Behnas Malek F.Z

@is_maha44 Merci ، Eid Mubarak à vous aussi . Que cette journée soit remplie de joie et de bénédictions pour vous et vos proches inchallah ❤️

le plus simple à répondre pour « aid mabrouk » c quoi ?

🔬 Molecular Pathology of Adipocytic Tumors — High-Yield Map Morphology 🧫 + genetics 🧬 + behavior ⚠️ in one glance. Lipoma (HMGA2) → ALT/WDL (MDM2/CDK4) → DDL (JUN). 🎯 Rapid revision for FRCPath | NEET SS #Pathology #MolecularPathology #Liposarcoma #Lipoma #FRCPath #NEETSS

Intestinal spirochetosis, caused by Brachyspira spp, cross reacts with the T. pallidum immunohistochemical stain. Pettit C, et al. Highlighting a Potential Pitfall: Positive Treponema pallidum Immunohistochemical Stain in a Patient Without Syphilis. PMID: 31389806.

#GUpath prostate biopsy for elevated PSA at first blush foamy gland pattern prostatic adenocarcinoma comes to mind... but other DDx include Cowper gland (Dx here) or mucinous metaplasia ⏬cont'd

Adrenalectomy 🧌 🔬 #Endocrine #Pathology #PathX #PathTwirltter

True goblet cells contain acid mucin,show a triangular nucleus, and stain Alcian blue positive🔵 Pseudo-goblet cells are actually gastric foveolar cells with neutral mucin, showing PAS magenta staining🟣 #Pathology #Histopathology #PathologyMCQ #GIPathology #BarrettEsophagus

What are the "must know" features of seminoma? 🧐 Take a look at our recently updated @Pathoutlines piece here: pathologyoutlines.com/topic/testisse… #GUPath

#backtobasics Pilomatrixoma 🔬 ✔️Benign skin adnexal tumor ✔️basaloid proliferation resembling the hair matrix cells, which matures into structureless eosinophilic cells lacking nuclei called shadow/ghost cells ✔️Frequently there are areas of calcification #xpath #dermpath

Verrucous carcinoma of the penis 🔬 Broad-based, exophytic lesion with pushing borders. Note the bulbous rete ridges and keratin-filled sinuses, classic for this low-grade variant. Despite its bland cytology, local invasion can be extensive. Early recognition is key. #GUPath

Liposarcoma: types & salient features (Basic facts for residents)

PseudoAngiomatous Stromal Hyperplasia ( PASH) ✔️Complex interanastomosing spaces in collagenous stroma resembling blood vessels ✔️Some of these spaces have spindle shaped myofibroblasts at their margins simulating endothelial cells ✔️- for vascular markers except CD34

Malakoplakia of bladder: Sheets of histiocytes (von Hansemann cells) packed with granular cytoplasm and the pathognomonic Michaelis–Gutmann bodies—round, targetoid inclusions reflecting defective phagolysosomal activity and chronic E. coli infection. #Pathology #UroPath #MedEd

Large Nested Urothelial Carcinoma on H&E 🔬 Deceptively bland cytology with expansile, well-circumscribed nests infiltrating the lamina propria—an architectural wolf in sheep’s clothing. Recognition is critical to avoid underdiagnosis of this aggressive variant. #Pathology

Cystadenoma (Warthin Tumor) Sclerosing Polycystic Adenoma (SPA) Basal Cell Adenoma (BCA) Salivary gland pathology #pathology

🔬 Kimura Disease vs Epithelioid Hemangioma (ALHE) 🟣 Lymphoid dominance + IgE ↑ + Asian male → Kimura 🔴 Plump “hobnail” endothelial cells + vascular proliferation → ALHE #DermPath #HeadNeckPathology #VascularTumors #InflammatoryLesions #PathologyResidents #NEETSS

Molecular Pathology of Ependymoma — simplified & exam-ready 🧠✨ From ZFTA & YAP fusions to Posterior Fossa A/B and spinal MYCN tumors, molecular classification now drives prognosis, grading, and reporting. #Ependymoma #Neuropathology #MolecularPathology #WHO2021 #PathologyMCQs

Pleomorphic adenoma “canalicular adenoma–like” / “monomorphic” variant 🔬 ✔️Monotonous, monophasic appearanc ✔️Predominantly trabecular architecture ✔️May contain focal areas of classic PA IHC: CK7+ HMGA2+ S100+ SOX10+ p40- SMA- 🧬 Molecular : HMGA2::WIF1 fusion transcript

🔬Globular amyloid - gastric biopsy ✔️Amyloid doesn’t always appear as diffuse sheets ✔️“Globular” pattern = round, well-circumscribed eosinophilic deposits in lamina propia ✔️Congo red + → apple-green birefringence ✔️always confirm and type ( AL amyloidosis vs AA amyloidosis)

Elderly man, foot mass. Previous superficial shave biopsy called SCCIS. This is the excision. #dermpath

🔬 Pseudoangiomatous Stromal Hyperplasia vs Diabetic Mastopathy Rubbery & circumscribed → PASH Slit-like spaces, CD31 negative 🧪 Hard & ill-defined in diabetic → DMP Keloid fibrosis + CD20⁺ B-cells 🧠 #Pathology #BreastPathology #Histopathology #IHC #DifferentialDiagnosis