Emily McIntosh

@BTSMchat T2. Asking questions is tremendously difficult until you actually know the diagnosis and have a bit of a background. That is why I made this resource for newly diagnosed individuals. #BTSM #NewlyDiagnosedNovember

*Pledged*

Please VOTE for Monty! If he wins he's pledge to make a donation to brain cancer research to try to keep me (the source of treats) alive a little longer #btsm #americasfavoritepet @braincancercan

americasfavpet.com/2026/monty-98e8 Please Vote for Monty!

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@JustinLathia @JuyeunLee31 @CleveClinicFL What a record! Congratulations, @JuyeunLee31 and @JustinLathia ! Really happy to see this research moving forward!

A big congrats to @JuyeunLee31 - the 8th person from our team to start their own lab! Just like LeBron, she’s taking her talents to FL, @CleveClinicFL - cannot wait for the opening of the Lee lab at the FRIC!

Love this community. It's been amazing meeting so many of you IRL! Been an honour and a pleasure contributing.

Most days, I don’t feel particularly courageous - but I do know I’m brave, because my nephew William told me so. The day I was discharged after my first surgery, I stopped by to visit my sister’s family. After a very loud, “Ewww, Emmy, look at your HEAD!” William asked if I had been brave at the hospital. I had chosen to undergo brain surgery even after being told it might not make a difference either way, so I figured I was either brave or maybe stupid, but I responded to his question with a question: “What do you think is brave?” I’ll never forget his response because it made my heart melt a little as he talked about his younger brother. “James went to the doctor and he got a needle and didn’t even cry. He is SO brave!” That was when I realized I must be brave too, after all, I had eight needles during my hospital stay and didn’t cry once. That made me, by William’s calculation, eight times braver than a two-year-old. Since that first surgery, I’ve had another one. I’ve completed many weeks of chemotherapy, three rounds of radiation, and several intravenous infusions, still without crying. But more importantly, instead of avoiding the nuances of the horrific disease I’ve been diagnosed with and living through, I’ve chosen to use my skill set and lived experience to advocate for other patients and to contribute to research and patient-centred care. .......... Emily McIntosh, PhD in Biomechanics, BCC Engagement Ambassador, dedicated patient advocate, remarkable brain cancer survivor and thriver, and the second recipient of the Douglas MacRae Award of Courage. #12DaysOfCourage #EmilyMcIntosh @mcintose

@AshleySumrallMD @LevineCancer @NeuroOnc Hopefully not the last. Suits you well! Hope you're having a good time!

This is the first time I have presented a poster with a 🦜dress & flowers in my hair! 🌸🌺It’s a festive mtg in Hawaii! Aloha @LevineCancer #SNO25 @NeuroOnc #btsm

Unreal! He has been brilliant! Doesn't need to be qualified by his age and lack of experience. He stacks up against any other WS pitcher before him! #WANTITALL #GoJays #FinishThem

#BrainCancerAwarenessDay #ResearchIsTheOnlyWayForward #EndBrainCancer @braincancercan

WE'RE GOING TO THE WORLD SERIES!!!!! #WANTITALL

🚨The OPAL Phase 1 clinical trial for CT-179 has officially launched in Australia! 🇦🇺 This innovative oral drug is targeting glioblastoma (#GBM), a tough and aggressive brain tumor that affects thousands worldwide. 🧠💥 CT-179 works by blocking OLIG2, a key protein in GBM cancer stem cells that helps tumors grow, spread, and resist treatments. 🧬 By disrupting how OLIG2 pairs up (homodimerization), it changes the cells' behavior—pushing them to mature, die off, or stop multiplying. Preclinical tests show it crosses the blood-brain barrier and boosts effects when combined with radiation or chemo! ⚗️🔬 Developed by Curtana Pharmaceuticals starting around 2016, CT-179 has come a long way: from lab discoveries and animal studies showing tumor shrinkage, to @US_FDA orphan drug status for GBM in 2017, more funding in 2020, and now entering human trials in 2025. 📈 It's a first-in-class therapy aimed at those sneaky stem cells that cause the cancer to come back. 🌟 Remember, this is Phase 1—focused on safety, finding the right dose, and how the body handles it. ⚠️ It's early days, so no guarantees on effectiveness yet. Side effects could occur, and it's for select patients only. If you're interested, talk to your doctor or check ABCARA/COGNO for details. Let's root for breakthroughs! 💪 #Glioblastoma #BrainCancerResearch #CT179 #OPALTrial @WeTrialshub @oncodaily

On this day today, September 1, 1980 Terry Fox ran his last mile of the Marathon Of Hope ❤️🇨🇦

Name one

2 @oasis tickets aug 24 #Toronto @blogTO @braincancercan @Rogers_Stadium @OasisLive_25 #OasisLive25 #Oasis @Toronto @cityoftoronto #tickets

#Toronto @oasis tickets for #braincancer research! Please share - Let's get them sold! @NoelGallagher @liamgallagher #BTSM #GBM #LIVE25 #LiveForever

2 @oasis tickets for the Aug 24 @cityoftoronto @Rogers_Stadium show are being sold to raise money for Brain Cancer Research @braincancercan. Please share widely #Live25 #Toronto @the_edge @metromorning @culture_to @indie88toronto shorturl.at/b3gQ7

@fgaiti Arrrrggghhhh. Cheeky buggers #BTSM

We found that: 🧬 Infiltrating GBM cells adopt an uncommitted oligodendrocyte progenitor-like state ⚡ They engage in synaptic signaling and neuron-tumor crosstalk 🧠 This state is epigenetically regulated and sustained by developmental transcription factors such as ZEB1

Excited to share our first lab paper, now published in @Dev_Cell! 🧠 How do glioblastoma (GBM) cells invade the brain, and what enables them to spread so effectively?