Marc Landers

Cannabis does not CAUSE psychosis The Lancet "Most reports examining associations between cannabis and psychosis have been unable to adjust for confounding that arises from correlated genetic and environmental individual differences."... "By not acknowledging the alternative, compelling and plausible mechanisms,3 Di Forti and colleagues' conclusion regarding the harmful effect of high-potency cannabis use on mental health is likely to be overestimated." thelancet.com/journals/lanps… Psychcentral “The results of the current study suggest that having an increased familial morbid risk for schizophrenia may be the underlying basis for schizophrenia in cannabis users and not cannabis use by itself,” note the researchers." psychcentral.com/news/2013/12/1… National Institute of Health "Conclusions: Substance-induced psychotic disorder appears to result from substantial drug exposure in individuals at high familial risk for substance abuse and moderately elevated familial risk for psychosis. Familial risk for psychosis, but not substance abuse, predicts progression from substance-induced psychosis to schizophrenia. Schizophrenia following substance-induced psychosis is likely a drug-precipitated disorder in highly vulnerable individuals, not a syndrome predominantly caused by drug exposure." pubmed.ncbi.nlm.nih.gov/31055966/ Psychology Today "Today, medical science lacks sufficient data to make a definitive claim regarding whether smoking marijuana induces psychosis. If you’re young, consume a lot of high-dose marijuana products every day, and possess a genetic predisposition to psychosis, then yes, you are at risk." psychologytoday.com/gb/blog/your-b… Very Well Mind “Research suggests that people who have a co-occurring mental health disorder along with a substance use disorder are at a higher risk of developing psychosis associated with the substance or medication use.1 This may suggest that substances such as marijuana may trigger the onset of a psychotic episode in people who have a predisposed risk for psychosis.” verywellmind.com/can-marijuana-… UK Advisory Council on the Misuse of Drugs “It is evident that the majority of young cannabis users do not develop psychotic illnesses. Those who do so must have one or more predisposing factors.” [Those factors being genetic and environmental.] “Anxiety and depression 12.10 The Council remains unconvinced that there is a causal relationship between the use of cannabis and the development of any affective disorder (Sections 8.12 and 8.13).” assets.publishing.service.gov.uk/government/upl… “Researchers have associated cannabis use with risk for psychosis, cognitive impairment, and traffic accident. However, this review shows that the association between moderate cannabis use and psychosis is no stronger, and often considerably weaker, than the corresponding association for moderate tobacco use. The same holds for associations with cognitive impairment. For the risk of traffic accident, the review confirms that the risk from alcohol use is substantially stronger than the risk from cannabis use,…” journals.sagepub.com/doi/full/10.11… From the National Institute of Health “Predictors of cannabis-related mental and behavioral disorders include prior substance use disorders, other mental disorders, age, diabetes, and chronic obstructive pulmonary disease.” pubmed.ncbi.nlm.nih.gov/35866679/ State Cannabis Legalization and Psychosis-Related Health Care Utilization “Findings  In this cohort study of claims data from 63 680 589 beneficiaries from 2003 to 2017, there was no statistically significant difference in the rates of psychosis-related diagnoses or prescribed antipsychotics in states with medical or recreational cannabis policies compared with states with no such policy.” jamanetwork.com/journals/jaman… “There was no significant association between any measure of cannabis use at baseline and either transition to psychosis, the persistence of symptoms, or functional outcome.” pubmed.ncbi.nlm.nih.gov/37070555/ No evidence to suggest cannabis use causes schizophrenia “Most neuroscientists accept the conclusion that the origins of schizophrenia are to be found during gestation of the fetus. In other words, schizophrenia is regarded as a neurodevelopmental disorder.” ualberta.ca/folio/2018/10/…

@GeraldAdamsIWV I'm working on it! 😎

@marclanders stay healthy feed your endocannabinoid system every day with cannabis live long - stay mellow...

We have an article coming out on this later today. Stay tuned! 😎

@TERP_THCA Nope, and we've posted dozens if not hundreds of studies on this. For example,

@marclanders The benefit never stop with this cannabinoid.

Who knew? CBD neuters deadly Listeria! Listeria monocytogenes (often just called Listeria) is a harmful bacteria that causes food poisoning. At 6 times the low dose (about 22.5 µg/mL), CBD strongly reduced the bacteria's ability to move, make toxins, stick to human gut cells (Caco-2), and invade brain cells (HBMEC). It also turned down many of Listeria's key "attack" genes (like prfA the master switch, hly for the main toxin, plcA/plcB for escape tools, actA for cell-to-cell spread, inlA/inlB for entering cells, motA/motB for movement, and iap for attachment). Link in the comments 👇 mdpi.com/1422-0067/27/6… #MedicalCannabis #CannabisResearch #BudMed

That's $2.12 BILLION taken out of the illegal market. Imagine if cannabis was Federally legal and legal in all 50 States! 😎

@alexwg Alex, what's happened to Moonshots? Haven't seen a new episode all week. You guys must be real busy. Looking forward to the next one!

@weedcoinOG What a coincidence! We have an article on this coming out later today.

New research suggests the body's endocannabinoid system could be the key to triggering self-destruction in cancer cells—and early clinical trials are showing dramatic results. Humans possess an internal network called the endocannabinoid system, which regulates vital functions from sleep to immune responses. Because active compounds in cannabis structurally mimic molecules our bodies produce naturally, they can bind to receptors on cancer cell surfaces like a key in a lock. In laboratory settings, this interaction demonstrated remarkable ability to block the cell growth cycle and starve tumors of blood supply. Most significantly, these compounds can trigger programmed cell death—essentially commanding cancer cells to commit suicide while leaving healthy tissue completely intact. This potential is moving from petri dish to patients. In a study targeting glioblastoma, an aggressive brain tumor, patients treated with cannabis-based medicine alongside chemotherapy saw an 83% survival rate after one year—nearly double the 44% seen in the placebo group. Here's the critical distinction: experts at Cancer Research UK caution that ingesting street cannabis is not a substitute for highly concentrated, clinical-grade treatments used in these trials. The dosing, purity, and delivery methods matter enormously. But the findings mark a critical step toward turning the body's own biological systems into a precision weapon against disease. Your endocannabinoid system may hold keys to fighting cancer we're only beginning to understand. Reference: Cancer Research UK (2022) "Cannabis, cannabinoids and cancer – the evidence so far"

@vizurantvis Yep! We've posted numerous studies on all these effects.

Why Cannabis Can Replace Opioids & Alcohol: The Science-Backed Switch That’s Saving Lives 💨🍃✨ ••••••••••••••••••••••••••••••••••••••••••• Tired of the opioid nightmare? 👹🔥 Medical cannabis patients report slashing opioid use by up to 64% with 97% saying they cut back or quit because cannabis handles chronic pain just as well (or better) without the addiction, deadly overdose risk, or brutal side effects. States with legal cannabis see 16% fewer opioid prescriptions and drops in daily opioid misuse. Perhaps this is why Big Pharma is panicking?? Struggling with booze? The “California Sober” movement is real for a reason. Brand-new 2025-2026 studies (Brown University lab trial + real-world surveys) prove it: • Smoking cannabis cuts alcohol intake 19-27% on the spot and kills cravings instantly. • People using cannabis drinks report halving their weekly drinks and bingeing way less. (Thank you, Gen Z‼️) • 44% of medical cannabis users naturally drink less or quit alcohol entirely. ••••••••••••••••••••••••••••••••••••••••••• Cannabis is vastly safer, non-lethal, and gives people real control without the hangover from hell or the body count of opioids/alcohol. As of 2026, 💀 toll from alcohol is 178k annually Opioid claiming 50-80k annually 💊🪦 Science says it’s time to stop demonizing a plant that’s already helping millions. Drop a 🔥🍃 if you’ve seen this switch work

Out today! Don't miss these! "CBD neuters deadly Listeria!" And an article, "Cannabis compounds may fight breast, prostate & colon cancers!" Stay tuned! 😎

@MitchGordon_ I know, but I think it's just an excuse at this point. Still, schedule 3 would give a lot of politicians cover.

@marclanders I agree but that’s what the governor personally said to me at the Indy 500 last year.

Indiana is surrounded with States that have legalised cannabis in some form. How long can Indiana hold out?

@Marginmn @AlderLaneEggs The former head of the DEA said, it's because, so many DEA agents lost their lives over the years in the war on drugs. It's baked into their dna to resit legalising any drugs. Hence, the DEA collaborated with Sabet and his SAM organisation to sabotage the Administrative Hearing.

@marclanders @AlderLaneEggs For the life of me I cannot understand why the DEA cannot occupy themselves and be content with closing down the illegal pot growers that put out tainted, pesticide-filled, untaxed and unregulated weed. It's not like there won't be illegal weed out there when they reschedule.

Yet Cannabis is a schedule 1 drug

@honeybadger7734 Let's hope we schedule 3 soon and that changes things for some of these hold out States. 😎

@marclanders Typically, states implement crazy laws like this until they’re no longer financially viable—people move to other states, buy from other states, etc., so the revenue from what was expensive to enforce isn’t really a threat to begin with.

@honeybadger7734 It's starting to lose its scare factor. We see that with 24 States legalising adult use and 40 legalising medical. Who knows, we may wind up with all 50 States ignoring the Feds and doing their own thing. We're almost there already. 😎

@marclanders It’s age old scare tactic, “you can have this but not that”.

In addition, allowing CBD with THC to be reimbursed on Medicare, means maintaining cannabis in Schedule 1, (meaning cannabis has no medical value), makes no sense. They both can't be true.

@MitchGordon_ That's what they keep saying but that hasn't stopped other States. In addition, now that Medicare is set to pay for CBD with THC, Schedule 1 makes even less sense now.

@marclanders Indiana cannot legalize or made marijuana medical under schedule 1. They need rescheduling before doing anything. The governor has said he will look to move to legalize adult use after rescheduling.

@honeybadger7734 Question is, how long can they hold out. Some Indiana, and Pennsylvania politicians claim Schedule 1 is holding them back. But with Medicare set to pay for CBD containing THC, how long will that argument hold up.?

@marclanders They’re weird down there.

@Rich04891613 Oh, I don't. But the pressure is building and the people want cannabis legalised. They'll get in line or out of office.

@marclanders Never underestimate RINO republicans.

@Greenthumb_one They can't resist the pressure forever. As more and more States legalise, the greater the pressure will be. Shouldn't have to be this way, but here we are.

@marclanders Kansas suffers from the same harsh reality. It is now irresponsible, #ksleg kansasreflector.com/2021/01/30/kan…

Here's my comment on a similar post. I hope that's what's going on, but we know that the DEA and Sabet and his SAM organisation, worked together to sabotage the Administrative Hearing. In addition, they've known this was coming for years and have had plenty of time to get this done. I think we will get rescheduling done, but I worry about what the ruling might say. We'll see I guess. 😎

@marclanders @AlderLaneEggs What are they waiting on? Do they want all 50 states to pass Cannabinoids legislation before they act? Congress could fix this real fast. Look how quick they passed the Hemp ban. The other option is Bondi can press the send button

I hope that's what's going on, but we know that the DEA and Sabet and his SAM organisation, worked together to sabotage the Administrative Hearing. In addition, they've known this was coming for years and have had plenty of time to get this done. I think we will get rescheduling done, but I worry about what the ruling might say. We'll see I guess. 😎

@marclanders @AlderLaneEggs The administration is busy writing an ironclad researched and reasoned rescheduling that the dolt Prohibitionist can’t undermine in court - takes a bit of time to do it properly

@PelvisRestley @AGPamBondi Let's hope not. This just can't go on. The hypocrisy is just too widely known now. 😎

@marclanders @AGPamBondi They have the opportunity to do something great here. And they will surely fumble it, lol

It’s 20 March. Today would be a FANTASTIC day to drop a final rule for rescheduling with an effective date of 30 days from now. If you catch my drift @AGPamBondi …