Manuel Perez Escribano

237 posts

Manuel Perez Escribano banner
Manuel Perez Escribano

Manuel Perez Escribano

@manuelperezesc

Theoretical and Computational (@KU_Leuven) Chemist (@UMU).

Valencia, Spain Katılım Haziran 2022
418 Takip Edilen274 Takipçiler
Manuel Perez Escribano retweetledi
Aakash Gupta
Aakash Gupta@aakashgupta·
This isn’t a random scientist who got lucky. Mariano Barbacid discovered the first human oncogene in 1982. He isolated H-RAS from bladder cancer cells and proved a single point mutation could trigger cancer. That finding launched the entire field of molecular oncology. KRAS mutations cause 90% of pancreatic cancers. For 43 years, oncologists called KRAS “undruggable” because the protein had no obvious binding pocket. Barbacid spent the last decade using genetically engineered mice to systematically test every node in the KRAS signaling pathway, looking for combinations that would work without killing the patient. The triple therapy blocks KRAS three ways at once: the main growth signal, the escape routes through EGFR and HER2, and the stress-response backup through STAT3. Cut the engine, seal the exits, disable the emergency system. Tumors vanished in mice and didn’t return for 200+ days after treatment stopped. Pancreatic cancer has a 13% five-year survival rate. 8% for the ductal adenocarcinoma type this therapy targets. Most patients live one year after diagnosis. The catch: this is preclinical. Human trials are 3+ years away. One of the drugs, RMC-6236, might get approved this year, but the full triple combination has regulatory hurdles. Still. The man who discovered human oncogenes in 1982 may have just figured out how to eliminate the cancer those genes cause. That’s a 43-year arc from first principles to potential cure. Science rarely works this clean.
All day Astronomy@forallcurious

BREAKING🚨: This is Mariano Barbacid, the scientist who may have discovered the cure for pancreatic cancer.

English
186
15.3K
79.6K
2.1M
Manuel Perez Escribano retweetledi
ICMol
ICMol@ICMol_UV·
📢ICMol researchers among the world’s top 2% most cited scientists 📷 Several researchers from the Institute of Molecular Science (ICMol) at the University of Valencia are listed among the top 2% most cited scientists worldwide, according to the 2025 update of Stanford University’s World Ranking of Scientists. The list includes: Henk Bolink; Joaquín Calbo, Eugenio Coronado Miralles; Ferrando-Soria, Jesùs; Gaspar, Ana Belén; Carlos Martí-Gastaldo; Mínguez Espallargas, G.; Pardo, Emilio; Real, José Antonio.
ICMol tweet media
English
0
2
24
1.2K
Manuel Perez Escribano retweetledi
ICMol
ICMol@ICMol_UV·
📢 This month we already have 3 #ICMolTalks scheduled, You are all invited! Check out these talks and all our upcoming events in our agenda 👉icmol.es/agenda.php?men…
ICMol tweet mediaICMol tweet mediaICMol tweet media
English
0
3
10
699
Manuel Perez Escribano retweetledi
Daniel Escudero Masa
Daniel Escudero Masa@Dr_Escudero·
A very productive week! Interested in a quantum chemical descriptor to pre-screen INVEST TADF properties? Check Youssef's preprint! chemrxiv.org/engage/chemrxi…
English
3
3
17
817
Manuel Perez Escribano retweetledi
QuimComp
QuimComp@CompQuim·
📢Job offer: PhD position (FPI) at @ICMol_UV (Profs. Profs. Juan Aragó and Joaquín Calbo). Project: "Computational Modelling of Complex Systems for Energy and Sustainability". More information and application: shorturl.at/WwTpi
QuimComp tweet media
English
0
4
5
627
Manuel Perez Escribano retweetledi
TheoChem_EHU
TheoChem_EHU@TheoChem_EHU·
Group picture on the last day of the 25th Anniversary Workshop of the TCCM Master #TCCM25th ⚗️💻 Congratulations to the organisers and big thanks to all the participants for coming to Donostia-San Sebastián 👏👏👏👏 @uik_eus @upvehu @ehu_kimika @DIPCehu @RSEQUIMICA
TheoChem_EHU tweet media
English
0
5
20
1.1K
Manuel Perez Escribano
Manuel Perez Escribano@manuelperezesc·
Last week I was very lucky that I could attend #WATOC2025. I contributed with a poster about our work on the charge transport properties of hole transporting materials at @ICMol_UV ☀️⚡️
Manuel Perez Escribano tweet mediaManuel Perez Escribano tweet mediaManuel Perez Escribano tweet media
English
0
1
23
667
Manuel Perez Escribano retweetledi
José Ruiz López
José Ruiz López@jruizum·
Great success at the XL Biennial Meeting of the Spanish Royal Society of Chemistry (RSEQ) in Bilbao! Preparations are already underway for the XLI Biennial Meeting in Murcia, 2027!🔬 #RSEQ #Chemistry
XL Reunión Bienal de la RSEQ - Bilbao, 2025@BienalRSEQ2025

🎉 Closing Ceremony – #BQB2025 After 4 intense but inspiring days, it’s time to wrap up this incredible edition of #BQB2025! Thank you to all the participants, speakers, organizers and sponsors who made it unforgettable. See you at the next one! 👋 @RSEQUIMICA @BEC_Bilbao

English
2
5
33
1.9K
Manuel Perez Escribano retweetledi
QCEXVAL
QCEXVAL@qcexval·
We are hiring!! Contact ASAP
QCEXVAL tweet media
English
1
6
6
597
Manuel Perez Escribano retweetledi
QCEXVAL
QCEXVAL@qcexval·
😃😃😃@A_Frances_chem from @qcexval @ICMol_UV has been awarded by the 2025 Young Investigator Prize from the @EurSocPhotobiol, Congratulations!!!!
European Society for Photobiology@EurSocPhotobiol

🥁 Drum roll......the 2025 Young Investigator Awardees have been selected! Congratulations to Nicoletta Liguori @nikinikki87 and Antonio Francés-Monerris @A_Frances_chem 🎉 They will deliver the Young Investigator Award Lectureship at the #ESPCongress2025 See you all there!

English
0
2
6
518
Manuel Perez Escribano retweetledi
ICMol
ICMol@ICMol_UV·
ICMol is accredited for the third consecutive time as a María de Maeztu Unit of Excellence in the provisional resolution of the AEI. We’re proud of the incredible work and dedication of the 300+ people who make up our institute. Together, we keep pushing the frontiers of molecular science! ℹ️More Information: icmol.es/new.php?pas=10… #ICMol #Nanoscience #WeAreICMol ph:UB
ICMol tweet mediaICMol tweet media
English
1
12
48
4K
Manuel Perez Escribano retweetledi
Rocio Semino
Rocio Semino@RS_Chemist·
Felicitaciones Dra. María Esteve Rochina! Muy buena la defensa y un gran placer compartir con Enrique Ortí, Joaquín Calbo y los otros jurados en la preciosa Valencia. Gracias por la invitación y la hospitalidad! @MEsteveRochina @ICMol_UV @UV_EG
Rocio Semino tweet mediaRocio Semino tweet media
Español
0
3
13
794
Manuel Perez Escribano retweetledi
Daniel Escudero Masa
Daniel Escudero Masa@Dr_Escudero·
📢📢Interested in transition metal complexes' photophysics? PhD opening at @LudoTroian 's lab (UCL, Louvain-la-Neuve) and at my lab (KU Leuven). Please RT
Daniel Escudero Masa tweet media
English
3
37
71
15.8K
Manuel Perez Escribano retweetledi
QCEXVAL
QCEXVAL@qcexval·
Two new doctors this month at the Theoretical Research Unit @ICMol_UV, Miriam from @qcexval and María from MolMatTC - @UV_EG
QCEXVAL tweet mediaQCEXVAL tweet media
English
0
5
18
776
Manuel Perez Escribano retweetledi
ICMol
ICMol@ICMol_UV·
🎉 Congratulations to Miriam Navarrete Miguel from the QCEXVAL group on successfully defending her PhD thesis: “Photophysical and photochemical mechanisms of DNA damage and repair” 🔬✨ Supervised by Dr. Daniel Roca Sanjuán (ICMol-UV) & Dr. Virginie Lhiaubet-Vallet (CSIC-UPV). #WeAreICMol #PhDDefense 🎓👏
ICMol tweet media
English
0
5
50
1.9K
Manuel Perez Escribano retweetledi
Henar Mateo
Henar Mateo@mateo_henar·
Aunque a veces se olvide que existimos, hay muchas mujeres haciendo ciencia y como, nunca está de más recordarlo, estoy organizando una exposición artística para destacar la investigación científica de algunas de ellas Así que si estás por Madrid no dudes en pasarte a verla!
Henar Mateo tweet media
Español
1
10
13
1.7K