas with three of our postdocs who each presented abstracts in the annual symposium. ⁦@CedarsSinaiMed⁩ ⁦@SmidtHeart⁩ ⁦@GuerinChildrens⁩

"I want my patients and their families to know that when they come to see me, or any of our expert team members, that they'll receive the best individualized care here for their children. We will always treat them very special and we will always be available to them." - @ArditiMd

@bernardo647 Congratulations Bernardo!

@ArditiMd @ImmunologyAAI @GuerinChildrens @CedarsSinaiMed Congrats @carvalho_thacy ! #AAI2023

Congrats! Dr. Thacyana Carvalho in Magali Noval Rivas lab presenting her work “IL-33 and Kawasaki Disease vasculitis”(oral pr &poster) for 2023 AAI Trainee Abstract &Travel Award! ⁦⁦@ImmunologyAAI⁩ #immunology2023. @GuerinChildrens ⁦⁦⁦⁦⁦@CedarsSinaiMed⁩

Amazing talks this morning at the “Cytokine and Chemokine Control of Cellular Immunity” session! #AAI2023

Very excited to be in Washington, DC attending for the first time the @ImmunologyAAI #immunology2023 meeting. Come watch my talk tomorrow morning (Room 101) or come by my poster on Saturday afternoon (P333) to hear about the role of IL-33 in a mouse model of Kawasaki Disease.

We are looking for an NIH- funded postdoc researcher in our immuno biology/ vascular biology labs @CedarsSinai @magalinoval to investigate murine models of Kawasaki D. vasculitis, AAA and atherosclerosis, role of gut microbiome, NLRP3 inflamm & IL-1b. jobs.cedars-sinai.edu/job/los-angele…

Our Review pre-print is online..“Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: common inflammatory pathways of two distinct diseases”- Rheumatic Disease Clinics ⁦@yoncabulutmd⁩ ⁦@GuerinChildrens⁩ ⁦@CedarsSinaiMed⁩ rheumatic.theclinics.com/article/S0889-…

11/11 Finally, recent scientific advances on Long COVID led us to hypothesize that repeated exposure to the "SAg-like motif" may lead to autoimmunity & neurotoxins may lead to the neurological findings in PACS. These are the 2 key concepts of our new Frontiers immunology paper.

10/11 all this work was highlighted and discussed by @rkhamsi in an article at "The Atlantic". You can read it on this link: theatlantic.com/science/archiv…

9/11 We next showed that an anti-SEB monoclonal antibody can potentially bind the “SAg-like motif" and block SARS-CoV-2 cellular infection in vitro. in BioRxiv (Nov 2020) and published in Structure in 2021 sciencedirect.com/science/articl…

8/11 Using proteomics, RNA-sequencing, autoantibody arrays and B cell receptor sequencing, we then identified strong autoimmune signatures and pathogenic pathways associated with MIS-C. This work was published in JCI. jci.org/articles/view/…

🧵1/11 Our newest paper on the "Superantigen (SAg) hypothesis" leading to autoimmunity and neurotoxin-like motifs in post-COVID syndromes, including MIS-C and Long Covid, is now online! @ArditiMd @IvetBahar @CedarsSinai #LongCovid #MISC #SARSCoV2 frontiersin.org/articles/10.33…

7/11 Which was then published in JCI, and we also showed HLA class I–associated expansion of TRBV11-2 T cells in MIS-C patients. jci.org/articles/view/…

6/11 In Nov 2020, we deposited in bioRxiv our 1st report showing TCR repertoire skewing in MIS-C patients & expansion of TRBV11-2 T cells, which we predicted by computational studies to interact with the SARS-CoV-2 “SAg-like motif”. biorxiv.org/content/10.110…

5/11 This hypothesis and our original findings were the basis of an article published in National Geographic October 2020. You can read it here: nationalgeographic.com/science/articl…